Nelfb | ENSMUSG00000013465 | NCBI 58202

Details for: Nelfb

Gene ID: 58202

Symbol: Nelfb

Ensembl ID: ENSMUSG00000013465

Description: negative elongation factor complex member B

Associated with

Formation of rna pol ii elongation complex
(R-MMU-112382)
Formation of the early elongation complex
(R-MMU-113418)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Rna polymerase ii pre-transcription events
(R-MMU-674695)
Rna polymerase ii transcription
(R-MMU-73857)
Rna polymerase ii transcription elongation
(R-MMU-75955)
Tp53 regulates transcription of dna repair genes
(R-MMU-6796648)
Transcriptional regulation by tp53
(R-MMU-3700989)
Cell population proliferation
(GO:0008283)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Mitochondrial outer membrane
(GO:0005741)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of stem cell differentiation
(GO:2000737)
Negative regulation of transcription elongation by rna polymerase ii
(GO:0034244)
Nelf complex
(GO:0032021)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Rna binding
(GO:0003723)
Stem cell differentiation
(GO:0048863)

Other Information

Proteins

Negative elongation factor B

Genular Protein ID: 1773581157

Symbol: NELFB_MOUSE

Name: Negative elongation factor B

UniProtKB Accession Codes:

Q8C4Y3 A0A0X1KG62 Q69ZP4 Q99J41 Q9JJA5

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15368895

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 15368895

DOI: 10.1093/dnares/11.3.205

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 19340312

Title: Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis.

PubMed ID: 19340312

DOI: 10.1371/journal.pone.0005034

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24656816

Title: Negative elongation factor controls energy homeostasis in cardiomyocytes.

PubMed ID: 24656816

DOI: 10.1016/j.celrep.2014.02.028

PubMed ID: 25773599

Title: Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks.

PubMed ID: 25773599

DOI: 10.1016/j.molcel.2015.02.003

PubMed ID: 26010750

Title: Translational initiation at a non-AUG start codon for human and mouse negative elongation factor-B.

PubMed ID: 26010750

DOI: 10.1371/journal.pone.0127422

Sequence Information:

Length: 580
Mass: 65636
Checksum: 716FCC01C59D3F8A
Sequence:

MFAGLQDLGV ANGEDLKETL TNCTEPLKAI EQFQTENGVL LPSLQSALPF LDLHGTPRLE 
FHQSVFDELR DKLLERVSAI ASEGKAEERY KKLEDLLEKS FSLVKMPSLQ PVVMCVMKHL 
PKVPEKKLKL VMADKELYRA CAVEVKRQIW QDNQALFGDE VSPLLKQYIL EKESALFSTE 
LSVLHNFFSP SPKTRRQGEV VQKLTQMVGK NVKLYDMVLQ FLRTLFLRTR NVHYCTLRAE 
LLMSLHDLDV SDICTVDPCH KFTWCLDACI RERFVDSKRA RELQGFLDGV KKGQEQVLGD 
LSMILCDPFA INTLSLSTIR HLQELVSQET LPRDSPDLLL LLRLLALGQG AWDLIDSQVF 
KEPKMEAELI TKFLPMLMSL VVDDFTFNVD QKLPAEEKAS VTYPNTLPES FTKFLQEQRM 
ACEVGLYYVL HITKQRNKNA LLRLLPGLVE TFGDLAFSDI FLHLLTGSLV LLADEFALED 
FCSSLFDGFF LTASPRKENV HRHVLRLLLH LHARVAPSKL EALQKALEPT GQSGEAVKEL 
YSQLGEKLEQ LDHRKPSPTQ AAETPALDLP LPSVPAPATL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nelfb

Associated with

Other Information

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. PubMed ID: 15368895

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis. PubMed ID: 19340312

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Negative elongation factor controls energy homeostasis in cardiomyocytes. PubMed ID: 24656816

Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks. PubMed ID: 25773599

Translational initiation at a non-AUG start codon for human and mouse negative elongation factor-B. PubMed ID: 26010750