Details for: BAX
Associated with
Other Information
Genular Protein ID: 1293566266
Symbol: BAX_HUMAN
Name: Apoptosis regulator BAX
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8358790
Title: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.
PubMed ID: 8358790
PubMed ID: 7607685
Title: Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta.
PubMed ID: 7607685
PubMed ID: 9920818
Title: Identification and characterization of baxepsilon, a novel bax variant missing the BH2 and the transmembrane domains.
PubMed ID: 9920818
PubMed ID: 10772918
Title: Characterization of Bax-sigma, a cell death-inducing isoform of Bax.
PubMed ID: 10772918
PubMed ID: 11912183
Title: The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients.
PubMed ID: 11912183
DOI: 10.1093/hmg/11.6.675
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7475270
Title: Bax mutations in cell lines derived from hematological malignancies.
PubMed ID: 7475270
PubMed ID: 8521816
Title: A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions.
PubMed ID: 8521816
PubMed ID: 10228148
Title: Conformation of the Bax C-terminus regulates subcellular location and cell death.
PubMed ID: 10228148
PubMed ID: 11060313
Title: MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains.
PubMed ID: 11060313
PubMed ID: 11259440
Title: Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax.
PubMed ID: 11259440
PubMed ID: 11462023
Title: E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis.
PubMed ID: 11462023
PubMed ID: 12732850
Title: Humanin peptide suppresses apoptosis by interfering with Bax activation.
PubMed ID: 12732850
DOI: 10.1038/nature01627
PubMed ID: 15071501
Title: JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins.
PubMed ID: 15071501
PubMed ID: 15004034
Title: Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation.
PubMed ID: 15004034
PubMed ID: 15004026
Title: An anti-apoptotic viral protein that recruits Bax to mitochondria.
PubMed ID: 15004026
PubMed ID: 16113678
Title: Clusterin inhibits apoptosis by interacting with activated Bax.
PubMed ID: 16113678
DOI: 10.1038/ncb1291
PubMed ID: 16199525
PubMed ID: 16964429
Title: Sequence analysis shows that Lifeguard belongs to a new evolutionarily conserved cytoprotective family.
PubMed ID: 16964429
PubMed ID: 16509771
Title: IAN family critically regulates survival and development of T lymphocytes.
PubMed ID: 16509771
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20300062
Title: IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation.
PubMed ID: 20300062
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21458670
Title: Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol.
PubMed ID: 21458670
PubMed ID: 23235460
Title: The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist.
PubMed ID: 23235460
PubMed ID: 23055042
Title: Human Bop is a novel BH3-only member of the Bcl-2 protein family.
PubMed ID: 23055042
PubMed ID: 25609812
Title: Tom70 mediates Sendai virus-induced apoptosis on mitochondria.
PubMed ID: 25609812
DOI: 10.1128/jvi.02959-14
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27558414
Title: Enterovirus 71 2B induces cell apoptosis by directly inducing the conformational activation of the proapoptotic protein Bax.
PubMed ID: 27558414
DOI: 10.1128/jvi.01499-16
PubMed ID: 29531808
Title: PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetero-oligomerization through interaction with Bid in human colon cancer.
PubMed ID: 29531808
PubMed ID: 31690630
Title: Humanin induces conformational changes in the apoptosis regulator BAX and sequesters it into fibers, preventing mitochondrial outer-membrane permeabilization.
PubMed ID: 31690630
PubMed ID: 36361894
Title: Deubiquitinating Enzyme USP12 Regulates the Pro-Apoptosis Protein Bax.
PubMed ID: 36361894
PubMed ID: 11106734
Title: Structure of Bax: coregulation of dimer formation and intracellular localization.
PubMed ID: 11106734
PubMed ID: 16946732
Title: Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex.
PubMed ID: 16946732
PubMed ID: 18948948
Title: BAX activation is initiated at a novel interaction site.
PubMed ID: 18948948
DOI: 10.1038/nature07396
PubMed ID: 21199865
Title: Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis.
PubMed ID: 21199865
PubMed ID: 9531611
Title: Hematopoietic malignancies demonstrate loss-of-function mutations of BAX.
PubMed ID: 9531611
Sequence Information:
- Length: 192
- Mass: 21184
- Checksum: 6C0CDB0A7DEE4994
- Sequence:
MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV PQDASTKKLS ECLKRIGDEL DSNMELQRMI AAVDTDSPRE VFFRVAADMF SDGNFNWGRV VALFYFASKL VLKALCTKVP ELIRTIMGWT LDFLRERLLG WIQDQGGWDG LLSYFGTPTW QTVTIFVAGV LTASLTIWKK MG
Genular Protein ID: 4225522848
Symbol: Q5ZPJ0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 36
- Mass: 4231
- Checksum: F6F31103D577759A
- Sequence:
EQPRGGVSSR IEQGEWGGRH PSWPWTRCLR MRPPRS
Genular Protein ID: 3794058840
Symbol: Q5ZPJ1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 112
- Mass: 12608
- Checksum: 4CD21BC9AEA1258B
- Sequence:
MIAAVDTDSP REVFFRVAAD MFSDGNFNWG RVVALFYFAS KLVLKALCTK VPELIRTIMG WTLDFLRERL LGWIQDQGGW VRLLKPPHPH HRALTTAPAP PSLPPATPLG PW
Genular Protein ID: 3086669915
Symbol: I6LPK7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 140
- Mass: 15923
- Checksum: 99F1FB1E7F41A5B4
- Sequence:
MIAAVDTDSP REVFFRVAAD MFSDGNFNWG RVVALFYFAS KLVLKALCTK VPELIRTIMG WTLDFLRERL LGWIQDQGGW VRLLKPPHPH HRALTTAPAP PSLPPATPLG PWAFWSRSQW CPLPIFRSSD VVYNAFSLRV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.