baxa | ENSDARG00000020623 | NCBI 58081

Details for: baxa

Gene ID: 58081

Symbol: baxa

Ensembl ID: ENSDARG00000020623

Description: BCL2 associated X, apoptosis regulator a

Associated with

Activation, translocation and oligomerization of bax
(R-DRE-114294)
Apoptosis
(R-DRE-109581)
Apoptotic factor-mediated response
(R-DRE-111471)
Gene expression (transcription)
(R-DRE-74160)
Generic transcription pathway
(R-DRE-212436)
Intrinsic pathway for apoptosis
(R-DRE-109606)
Programmed cell death
(R-DRE-5357801)
Pyroptosis
(R-DRE-5620971)
Regulated necrosis
(R-DRE-5218859)
Release of apoptotic factors from the mitochondria
(R-DRE-111457)
Rna polymerase ii transcription
(R-DRE-73857)
Tp53 regulates transcription of cell cycle genes
(R-DRE-6791312)
Tp53 regulates transcription of genes involved in g2 cell cycle arrest
(R-DRE-6804114)
Transcriptional regulation by tp53
(R-DRE-3700989)
Apoptotic process
(GO:0006915)
Channel activity
(GO:0015267)
Extrinsic apoptotic signaling pathway in absence of ligand
(GO:0097192)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Membrane
(GO:0016020)
Mitochondrial fusion
(GO:0008053)
Mitochondrial outer membrane
(GO:0005741)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043280)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Regulation of apoptotic process
(GO:0042981)
Release of cytochrome c from mitochondria
(GO:0001836)
Response to cadmium ion
(GO:0046686)
Response to methylmercury
(GO:0051597)

Other Information

Proteins

Q9I9N4_DANRE

Genular Protein ID: 4287674137

Symbol: Q9I9N4_DANRE

Name: N/A

UniProtKB Accession Codes:

Q9I9N4 B2GR48 F6NYY2

Database IDs:

Citations:

PubMed ID: 10917738

Title: Genes with homology to mammalian apoptosis regulators identified in zebrafish.

PubMed ID: 10917738

DOI: 10.1038/sj.cdd.4400679

PubMed ID: 15984772

Title: Comparative effects of dietary methylmercury on gene expression in liver, skeletal muscle, and brain of the zebrafish (Danio rerio).

PubMed ID: 15984772

PubMed ID: 16322560

Title: Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish.

PubMed ID: 16322560

DOI: 10.1101/gad.1366405

PubMed ID: 15630097

Title: tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.

PubMed ID: 15630097

DOI: 10.1073/pnas.0406252102

PubMed ID: 15827121

Title: Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia.

PubMed ID: 15827121

DOI: 10.1073/pnas.0408708102

PubMed ID: 16456712

Title: Thioacetamide induced liver damage in zebrafish embryo as a disease model for steatohepatitis.

PubMed ID: 16456712

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 30618751

Title: Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder.

PubMed ID: 30618751

PubMed ID: 30684774

Title: Sex-specific alterations of lipid metabolism in zebrafish exposed to polychlorinated biphenyls.

PubMed ID: 30684774

PubMed ID: 31064769

Title: Disruption of asxl1 results in myeloproliferative neoplasms in zebrafish. .

PubMed ID: 31064769

DOI: 10.1242/dmm.035790

PubMed ID: 31323059

Title: Delay in development and behavioural abnormalities in the absence of p53 in zebrafish.

PubMed ID: 31323059

PubMed ID: 30771440

Title: Aloe emodin induces hepatotoxicity by activating NF-kappaB inflammatory pathway and P53 apoptosis pathway in zebrafish.

PubMed ID: 30771440

Sequence Information:

Length: 192
Mass: 21401
Checksum: 8A71A630A56FDC32
Sequence:

MAAPSGGGDT GSGNDQILDL GAALLNNFVY ERVRRHGDRD AEVTRSQLGG VELCDPSHKR 
LAQCLQQIGD ELDGNAQLQS MLNNSNLQPT QDVFIRVARE IFSDGKFNWG RVVALFYFAC 
RLVIKAISTR VPDIIRTIIS WTMSYIQEHV INWIREQGGW DGIRSYFGTP TWQTVGVFLA 
GVITTALVIR KM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: baxa

Associated with

Other Information

Genes with homology to mammalian apoptosis regulators identified in zebrafish. PubMed ID: 10917738

Comparative effects of dietary methylmercury on gene expression in liver, skeletal muscle, and brain of the zebrafish (Danio rerio). PubMed ID: 15984772

Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish. PubMed ID: 16322560

tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. PubMed ID: 15630097

Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia. PubMed ID: 15827121

Thioacetamide induced liver damage in zebrafish embryo as a disease model for steatohepatitis. PubMed ID: 16456712

The zebrafish reference genome sequence and its relationship to the human genome. PubMed ID: 23594743

Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder. PubMed ID: 30618751

Sex-specific alterations of lipid metabolism in zebrafish exposed to polychlorinated biphenyls. PubMed ID: 30684774

Disruption of asxl1 results in myeloproliferative neoplasms in zebrafish. . PubMed ID: 31064769

Delay in development and behavioural abnormalities in the absence of p53 in zebrafish. PubMed ID: 31323059

Aloe emodin induces hepatotoxicity by activating NF-kappaB inflammatory pathway and P53 apoptosis pathway in zebrafish. PubMed ID: 30771440