Nr1h2 | ENSRNOG00000019812 | NCBI 58851

Details for: Nr1h2

Gene ID: 58851

Symbol: Nr1h2

Ensembl ID: ENSRNOG00000019812

Description: nuclear receptor subfamily 1, group H, member 2

Associated with

Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Metabolism of proteins
(R-RNO-392499)
Nr1h2 & nr1h3 regulate gene expression to control bile acid homeostasis
(R-RNO-9623433)
Nr1h2 and nr1h3-mediated signaling
(R-RNO-9024446)
Nr1h3 & nr1h2 regulate gene expression linked to cholesterol transport and efflux
(R-RNO-9029569)
Nuclear receptor transcription pathway
(R-RNO-383280)
Plasma lipoprotein assembly, remodeling, and clearance
(R-RNO-174824)
Plasma lipoprotein clearance
(R-RNO-8964043)
Post-translational protein modification
(R-RNO-597592)
Rna polymerase ii transcription
(R-RNO-73857)
Signaling by nuclear receptors
(R-RNO-9006931)
Signal transduction
(R-RNO-162582)
Sumo e3 ligases sumoylate target proteins
(R-RNO-3108232)
Sumoylation
(R-RNO-2990846)
Sumoylation of intracellular receptors
(R-RNO-4090294)
Transport of small molecules
(R-RNO-382551)
Vldlr internalisation and degradation
(R-RNO-8866427)
Apolipoprotein a-i receptor binding
(GO:0034191)
Atpase binding
(GO:0051117)
Cell differentiation
(GO:0030154)
Cellular lipid metabolic process
(GO:0044255)
Cholesterol homeostasis
(GO:0042632)
Chromatin dna binding
(GO:0031490)
Cytoplasm
(GO:0005737)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Intracellular receptor signaling pathway
(GO:0030522)
Lipid homeostasis
(GO:0055088)
Negative regulation of cholesterol storage
(GO:0010887)
Negative regulation of cold-induced thermogenesis
(GO:0120163)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of lipid transport
(GO:0032369)
Negative regulation of pinocytosis
(GO:0048550)
Negative regulation of proteolysis
(GO:0045861)
Negative regulation of response to endoplasmic reticulum stress
(GO:1903573)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear receptor activity
(GO:0004879)
Nuclear retinoid x receptor binding
(GO:0046965)
Nucleus
(GO:0005634)
Phosphatidylcholine acyl-chain remodeling
(GO:0036151)
Positive regulation of cholesterol efflux
(GO:0010875)
Positive regulation of cholesterol transport
(GO:0032376)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of fatty acid biosynthetic process
(GO:0045723)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of high-density lipoprotein particle assembly
(GO:0090108)
Positive regulation of lipid storage
(GO:0010884)
Positive regulation of mirna transcription
(GO:1902895)
Positive regulation of pancreatic juice secretion
(GO:0090187)
Positive regulation of protein metabolic process
(GO:0051247)
Positive regulation of secretion of lysosomal enzymes
(GO:0090340)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of triglyceride biosynthetic process
(GO:0010867)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to nutrient levels
(GO:0031667)
Retinoic acid receptor signaling pathway
(GO:0048384)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Sequence-specific dna binding
(GO:0043565)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Oxysterols receptor LXR-beta

Genular Protein ID: 1747471249

Symbol: NR1H2_RAT

Name: Oxysterols receptor LXR-beta

UniProtKB Accession Codes:

Q62755 Q62694

Database IDs:

Citations:

PubMed ID: 7892230

Title: OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor.

PubMed ID: 7892230

DOI: 10.1073/pnas.92.6.2096

PubMed ID: 7971966

Title: Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors.

PubMed ID: 7971966

DOI: 10.1073/pnas.91.23.10809

Sequence Information:

Length: 446
Mass: 49736
Checksum: 13DF6DC2F0F5FA4D
Sequence:

MSSPTSSLDT PLPGNGSPQP STSSTSPTIK EEGQETDPPP GSEGSSSAYI VVILEPEDEP 
ERKRKKGPAP KMLGHELCRV CGDKASGFHY NVLSCEGCKG FFRRSVVHGG AGRYACRGSG 
TCQMDAFMRR KCQLCRLRKC KEAGMREQCV LSEEQIRKKK IQKQQQQQPP PPTEPASGSS 
ARPAASPGTS EASSQGSGEG EGIQLTAAQE LMIQQLVAAQ LQCNKRSFSD QPKVTPWPLG 
ADPQSRDARQ QRFAHFTELA IISVQEIVDF AKQVPGFLQL GREDQIALLK ASTIEIMLLE 
TARRYNHETE CITFLKDFTY SKDDFHRAGL QVEFINPIFE FSRAMRRLGL DDAEYALLIA 
INIFSADRPN VQEPSRVEAL QQPYVEALLS YTRIKRPQDQ LRFPRMLMKL VSLRTLSSVH 
SEQVFALRLQ DKKLPPLLSE IWDVHE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.