Details for: Gas6

Gene ID: 58935

Symbol: Gas6

Ensembl ID: ENSRNOG00000018233

Description: growth arrest specific 6

Associated with

  • Cell surface interactions at the vascular wall
    (R-RNO-202733)
  • Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
    (R-RNO-159854)
  • Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
    (R-RNO-163841)
  • Hemostasis
    (R-RNO-109582)
  • Metabolism of proteins
    (R-RNO-392499)
  • Platelet activation, signaling and aggregation
    (R-RNO-76002)
  • Platelet degranulation
    (R-RNO-114608)
  • Post-translational protein modification
    (R-RNO-597592)
  • Post-translational protein phosphorylation
    (R-RNO-8957275)
  • Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
    (R-RNO-381426)
  • Removal of aminoterminal propeptides from gamma-carboxylated proteins
    (R-RNO-159782)
  • Response to elevated platelet cytosolic ca2+
    (R-RNO-76005)
  • Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the golgi apparatus
    (R-RNO-159763)
  • Animal organ regeneration
    (GO:0031100)
  • Apoptotic cell clearance
    (GO:0043277)
  • Apoptotic process
    (GO:0006915)
  • B cell chemotaxis
    (GO:0035754)
  • Blood coagulation
    (GO:0007596)
  • Calcium ion binding
    (GO:0005509)
  • Calcium ion transmembrane transport
    (GO:0070588)
  • Cell-substrate adhesion
    (GO:0031589)
  • Cell surface receptor signaling pathway
    (GO:0007166)
  • Cellular response to glucose stimulus
    (GO:0071333)
  • Cellular response to growth factor stimulus
    (GO:0071363)
  • Cellular response to interferon-alpha
    (GO:0035457)
  • Cellular response to starvation
    (GO:0009267)
  • Cellular response to vitamin k
    (GO:0071307)
  • Cellular response to xenobiotic stimulus
    (GO:0071466)
  • Cysteine-type endopeptidase inhibitor activity involved in apoptotic process
    (GO:0043027)
  • Cytoplasm
    (GO:0005737)
  • Dendritic cell differentiation
    (GO:0097028)
  • Enzyme-linked receptor protein signaling pathway
    (GO:0007167)
  • Extracellular matrix assembly
    (GO:0085029)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Fibroblast apoptotic process
    (GO:0044346)
  • Fusion of virus membrane with host plasma membrane
    (GO:0019064)
  • Growth factor activity
    (GO:0008083)
  • Hematopoietic stem cell migration to bone marrow
    (GO:0097241)
  • Myeloid cell apoptotic process
    (GO:0033028)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Negative regulation of biomineral tissue development
    (GO:0070168)
  • Negative regulation of dendritic cell apoptotic process
    (GO:2000669)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of endothelial cell apoptotic process
    (GO:2000352)
  • Negative regulation of fibroblast apoptotic process
    (GO:2000270)
  • Negative regulation of interleukin-1 production
    (GO:0032692)
  • Negative regulation of interleukin-6 production
    (GO:0032715)
  • Negative regulation of myeloid cell apoptotic process
    (GO:0033033)
  • Negative regulation of oligodendrocyte apoptotic process
    (GO:1900142)
  • Negative regulation of renal albumin absorption
    (GO:2000533)
  • Negative regulation of tumor necrosis factor-mediated signaling pathway
    (GO:0010804)
  • Negative regulation of tumor necrosis factor production
    (GO:0032720)
  • Negative regulation of type ii interferon production
    (GO:0032689)
  • Neuron migration
    (GO:0001764)
  • Phagocytosis
    (GO:0006909)
  • Phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0043491)
  • Phosphatidylserine binding
    (GO:0001786)
  • Positive regulation of cytokine-mediated signaling pathway
    (GO:0001961)
  • Positive regulation of dendritic cell chemotaxis
    (GO:2000510)
  • Positive regulation of erk1 and erk2 cascade
    (GO:0070374)
  • Positive regulation of fibroblast proliferation
    (GO:0048146)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of glomerular filtration
    (GO:0003104)
  • Positive regulation of natural killer cell differentiation
    (GO:0032825)
  • Positive regulation of phagocytosis
    (GO:0050766)
  • Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051897)
  • Positive regulation of protein export from nucleus
    (GO:0046827)
  • Positive regulation of protein phosphorylation
    (GO:0001934)
  • Positive regulation of tor signaling
    (GO:0032008)
  • Protein-macromolecule adaptor activity
    (GO:0030674)
  • Protein localization to plasma membrane
    (GO:0072659)
  • Receptor-mediated virion attachment to host cell
    (GO:0046813)
  • Receptor ligand activity
    (GO:0048018)
  • Receptor tyrosine kinase binding
    (GO:0030971)
  • Signaling receptor binding
    (GO:0005102)
  • Signal transduction
    (GO:0007165)
  • Symbiont entry into host cell
    (GO:0046718)
  • Tissue regeneration
    (GO:0042246)
  • Tissue remodeling
    (GO:0048771)
  • Viral genome replication
    (GO:0019079)

Other Information

Genular Protein ID: 2000459188

Symbol: Q6IRL1_RAT

Name: N/A

UniProtKB Accession Codes:

Q6IRL1

Database IDs:

ARBA 7 AlphaFoldDB 1 CDD 2 CTD 1 EMBL 2 GO 3 Gene3D 3 Genevisible 1 InterPro 10 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 11 PROSITE-ProRule 2 Pfam 5 RGD 2 RefSeq 1 SAM 1 SMART 4 SUPFAM 4

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 674
  • Mass: 74672
  • Checksum: CC9A5EBD04480AE7
  • Sequence:
    • MPPPPGPTAA LGTALLLLLL ASESSHTVLL RAREAAQFLR PRQRRAYQVF EEAKQGHLER 
ECVEEVCSKE EAREVFENDP ETDYFYPRYQ ECMRKYGRPE DKNPNFATCV KNLPDQCTPN 
PCDKKGTQLC QDLMGNFFCL CKDGWGGRLC DKDVNECSQK NGGCSQVCHN KPGSFQCACH 
SGFSLQSDNK SCQDIDECTD SDTCGDARCK NLPGSYSCLC DKGYTYSSKE KTCQDVDECQ 
QDRCEQTCVN SPGSYTCHCN GRGGLKLSPD MDTCEDILPC VPFSMAKSVK SLYLGRMFSG 
TPVIRLRFKR LQPTRLLAEF DFRTFDPEGV LFFAGGRSDS TWIVLGFRAG RLELQLRYNG 
VGRITSSGPT INHGMWQTIS VEELDRNLVI KVNKDAVMKI AVAGGLFQLE RGLYHLNLTV 
GGIPFKESDL VQPINPRLDG CMRSWNWLNG EDSAIQETVK ANTKMQCFSV TERGSFFPGN 
GFAFYSLNYT RTSLDVGTET TWEVEVVARI RPATDTGVLM ALVGDKDVVL LSVALVDYHS 
TKKLKKQLVV LAVENVALAL MEIKVCDSQE HTVTVSLRDG EATLEVDGTK GQSEVSTAQL 
QERLDLLKTR LQGSVLTFVG GLPDVQVTST PVTAFYRGCM TLEVNGKTLD LDTASYKHSD 
ITSHSCPPVE HVTA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.