Pdcd1lg2 | ENSMUSG00000016498 | NCBI 58205

Details for: Pdcd1lg2

Gene ID: 58205

Symbol: Pdcd1lg2

Ensembl ID: ENSMUSG00000016498

Description: programmed cell death 1 ligand 2

Associated with

Adaptive immune system
(R-MMU-1280218)
Costimulation by the cd28 family
(R-MMU-388841)
Immune system
(R-MMU-168256)
Pd-1 signaling
(R-MMU-389948)
Adaptive immune response
(GO:0002250)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to lipopolysaccharide
(GO:0071222)
External side of plasma membrane
(GO:0009897)
Immune response
(GO:0006955)
Immune system process
(GO:0002376)
Membrane
(GO:0016020)
Negative regulation of activated t cell proliferation
(GO:0046007)
Negative regulation of interleukin-10 production
(GO:0032693)
Negative regulation of t cell proliferation
(GO:0042130)
Negative regulation of type ii interferon production
(GO:0032689)
Plasma membrane
(GO:0005886)
Positive regulation of t cell proliferation
(GO:0042102)
Protein binding
(GO:0005515)
T cell costimulation
(GO:0031295)

Other Information

Proteins

Programmed cell death 1 ligand 2

Genular Protein ID: 46981122

Symbol: PD1L2_MOUSE

Name: Programmed cell death 1 ligand 2

UniProtKB Accession Codes:

Q9WUL5

Database IDs:

Citations:

PubMed ID: 11283156

Title: B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.

PubMed ID: 11283156

DOI: 10.1084/jem.193.7.839

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 11224527

Title: PD-L2 is a second ligand for PD-1 and inhibits T cell activation.

PubMed ID: 11224527

DOI: 10.1038/85330

PubMed ID: 12719480

Title: Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction.

PubMed ID: 12719480

DOI: 10.1084/jem.20021752

PubMed ID: 18641123

Title: Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.

PubMed ID: 18641123

DOI: 10.1073/pnas.0804453105

Sequence Information:

Length: 247
Mass: 27820
Checksum: 9BFDDE14F3EC138F
Sequence:

MLLLLPILNL SLQLHPVAAL FTVTAPKEVY TVDVGSSVSL ECDFDRRECT ELEGIRASLQ 
KVENDTSLQS ERATLLEEQL PLGKALFHIP SVQVRDSGQY RCLVICGAAW DYKYLTVKVK 
ASYMRIDTRI LEVPGTGEVQ LTCQARGYPL AEVSWQNVSV PANTSHIRTP EGLYQVTSVL 
RLKPQPSRNF SCMFWNAHMK ELTSAIIDPL SRMEPKVPRT WPLHVFIPAC TIALIFLAIV 
IIQRKRI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pdcd1lg2

Associated with

Other Information

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. PubMed ID: 11283156

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

PD-L2 is a second ligand for PD-1 and inhibits T cell activation. PubMed ID: 11224527