axin1 | ENSDARG00000102964 | NCBI 57931

Details for: axin1

Gene ID: 57931

Symbol: axin1

Ensembl ID: ENSDARG00000102964

Description: axin 1

Associated with

Degradation of axin
(R-DRE-4641257)
Disassembly of the destruction complex and recruitment of axin to the membrane
(R-DRE-4641262)
Signaling by wnt
(R-DRE-195721)
Signal transduction
(R-DRE-162582)
Tcf dependent signaling in response to wnt
(R-DRE-201681)
Beta-catenin binding
(GO:0008013)
Beta-catenin destruction complex
(GO:0030877)
Cell development
(GO:0048468)
Cytoplasm
(GO:0005737)
Determination of left/right symmetry
(GO:0007368)
Dorsal/ventral axis specification
(GO:0009950)
Dorsal/ventral pattern formation
(GO:0009953)
Embryonic eye morphogenesis
(GO:0048048)
Eye development
(GO:0001654)
Fin regeneration
(GO:0031101)
Forebrain anterior/posterior pattern specification
(GO:0021797)
Forebrain development
(GO:0030900)
Forebrain neuron fate commitment
(GO:0021877)
I-smad binding
(GO:0070411)
Identical protein binding
(GO:0042802)
Lens placode formation
(GO:0001743)
Membrane
(GO:0016020)
Molecular adaptor activity
(GO:0060090)
Molecular_function
(GO:0003674)
Muscle cell development
(GO:0055001)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of wnt signaling pathway
(GO:0030178)
Negative regulation of wnt signaling pathway involved in dorsal/ventral axis specification
(GO:2000054)
Neural plate anterior/posterior regionalization
(GO:0021999)
Neural plate pattern specification
(GO:0060896)
Nucleus
(GO:0005634)
Olfactory placode formation
(GO:0030910)
Plasma membrane
(GO:0005886)
Positive regulation of jnk cascade
(GO:0046330)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)
Positive regulation of protein kinase activity
(GO:0045860)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein kinase binding
(GO:0019901)
Regulation of jnk cascade
(GO:0046328)
Somitogenesis
(GO:0001756)
Ubiquitin protein ligase binding
(GO:0031625)
Wnt signaling pathway
(GO:0016055)
Wnt signaling pathway involved in somitogenesis
(GO:0090244)

Other Information

Proteins

Axin-1
A0A8M3AY92_DANRE

Genular Protein ID: 2294630166

Symbol: AXIN1_DANRE

Name: Axin-1

UniProtKB Accession Codes:

P57094 Q499B7

Database IDs:

Citations:

PubMed ID: 10704853

Title: Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish.

PubMed ID: 10704853

DOI: 10.1016/s0925-4773(99)00319-6

PubMed ID: 12526749

Title: Ccd1, a novel protein with a DIX domain, is a positive regulator in the Wnt signaling during zebrafish neural patterning.

PubMed ID: 12526749

DOI: 10.1016/s0960-9822(02)01398-2

PubMed ID: 17681137

Title: A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida.

PubMed ID: 17681137

DOI: 10.1016/j.devcel.2007.07.006

PubMed ID: 30467143

Title: Maternal Huluwa dictates the embryonic body axis through beta-catenin in vertebrates.

PubMed ID: 30467143

DOI: 10.1126/science.aat1045

Sequence Information:

Length: 835
Mass: 94329
Checksum: 7ABEE52E1DE2FAB6
Sequence:

MSMSVNEKGI CYLPDLGSSF TEDAPRPPVP GEEGDLVSSD GRQYNHSFYS SKSDSLKNEA 
SIATPRRPDL DLGYEPEGSA SPTPPYLKWA ESLHSLLDDQ DGIHLFRTFL KQEECADMLD 
FWFACSGFRK QEANDGNEKM LKLAKAIYKK YILDNNGIVS RQIKPATKSF IKDCVTKLHI 
DPAMFDQAQT EIQTMMEENT YPLFLKSDIY LEYTRTGGES PKLFSDQSSV SGNGKVLPGY 
LPTVIEDVEW RCDQEEEQIA ESDPTPSNRL TQKLPLETVP QRVANSKRYQ DNREYRHASW 
REPVNPYYVN SGYALAPATS ANDSEQQSMS SDADTLSLTD SSVDGVPPYR YRKPHRREIH 
ESAKVNGRVP LPHIPRTNRI PKDIHVEPEK FAAELISRLE GVLREREAQE KLEERLKRVR 
LEEEGDDADI STGPSLANHR VPPAVHVQHY GGRYSEMSYN GLQLRDAHEE NPESILDEHV 
QRVMKTPGCQ SPGTGRHSPK SRSPDGLPAG KIPGLMMPLS GGQGKHQARQ GPKGEAAHLH 
HHKHIHHTHY AAAGKPKEQA EAEAARMHGG FAWNTEQHHY GPKSRNYADG MSVGPNTMDP 
MGYSSKGSTL SKRPVRKGED GRNFEMREPL PADDMERNQK ILQWMMEGEK EAGRYKRGPY 
GSISGPKKAQ GHEPARPSSV ERLGAVHPWV TAQLRNNVQP SHPFIQDPTM PPNPAPNPLT 
QLEEARRRLE EERRKSGTLQ AKQRHKNMKK QPCENITVAY YFRGEPIPYR TSVKGRIVTL 
GQFKELLTKK GSYKYYFKKV SYEFDCGVVF EEVREDDAIL PIFEEKIIGK VEKVD

Genular Protein ID: 1694308175

Symbol: A0A8M3AY92_DANRE

Name: N/A

UniProtKB Accession Codes:

A0A8M3AY92

Database IDs:

Citations:

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

Sequence Information:

Length: 871
Mass: 98236
Checksum: 249F91EA3B6B48E2
Sequence:

MSMSVNEKGI CYLPDLGSSF TEDAPRPPVP GEEGDLVSSD GRQYNHSFYS SKSDSLKNEA 
SIATPRRPDL DLGYEPEGSA SPTPPYLKWA ESLHSLLDDQ DGIHLFRTFL KQEECADMLD 
FWFACSGFRK QEANDGNEKM LKLAKAIYKK YILDNNGIVS RQIKPATKSF IKDCVMKLHI 
DPAMFDQAQT EIQTMMEENT YPLFLKSDIY LEYTRTGGES PKLFSDQSSV SGNGKVLPGY 
LPTVIEDVEW RCDQEEEQIA ESDPTPSNRL TQKLLLETVP QRVANSKRYQ DNREYRHASW 
REPVNPYYVN SGYALAPATS ANDSEQQSMS SDADTLSLTD SSVDGVPPYR YRKPHRREIH 
ESAKVNGRVP LPHIPRTNRI PKDIHVEPEK FAAELISRLE GVLREREAQE KLEERLKRVR 
LEEEGDDADI STGPSLANHR IPPAVHVQHY GGRYSEMSYN GLQLRDAHEE NPESILDEHV 
QRVMKTPGCQ SPGTGRHSPK SRSPDGLPAG KIPGLMMPLS GGQGKHQARQ GPKGEAAHLH 
HHKHIHHTHY AAAGKPKEQA EAEAARMHGG FAWNTEQHHY GPKSRNYADG MSVGPNTMDP 
MGYSSKGSTL SKRPVRKGED GRNFEMREPL PADDMERNQK ILQWMMEGEK EAGRYKRSPY 
GSISGPKKAQ GHEPARPSSV ERLGAVHPWV TAQLRNNVQP SHPFIQDPTM PPNPAPNPLT 
QLEEARRRLE EERRKSGTLQ AKQRYVMEVI QRGRTAVRPA LFPALSVVPA VSDTELSDAE 
HKNMKKQPCE NITVAYYFCG EPIPYRTSVK GRIVTLGQFK ELLTKKGSYK YYFKKVSYEF 
DCGVVFEEVR EDDAILPIFE EKIIGKVEKV D

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: axin1

Associated with

Other Information

Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish. PubMed ID: 10704853

Ccd1, a novel protein with a DIX domain, is a positive regulator in the Wnt signaling during zebrafish neural patterning. PubMed ID: 12526749

A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida. PubMed ID: 17681137