Details for: SQOR

Gene ID: 58472

Symbol: SQOR

Ensembl ID: ENSG00000137767

Description: sulfide quinone oxidoreductase

Associated with

Other Information

Genular Protein ID: 3362790431

Symbol: SQOR_HUMAN

Name: Sulfide dehydrogenase-like

UniProtKB Accession Codes:

Q9Y6N5 Q9UQM8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 25 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 3 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 8 PRIDE 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 6 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10224084

Title: A fission yeast gene for mitochondrial sulfide oxidation.

PubMed ID: 10224084

DOI: 10.1074/jbc.274.19.13250

PubMed ID: 10810093

Title: Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.

PubMed ID: 10810093

DOI: 10.1101/gr.10.5.703

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22852582

Title: Human sulfide:quinone oxidoreductase catalyzes the first step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite.

PubMed ID: 22852582

DOI: 10.1021/bi300778t

PubMed ID: 25225291

Title: Organization of the human mitochondrial hydrogen sulfide oxidation pathway.

PubMed ID: 25225291

DOI: 10.1074/jbc.m114.602664

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29715001

Title: Modulation of catalytic promiscuity during hydrogen sulfide oxidation.

PubMed ID: 29715001

DOI: 10.1021/acschembio.8b00258

PubMed ID: 32160317

Title: Pathogenic variants in SQOR encoding sulfide:quinone oxidoreductase are a potentially treatable cause of Leigh disease.

PubMed ID: 32160317

DOI: 10.1002/jimd.12232

PubMed ID: 30905673

Title: X-ray structure of human sulfide:quinone oxidoreductase: insights into the mechanism of mitochondrial hydrogen sulfide oxidation.

PubMed ID: 30905673

DOI: 10.1016/j.str.2019.03.002

Sequence Information:

  • Length: 450
  • Mass: 49961
  • Checksum: 943ABD4049E3634D
  • Sequence:
    • MVPLVAVVSG PRAQLFACLL RLGTQQVGPL QLHTGASHAA RNHYEVLVLG GGSGGITMAA 
RMKRKVGAEN VAIVEPSERH FYQPIWTLVG AGAKQLSSSG RPTASVIPSG VEWIKARVTE 
LNPDKNCIHT DDDEKISYRY LIIALGIQLD YEKIKGLPEG FAHPKIGSNY SVKTVEKTWK 
ALQDFKEGNA IFTFPNTPVK CAGAPQKIMY LSEAYFRKTG KRSKANIIFN TSLGAIFGVK 
KYADALQEII QERNLTVNYK KNLIEVRADK QEAVFENLDK PGETQVISYE MLHVTPPMSP 
PDVLKTSPVA DAAGWVDVDK ETLQHRRYPN VFGIGDCTNL PTSKTAAAVA AQSGILDRTI 
SVIMKNQTPT KKYDGYTSCP LVTGYNRVIL AEFDYKAEPL ETFPFDQSKE RLSMYLMKAD 
LMPFLYWNMM LRGYWGGPAF LRKLFHLGMS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.