Details for: BARD1

Gene ID: 580

Symbol: BARD1

Ensembl ID: ENSG00000138376

Description: BRCA1 associated RING domain 1

Associated with

Other Information

Genular Protein ID: 775548544

Symbol: BARD1_HUMAN

Name: BRCA1-associated RING domain protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8944023

Title: Identification of a RING protein that can interact in vivo with the BRCA1 gene product.

PubMed ID: 8944023

DOI: 10.1038/ng1296-430

PubMed ID: 9425226

Title: Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers.

PubMed ID: 9425226

DOI: 10.1093/hmg/7.2.195

PubMed ID: 18089818

Title: Oncogenic BARD1 isoforms expressed in gynecological cancers.

PubMed ID: 18089818

DOI: 10.1158/0008-5472.can-07-2370

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10026184

Title: Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1.

PubMed ID: 10026184

DOI: 10.1074/jbc.274.9.5659

PubMed ID: 10477523

Title: Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50.

PubMed ID: 10477523

DOI: 10.1126/science.285.5433.1576

PubMed ID: 12890688

Title: The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.

PubMed ID: 12890688

DOI: 10.1074/jbc.c300249200

PubMed ID: 14976165

Title: BRCA1:BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.

PubMed ID: 14976165

DOI: 10.1093/hmg/ddh095

PubMed ID: 17643122

Title: CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response.

PubMed ID: 17643122

DOI: 10.1038/nsmb1277

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19261749

Title: NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

PubMed ID: 19261749

DOI: 10.1101/gad.1770309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20351172

Title: The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.

PubMed ID: 20351172

DOI: 10.1128/mcb.01056-09

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 11573085

Title: Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.

PubMed ID: 11573085

DOI: 10.1038/nsb1001-833

PubMed ID: 17550235

Title: Crystal structure of the BARD1 BRCT domains.

PubMed ID: 17550235

DOI: 10.1021/bi700323t

PubMed ID: 18842000

Title: The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50.

PubMed ID: 18842000

DOI: 10.1021/bi801115g

PubMed ID: 18480049

Title: Crystal structure of the BARD1 ankyrin repeat domain and its functional consequences.

PubMed ID: 18480049

DOI: 10.1074/jbc.m802333200

Sequence Information:

  • Length: 777
  • Mass: 86648
  • Checksum: 95E2D904046B5646
  • Sequence:
  • MPDNRQPRNR QPRIRSGNEP RSAPAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 
    VCLGGCEHIF CSNCVSDCIG TGCPVCYTPA WIQDLKINRQ LDSMIQLCSK LRNLLHDNEL 
    SDLKEDKPRK SLFNDAGNKK NSIKMWFSPR SKKVRYVVSK ASVQTQPAIK KDASAQQDSY 
    EFVSPSPPAD VSERAKKASA RSGKKQKKKT LAEINQKWNL EAEKEDGEFD SKEESKQKLV 
    SFCSQPSVIS SPQINGEIDL LASGSLTESE CFGSLTEVSL PLAEQIESPD TKSRNEVVTP 
    EKVCKNYLTS KKSLPLENNG KRGHHNRLSS PISKRCRTSI LSTSGDFVKQ TVPSENIPLP 
    ECSSPPSCKR KVGGTSGRKN SNMSDEFISL SPGTPPSTLS SSSYRRVMSS PSAMKLLPNM 
    AVKRNHRGET LLHIASIKGD IPSVEYLLQN GSDPNVKDHA GWTPLHEACN HGHLKVVELL 
    LQHKALVNTT GYQNDSPLHD AAKNGHVDIV KLLLSYGASR NAVNIFGLRP VDYTDDESMK 
    SLLLLPEKNE SSSASHCSVM NTGQRRDGPL VLIGSGLSSE QQKMLSELAV ILKAKKYTEF 
    DSTVTHVVVP GDAVQSTLKC MLGILNGCWI LKFEWVKACL RRKVCEQEEK YEIPEGPRRS 
    RLNREQLLPK LFDGCYFYLW GTFKHHPKDN LIKLVTAGGG QILSRKPKPD SDVTQTINTV 
    AYHARPDSDQ RFCTQYIIYE DLCNYHPERV RQGKVWKAPS SWFIDCVMSF ELLPLDS

Genular Protein ID: 1035215371

Symbol: A0AVN2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 777
  • Mass: 86601
  • Checksum: 108C857D8D4818CE
  • Sequence:
  • MPDNRQPRNR QPRIRSGNEP RSASAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 
    VCLGGCEHIF CSNCVSDCIG TGCPVCYTPA WIQDLKINRQ LDSMIQLCSK LRNLLHDNEL 
    SDLKEDKPRK SLFNDAGNKK NSIKMWFSPR SKKVRYVVSK ASVQTQPAIK KDASAQQDSY 
    EFVSPSPPAD VSERAKKASA RSGKKQKKKT LAEINQKWNL EAEKEDGEFD SKEESKQKLV 
    SFCSQPSVIS SPQINGEIDL LASGSLTESE CFGSLTEVSL PLAEQIESPD TKSRNEVVTP 
    EKVCKNYLTS KKSLPLENNG KRGHHNRLSS PISKRCRTSI LSTSGDFVKQ TVPSENIPLP 
    ECSSPPSCKR KVGGTSGSKN SNMSDEFISL SPGTPPSTLS SSSYRRVMSS PSAMKLLPNM 
    AVKRNHRGET LLHIASIKGD IPSVEYLLQN GSDPNVKDHA GWTPLHEACN HGHLKVVELL 
    LQHKALVNTT GYQNDSPLHD AAKNGHMDIV KLLLSYGASR NAVNIFGLRP VDYTDDESMK 
    SLLLLPEKNE SSSASHCSVM NTGQRRDGPL VLIGSGLSSE QQKMLSELAV ILKAKKYTEF 
    DSTVTHVVVP GDAVQSTLKC MLGILNGCWI LKFEWVKACL RRKVCEQEEK YEIPEGPRRS 
    RLNREQLLPK LFDGCYFYLW GTFKHHPKDN LIKLVTAGGG QILSRKPKPD SDVTQTINTV 
    AYHARPDSDQ RFCTQYIIYE DLCNYHPERV RQGKVWKAPS SWFIDCVMSF ELLPLDS

Genular Protein ID: 3077981172

Symbol: F6MDI2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 18089818

Title: Oncogenic BARD1 isoforms expressed in gynecological cancers.

PubMed ID: 18089818

DOI: 10.1158/0008-5472.CAN-07-2370

PubMed ID: 17556008

Title: Identification of BARD1 splice-isoforms involved in human trophoblast invasion.

PubMed ID: 17556008

DOI: 10.1016/j.biocel.2007.04.018

Sequence Information:

  • Length: 255
  • Mass: 29332
  • Checksum: 90C3189F2F9A520F
  • Sequence:
  • MPDNRQPRNR QPRIRSGNEP RSASAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 
    VCLGGCEHIF CSNCVSDCIG TGCPVCYTPA WIQDLKINRQ LDSMIQLCSK LRNLLHDNEL 
    SGVKACLRRK VCEQEEKYEI PEGPRRSRLN REQLLPKLFD GCYFYLWGTF KHHPKDNLIK 
    LVTAGGGQIL SRKPKPDSDV TQTINTVAYH ARPDSDQRFC TQYIIYEDLC NYHPERVRQG 
    KVWKAPSSWF ILSLN

Genular Protein ID: 592413994

Symbol: F6MDI1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 18089818

Title: Oncogenic BARD1 isoforms expressed in gynecological cancers.

PubMed ID: 18089818

DOI: 10.1158/0008-5472.CAN-07-2370

PubMed ID: 17556008

Title: Identification of BARD1 splice-isoforms involved in human trophoblast invasion.

PubMed ID: 17556008

DOI: 10.1016/j.biocel.2007.04.018

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 307
  • Mass: 35058
  • Checksum: 2FC7AF807CD518E3
  • Sequence:
  • MPDNRQPRNR QPRIRSGNEP RSAPAMEPDG RGAWAHSRAA LDRLEKLLRC SRCNIFGLRP 
    VDYTDDESMK SLLLLPEKNE SSSASHCSVM NTGQRRDGPL VLIGSGLSSE QQKMLSELAV 
    ILKAKKYTEF DSTVTHVVVP GDAVQSTLKC MLGILNGCWI LKFEWVKACL RRKVCEQEEK 
    YEIPEGPRRS RLNREQLLPK LFDGCYFYLW GTFKHHPKDN LIKLVTAGGG QILSRKPKPD 
    SDVTQTINTV AYHARPDSDQ RFCTQYIIYE DLCNYHPERV RQGKVWKAPS SWFIDCVMSF 
    ELLPLDS

Genular Protein ID: 4043846987

Symbol: F6MDI0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 18089818

Title: Oncogenic BARD1 isoforms expressed in gynecological cancers.

PubMed ID: 18089818

DOI: 10.1158/0008-5472.CAN-07-2370

PubMed ID: 17556008

Title: Identification of BARD1 splice-isoforms involved in human trophoblast invasion.

PubMed ID: 17556008

DOI: 10.1016/j.biocel.2007.04.018

Sequence Information:

  • Length: 326
  • Mass: 37122
  • Checksum: 725F94B43488BDCC
  • Sequence:
  • MPDNRQPRNR QPRIRSGNEP RSASAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 
    VCLGGCEHIF CSNIFGLRPV DYTDDESMKS LLLLPEKNES SSASHCSVMN TGQRRDGPLV 
    LIGSGLSSEQ QKMLSELAVI LKAKKYTEFD STVTHVVVPG DAVQSTLKCM LGILNGCWIL 
    KFEWVKACLR RKVCEQEEKY EIPEGPRRSR LNREQLLPKL FDGCYFYLWG TFKHHPKDNL 
    IKLVTAGGGQ ILSRKPKPDS DVTQTINTVA YHARPDSDQR FCTQYIIYED LCNYHPERVR 
    QGKVWKAPSS WFIDCVMSFE LLPLDS

Genular Protein ID: 2632898752

Symbol: A0A087WZ19_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 264
  • Mass: 30365
  • Checksum: DBCFE6853FCDC056
  • Sequence:
  • MPDNRQPRNR QPRIRSGNEP RSAPAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 
    VCLGGCEHIF CSNCVSDCIG TGCPVCYTPA WIQDLKINRQ LDSMIQLCSK LRNLLHDNEL 
    SGVKACLRRK VCEQEEKYEI PEGPRRSRLN REQLLPKLFD GCYFYLWGTF KHHPKDNLIK 
    LVTAGGGQIL SRKPKPDSDV TQTINTVAYH ARPDSDQRFC TQYIIYEDLC NYHPERVRQG 
    KVWKAPSSWF IDCVMSFELL PLDS

Genular Protein ID: 1227380321

Symbol: C9IYG1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 326
  • Mass: 37132
  • Checksum: CFE9D72C593F2E3C
  • Sequence:
  • MPDNRQPRNR QPRIRSGNEP RSAPAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 
    VCLGGCEHIF CSNIFGLRPV DYTDDESMKS LLLLPEKNES SSASHCSVMN TGQRRDGPLV 
    LIGSGLSSEQ QKMLSELAVI LKAKKYTEFD STVTHVVVPG DAVQSTLKCM LGILNGCWIL 
    KFEWVKACLR RKVCEQEEKY EIPEGPRRSR LNREQLLPKL FDGCYFYLWG TFKHHPKDNL 
    IKLVTAGGGQ ILSRKPKPDS DVTQTINTVA YHARPDSDQR FCTQYIIYED LCNYHPERVR 
    QGKVWKAPSS WFIDCVMSFE LLPLDS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.