Details for: PRUNE1

Gene ID: 58497

Symbol: PRUNE1

Ensembl ID: ENSG00000143363

Description: prune exopolyphosphatase 1

Associated with

Other Information

Genular Protein ID: 220537656

Symbol: PRUN1_HUMAN

Name: Exopolyphosphatase PRUNE1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10602478

Title: Evidence for interaction between human PRUNE and nm23-H1 NDPKinase.

PubMed ID: 10602478

DOI: 10.1038/sj.onc.1203140

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10524757

Title: Sequencing analysis of forty-eight human image cDNA clones similar to Drosophila mutant protein.

PubMed ID: 10524757

DOI: 10.3109/10425179809008469

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11687967

Title: Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity.

PubMed ID: 11687967

DOI: 10.1038/sj.onc.1204874

PubMed ID: 14998490

Title: Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis.

PubMed ID: 14998490

DOI: 10.1016/s1535-6108(04)00021-2

PubMed ID: 15671547

Title: Overexpression of h-prune in breast cancer is correlated with advanced disease status.

PubMed ID: 15671547

DOI: 10.1158/1078-0432.199.11.1

PubMed ID: 16428445

Title: Glycogen synthase kinase 3 and h-prune regulate cell migration by modulating focal adhesions.

PubMed ID: 16428445

DOI: 10.1128/mcb.26.3.898-911.2006

PubMed ID: 17655525

Title: Domain mapping on the human metastasis regulator protein h-Prune reveals a C-terminal dimerization domain.

PubMed ID: 17655525

DOI: 10.1042/bj20070408

PubMed ID: 17906697

Title: Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility.

PubMed ID: 17906697

DOI: 10.1038/sj.onc.1210822

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 28211990

Title: Homozygous mutation in PRUNE1 in an Oji-Cree male with a complex neurological phenotype.

PubMed ID: 28211990

DOI: 10.1002/ajmg.a.38066

PubMed ID: 28334956

Title: PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment.

PubMed ID: 28334956

DOI: 10.1093/brain/awx014

PubMed ID: 26539891

Title: Genes that affect brain structure and function identified by rare variant analyses of mendelian neurologic disease.

PubMed ID: 26539891

DOI: 10.1016/j.neuron.2015.09.048

Sequence Information:

  • Length: 453
  • Mass: 50200
  • Checksum: 34BE1909AB89DBD5
  • Sequence:
  • MEDYLQGCRA ALQESRPLHV VLGNEACDLD STVSALALAF YLAKTTEAEE VFVPVLNIKR 
    SELPLRGDIV FFLQKVHIPE SILIFRDEID LHALYQAGQL TLILVDHHIL SKSDTALEEA 
    VAEVLDHRPI EPKHCPPCHV SVELVGSCAT LVTERILQGA PEILDRQTAA LLHGTIILDC 
    VNMDLKIGKA TPKDSKYVEK LEALFPDLPK RNDIFDSLQK AKFDVSGLTT EQMLRKDQKT 
    IYRQGVKVAI SAIYMDLEAF LQRSNLLADL HAFCQAHSYD VLVAMTIFFN THNEPVRQLA 
    IFCPHVALQT TICEVLERSH SPPLKLTPAS STHPNLHAYL QGNTQVSRKK LLPLLQEALS 
    AYFDSMKIPS GQPETADVSR EQVDKELDRA SNSLISGLSQ DEEDPPLPPT PMNSLVDECP 
    LDQGLPKLSA EAVFEKCSQI SLSQSTTASL SKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.