Details for: NGB

Gene ID: 58157

Symbol: NGB

Ensembl ID: ENSG00000165553

Description: neuroglobin

Associated with

Other Information

Genular Protein ID: 2173345978

Symbol: NGB_HUMAN

Name: Neuroglobin

UniProtKB Accession Codes:

Q9NPG2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 4 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 4 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 neXtProt 1

Citations:

PubMed ID: 11029004

Title: A vertebrate globin expressed in the brain.

PubMed ID: 11029004

DOI: 10.1038/35035093

PubMed ID: 11820779

Title: Full-length cDNA cloning of human neuroglobin and tissue expression of rat neuroglobin.

PubMed ID: 11820779

DOI: 10.1006/bbrc.2002.6360

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11473128

Title: Biochemical characterization and ligand binding properties of neuroglobin, a novel member of the globin family.

PubMed ID: 11473128

DOI: 10.1074/jbc.m106438200

PubMed ID: 15036292

Title: Coupling of the heme and an internal disulfide bond in human neuroglobin.

PubMed ID: 15036292

DOI: 10.1016/j.micron.2003.10.019

PubMed ID: 18416560

Title: Zebrafish neuroglobin is a cell-membrane-penetrating globin.

PubMed ID: 18416560

DOI: 10.1021/bi800286m

PubMed ID: 21190290

Title: A role for human neuroglobin in apoptosis.

PubMed ID: 21190290

DOI: 10.1002/iub.405

PubMed ID: 21296891

Title: Human neuroglobin functions as a redox-regulated nitrite reductase.

PubMed ID: 21296891

DOI: 10.1074/jbc.m110.159541

PubMed ID: 21965683

Title: 14-3-3 binding and phosphorylation of neuroglobin during hypoxia modulate six-to-five heme pocket coordination and rate of nitrite reduction to nitric oxide.

PubMed ID: 21965683

DOI: 10.1074/jbc.m111.271973

PubMed ID: 12962627

Title: Human brain neuroglobin structure reveals a distinct mode of controlling oxygen affinity.

PubMed ID: 12962627

DOI: 10.1016/s0969-2126(03)00166-7

Sequence Information:

  • Length: 151
  • Mass: 16933
  • Checksum: 45A292A7D77B9CE3
  • Sequence:
    • MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE 
FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC 
LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.