axin2 | ENSDARG00000100149 | NCBI 58080

Details for: axin2

Gene ID: 58080

Symbol: axin2

Ensembl ID: ENSDARG00000100149

Description: axin 2 (conductin, axil)

Associated with

Degradation of axin
(R-DRE-4641257)
Signaling by wnt
(R-DRE-195721)
Signal transduction
(R-DRE-162582)
Tcf dependent signaling in response to wnt
(R-DRE-201681)
Beta-catenin binding
(GO:0008013)
Beta-catenin destruction complex
(GO:0030877)
Cell development
(GO:0048468)
Cytoplasm
(GO:0005737)
Dorsal/ventral axis specification
(GO:0009950)
Dorsal/ventral pattern formation
(GO:0009953)
Heart development
(GO:0007507)
I-smad binding
(GO:0070411)
Molecular adaptor activity
(GO:0060090)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of wnt signaling pathway involved in dorsal/ventral axis specification
(GO:2000054)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)
Positive regulation of protein kinase activity
(GO:0045860)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Regulation of centromeric sister chromatid cohesion
(GO:0070602)
Ubiquitin protein ligase binding
(GO:0031625)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Axin-2

Genular Protein ID: 2082225211

Symbol: AXIN2_DANRE

Name: Axin-2

UniProtKB Accession Codes:

P57095 Q335M5

Database IDs:

Citations:

PubMed ID: 10704853

Title: Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish.

PubMed ID: 10704853

DOI: 10.1016/s0925-4773(99)00319-6

PubMed ID: 30467143

Title: Maternal Huluwa dictates the embryonic body axis through beta-catenin in vertebrates.

PubMed ID: 30467143

DOI: 10.1126/science.aat1045

Sequence Information:

Length: 812
Mass: 91497
Checksum: 46E5ADA6DE2240CC
Sequence:

MNRTLTDPMV SSFREDDPRP PVPGEEGETT CHHPSKLAMM RPKDPVKTIM ADLRCSTARR 
DEDGLGEPEG SASPDSPLAR WTKSLHFLLG DQDGAQLFRA YLEREKCVDT LDFWFACNGF 
RQMDLKDTKT HRVAKAIYKR YIENNSIVAK QLKPATKTFI RDNIKRQQID SAMFDQAQME 
IQTAMEENAY QMFLTSDIYL EYVRTGCENP SHVNPNGLGG LKLVCGYLPT LNEEEEWSCN 
DFKAKALATV VGLSAKTLRS PPLRAVEALE KGYRSYRRSD PGNPNRFTSG YSFAPATSAN 
DSEVSSDALT DDSMSMTDSS VDAIPPYKLG SKKQLQREMQ RNMRMNGQVS LPPFPRTRRP 
PKEMTPVEPA AFAAQLIARL ERLKREQETM SSLEERLQQI QEEEERDESE MSSSSASHSL 
PLLPPGTCEE DPQAILDEHL SRVLKTPGCQ SPGLLRHSPR SRSPEQRPLP RGGLSTRSQS 
SSMNGYVPAK TFISRQSTKH IHHHYIHHHA GPKSKEQIEV EATQRVQCLC HGTSECCTAP 
YIRSRSLGRD QCASPAEVAL GHSSTLSKRL CKSGEEVNME GLENSLLQLP ADSTDRSQNV 
WQWILESDRQ TKHKPHSTQN VKKSHSLEPT RTHTWGGGGS SGHLRAHQPA HPFVQDPAMP 
PLPPPNTLAQ LEEARRRLEE VSKPSKQRHS TSSLQRDKSH PVPVQNGSSA FPMDERKDPK 
KMSGCHSSLG SETVVTYFFC GEEIPYRRMM KTHSLTLGHF KEQLRKKGNY RYFFKRASDE 
FECGAVFEEV WDDCTVLPMY EGKILGKVDR MD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.