Details for: zic2a

Gene ID: 58077

Symbol: zic2a

Ensembl ID: ENSDARG00000015554

Description: zic family member 2 (odd-paired homolog, Drosophila), a

Associated with

  • Cell proliferation in forebrain
    (GO:0021846)
  • Cell proliferation in midbrain
    (GO:0033278)
  • Central nervous system development
    (GO:0007417)
  • Diencephalon development
    (GO:0021536)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dorsal/ventral pattern formation
    (GO:0009953)
  • Embryonic retina morphogenesis in camera-type eye
    (GO:0060059)
  • Embryonic viscerocranium morphogenesis
    (GO:0048703)
  • Hindbrain development
    (GO:0030902)
  • Metal ion binding
    (GO:0046872)
  • Midbrain development
    (GO:0030901)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Neural crest cell development
    (GO:0014032)
  • Neural tube formation
    (GO:0001841)
  • Nucleus
    (GO:0005634)
  • Regulation of cell population proliferation
    (GO:0042127)
  • Regulation of retinoic acid receptor signaling pathway
    (GO:0048385)
  • Regulation of smoothened signaling pathway
    (GO:0008589)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Other Information

Genular Protein ID: 2547864719

Symbol: Q9IAT0_DANRE

Name: N/A

UniProtKB Accession Codes:

Q9IAT0 Q6P0G0

Database IDs:

ARBA 1 Bgee 1 CTD 1 EMBL 5 Ensembl 2 GO 19 Gene3D 1 HOGENOM 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 2 Proteomes 2 RefSeq 2 SAM 1 SMART 1 STRING 1 SUPFAM 1 TreeFam 1 ZFIN 2 eggNOG 1

Citations:

PubMed ID: 15151985

Title: Fgf signalling controls the dorsoventral patterning of the zebrafish embryo.

PubMed ID: 15151985

DOI: 10.1242/dev.01156

PubMed ID: 15053986

Title: Sequence relationships and expression patterns of zebrafish zic2 and zic5 genes.

PubMed ID: 15053986

DOI: 10.1016/j.modgep.2003.09.011

PubMed ID: 18248235

Title: Ventralized zebrafish embryo rescue by overexpression of Zic2a.

PubMed ID: 18248235

DOI: 10.1089/zeb.2004.1.239

PubMed ID: 16261616

Title: Zebrafish bashful/laminin-alpha 1 mutants exhibit multiple axon guidance defects.

PubMed ID: 16261616

PubMed ID: 16436624

Title: belladonna/(Ihx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain.

PubMed ID: 16436624

DOI: 10.1242/dev.02244

PubMed ID: 17215296

Title: The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum.

PubMed ID: 17215296

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 28402863

Title: Biotagging of Specific Cell Populations in Zebrafish Reveals Gene Regulatory Logic Encoded in the Nuclear Transcriptome.

PubMed ID: 28402863

PubMed ID: 28689736

Title: Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis.

PubMed ID: 28689736

PubMed ID: 28096348

Title: Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish.

PubMed ID: 28096348

PubMed ID: 29243319

Title: Zebrafish Rfx4 controls dorsal and ventral midline formation in the neural tube.

PubMed ID: 29243319

PubMed ID: 30695021

Title: Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits.

PubMed ID: 30695021

Sequence Information:

  • Length: 445
  • Mass: 49073
  • Checksum: FF70DD3150DAE4EE
  • Sequence:
    • MLLDAGHQFP GLGVGTFARH HHSSSEMQDR DLSLAQNSFV DSAHMGAFKL NHDLSPGQSS 
AFTSQAPGYP AAALGAHAAH VTSYASSPFN STRDFLFRSR GFGESSPAGG QHALFGPTAG 
SLHHSHTDSQ GHILFPGIHE QHGSHGSPNV LNGQMRLGLP GEVFGRSDQY HQVSSPRTDP 
YSAAQLHNQY GSMNMNMGMN MAAHHHHPGA FFRYMRQQCI KQELICKWID PEQLSNPKKS 
CNKTFSTMHE LVTHVSVEHV GGPEQSNHIC FWEECPRESK PFKAKYKLVN HIRVHTGEKP 
FPCPFPGCGK VFARSENLKI HKRTHTGEKP FQCEFEGCDR RFANSSDRKK HMHVHTSDKP 
YLCKMCDKSY THPSSLRKHM KVHESSPPAS DSSPAASSGY ESSTPPGLVS PSTETQSNNN 
LSPSSAVHSS NNHSSLSSNF SEWYV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.