Details for: BCAT2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 143.0452
Cell Significance Index: -22.2500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 76.0911
Cell Significance Index: -19.3000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 58.3569
Cell Significance Index: -24.0400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 48.8856
Cell Significance Index: -23.0800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 46.3992
Cell Significance Index: -18.8500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 19.7540
Cell Significance Index: -18.8600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 18.4110
Cell Significance Index: -22.7000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 7.2270
Cell Significance Index: -19.3600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.8159
Cell Significance Index: -22.9500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 4.1792
Cell Significance Index: 38.4900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 3.4502
Cell Significance Index: 179.2300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.7422
Cell Significance Index: 314.0700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.2731
Cell Significance Index: 156.5400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.0593
Cell Significance Index: 956.4500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.8037
Cell Significance Index: 21.5400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.7791
Cell Significance Index: 10.6300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.7150
Cell Significance Index: 116.2800 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.6826
Cell Significance Index: 5.4500 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.5429
Cell Significance Index: 4.5600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.5138
Cell Significance Index: 15.0900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.4876
Cell Significance Index: 66.9600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4551
Cell Significance Index: 90.3100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4134
Cell Significance Index: 28.5900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4014
Cell Significance Index: 143.9600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.3808
Cell Significance Index: 10.3700 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.3679
Cell Significance Index: 5.1600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.3369
Cell Significance Index: 15.7100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3282
Cell Significance Index: 179.2600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.2176
Cell Significance Index: 6.9700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2049
Cell Significance Index: 5.7300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1994
Cell Significance Index: 23.5100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1877
Cell Significance Index: 8.5100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1842
Cell Significance Index: 3.9900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1778
Cell Significance Index: 33.8400 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1696
Cell Significance Index: 21.9100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1683
Cell Significance Index: 5.8500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1673
Cell Significance Index: 115.6800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1638
Cell Significance Index: 27.9700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.1593
Cell Significance Index: 4.1900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1454
Cell Significance Index: 11.1600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1428
Cell Significance Index: 3.5700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1148
Cell Significance Index: 50.7600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1053
Cell Significance Index: 66.8900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0924
Cell Significance Index: 174.0000 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.0855
Cell Significance Index: 1.7900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0821
Cell Significance Index: 3.8600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0790
Cell Significance Index: 10.1300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0646
Cell Significance Index: 1.8600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0576
Cell Significance Index: 4.2900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0528
Cell Significance Index: 71.7500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0521
Cell Significance Index: 3.3600 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.0515
Cell Significance Index: 0.5600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0509
Cell Significance Index: 1.3600 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0488
Cell Significance Index: 0.5100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0470
Cell Significance Index: 9.4300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0376
Cell Significance Index: 57.9200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0292
Cell Significance Index: 22.1100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0200
Cell Significance Index: 36.9600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0014
Cell Significance Index: -0.1400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0024
Cell Significance Index: -1.7600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0056
Cell Significance Index: -4.1100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0113
Cell Significance Index: -0.7000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0159
Cell Significance Index: -9.9500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0184
Cell Significance Index: -10.3500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0185
Cell Significance Index: -8.3900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0206
Cell Significance Index: -2.9900 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.0215
Cell Significance Index: -0.3000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0334
Cell Significance Index: -3.4100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0441
Cell Significance Index: -0.9400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0484
Cell Significance Index: -3.0500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0591
Cell Significance Index: -12.4500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0603
Cell Significance Index: -1.0100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0657
Cell Significance Index: -18.8900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.0747
Cell Significance Index: -1.1200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0779
Cell Significance Index: -9.0800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1032
Cell Significance Index: -4.5700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1099
Cell Significance Index: -7.7800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1119
Cell Significance Index: -12.8200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1158
Cell Significance Index: -6.0800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1338
Cell Significance Index: -7.5100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1394
Cell Significance Index: -5.2800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1413
Cell Significance Index: -16.1300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1490
Cell Significance Index: -10.0200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1758
Cell Significance Index: -4.4900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1817
Cell Significance Index: -18.9200 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.2025
Cell Significance Index: -2.9900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.2041
Cell Significance Index: -4.9800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2255
Cell Significance Index: -17.8600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2294
Cell Significance Index: -11.9500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3077
Cell Significance Index: -18.8700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.3180
Cell Significance Index: -5.4500 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.3372
Cell Significance Index: -5.8300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3525
Cell Significance Index: -9.0600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3791
Cell Significance Index: -11.1700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.3800
Cell Significance Index: -4.5300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3937
Cell Significance Index: -8.6200 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.4239
Cell Significance Index: -5.3500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.4443
Cell Significance Index: -5.6900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4471
Cell Significance Index: -11.9600 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.4515
Cell Significance Index: -5.6300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 386928016
Symbol: BCAT2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9165094
Title: Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm).
PubMed ID: 9165094
PubMed ID: 11170829
Title: Molecular cloning and characterization of placental tissue protein 18 (PP18a)/human mitochondrial branched-chain aminotransferase (BCATm) and its novel alternatively spliced PP18b variant.
PubMed ID: 11170829
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8702755
Title: Two yeast homologs of ECA39, a target for c-Myc regulation, code for cytosolic and mitochondrial branched-chain amino acid aminotransferases.
PubMed ID: 8702755
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25653144
Title: Hypervalinemia and hyperleucine-isoleucinemia caused by mutations in the branched-chain-amino-acid aminotransferase gene.
PubMed ID: 25653144
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 11264579
Title: The structure of human mitochondrial branched-chain aminotransferase.
PubMed ID: 11264579
PubMed ID: 12269802
Title: Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms.
PubMed ID: 12269802
DOI: 10.1021/bi020221c
PubMed ID: 16141215
Title: Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.
PubMed ID: 16141215
PubMed ID: 17050531
Title: Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis.
PubMed ID: 17050531
Sequence Information:
- Length: 392
- Mass: 44288
- Checksum: EC07047264B190DA
- Sequence:
MAAAALGQIW ARKLLSVPWL LCGPRRYASS SFKAADLQLE MTQKPHKKPG PGEPLVFGKT FTDHMLMVEW NDKGWGQPRI QPFQNLTLHP ASSSLHYSLQ LFEGMKAFKG KDQQVRLFRP WLNMDRMLRS AMRLCLPSFD KLELLECIRR LIEVDKDWVP DAAGTSLYVR PVLIGNEPSL GVSQPTRALL FVILCPVGAY FPGGSVTPVS LLADPAFIRA WVGGVGNYKL GGNYGPTVLV QQEALKRGCE QVLWLYGPDH QLTEVGTMNI FVYWTHEDGV LELVTPPLNG VILPGVVRQS LLDMAQTWGE FRVVERTITM KQLLRALEEG RVREVFGSGT ACQVCPVHRI LYKDRNLHIP TMENGPELIL RFQKELKEIQ YGIRAHEWMF PV
Genular Protein ID: 256333818
Symbol: B3KSI3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 352
- Mass: 39916
- Checksum: 2BF282313ABEC40A
- Sequence:
MTQKPHKKPG PGEPLVFGKT FTDHMLMVEW NDKGWGQPRI QPFQNLTLHP ASSSLHYSLQ LFEGMKAFKG KDQQVRLFRP WLNMDRMLRS AMRLCLPSFD KLELLECIRR LIEVDKDWVP DAAGTSLYVR PVLIGNEPSL GVSQPTRALL FVILCPVGAY FPGGSVTPVS LLADPAFIRA WVGGVGNYKL GGNYGPTVLV QQEALKRGCE QVLWLYGPDH QLTEVGTMNI FVYWTHEDGV LELVTPPLNG VILPGVVRQS LLDMAQTWGE FRVVERTITM KQLLRALEEG RVREVFGSGT ACQVCPVHRI LYKDRNLHIP TMENGPELIL RFQKELKEIQ YGIRAHEWMF PV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.