Dynll1 | ENSRNOG00000011222 | NCBI 58945

Details for: Dynll1

Gene ID: 58945

Symbol: Dynll1

Ensembl ID: ENSRNOG00000011222

Description: dynein light chain LC8-type 1

Associated with

Activation of bh3-only proteins
(R-RNO-114452)
Activation of bim and translocation to mitochondria
(R-RNO-111446)
Adaptive immune system
(R-RNO-1280218)
Aggrephagy
(R-RNO-9646399)
Amplification of signal from the kinetochores
(R-RNO-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-RNO-141444)
Anchoring of the basal body to the plasma membrane
(R-RNO-5620912)
Apoptosis
(R-RNO-109581)
Asparagine n-linked glycosylation
(R-RNO-446203)
Aurka activation by tpx2
(R-RNO-8854518)
Autophagy
(R-RNO-9612973)
Cell cycle
(R-RNO-1640170)
Cell cycle, mitotic
(R-RNO-69278)
Cell cycle checkpoints
(R-RNO-69620)
Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Centrosome maturation
(R-RNO-380287)
Cilium assembly
(R-RNO-5617833)
Copi-independent golgi-to-er retrograde traffic
(R-RNO-6811436)
Copi-mediated anterograde transport
(R-RNO-6807878)
Eml4 and nudc in mitotic spindle formation
(R-RNO-9648025)
Er to golgi anterograde transport
(R-RNO-199977)
G2/m transition
(R-RNO-69275)
Golgi-to-er retrograde transport
(R-RNO-8856688)
Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
(R-RNO-3371497)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Intra-golgi and retrograde golgi-to-er traffic
(R-RNO-6811442)
Intraflagellar transport
(R-RNO-5620924)
Intrinsic pathway for apoptosis
(R-RNO-109606)
Loss of nlp from mitotic centrosomes
(R-RNO-380259)
Loss of proteins required for interphase microtubule organization from the centrosome
(R-RNO-380284)
Macroautophagy
(R-RNO-1632852)
Membrane trafficking
(R-RNO-199991)
Metabolism of proteins
(R-RNO-392499)
Mhc class ii antigen presentation
(R-RNO-2132295)
Mitotic anaphase
(R-RNO-68882)
Mitotic g2-g2/m phases
(R-RNO-453274)
Mitotic metaphase and anaphase
(R-RNO-2555396)
Mitotic prometaphase
(R-RNO-68877)
Mitotic spindle checkpoint
(R-RNO-69618)
M phase
(R-RNO-68886)
Neutrophil degranulation
(R-RNO-6798695)
Organelle biogenesis and maintenance
(R-RNO-1852241)
Post-translational protein modification
(R-RNO-597592)
Programmed cell death
(R-RNO-5357801)
Recruitment of mitotic centrosome proteins and complexes
(R-RNO-380270)
Recruitment of numa to mitotic centrosomes
(R-RNO-380320)
Regulation of plk1 activity at g2/m transition
(R-RNO-2565942)
Resolution of sister chromatid cohesion
(R-RNO-2500257)
Rho gtpase effectors
(R-RNO-195258)
Rho gtpases activate formins
(R-RNO-5663220)
Selective autophagy
(R-RNO-9663891)
Separation of sister chromatids
(R-RNO-2467813)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signal transduction
(R-RNO-162582)
Transport to the golgi and subsequent modification
(R-RNO-948021)
Vesicle-mediated transport
(R-RNO-5653656)
Apoptotic process
(GO:0006915)
Axon cytoplasm
(GO:1904115)
Centrosome
(GO:0005813)
Cilium
(GO:0005929)
Cop9 signalosome
(GO:0008180)
Cytoplasm
(GO:0005737)
Cytoplasmic dynein complex
(GO:0005868)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Dynein complex
(GO:0030286)
Dynein intermediate chain binding
(GO:0045505)
Enzyme binding
(GO:0019899)
Enzyme inhibitor activity
(GO:0004857)
Identical protein binding
(GO:0042802)
Intraciliary retrograde transport
(GO:0035721)
Kinetochore
(GO:0000776)
Membrane
(GO:0016020)
Microtubule
(GO:0005874)
Mitochondrion
(GO:0005739)
Mitocytosis
(GO:0160040)
Mitotic spindle
(GO:0072686)
Motile cilium assembly
(GO:0044458)
Negative regulation of nitric oxide biosynthetic process
(GO:0045019)
Negative regulation of phosphorylation
(GO:0042326)
Nitric-oxide synthase inhibitor activity
(GO:0036487)
Nitric-oxide synthase regulator activity
(GO:0030235)
Nucleus
(GO:0005634)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0035774)
Positive regulation of non-motile cilium assembly
(GO:1902857)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Regulation of mitochondrial membrane potential
(GO:0051881)
Scaffold protein binding
(GO:0097110)
Secretory granule
(GO:0030141)
Spermatid development
(GO:0007286)
Substantia nigra development
(GO:0021762)

Other Information

Proteins

Dynein light chain 1, cytoplasmic

Genular Protein ID: 2496575271

Symbol: DYL1_RAT

Name: Dynein light chain 1, cytoplasmic

UniProtKB Accession Codes:

P63170 Q15701

Database IDs:

Citations:

PubMed ID: 8864115

Title: PIN: an associated protein inhibitor of neuronal nitric oxide synthase.

PubMed ID: 8864115

DOI: 10.1126/science.274.5288.774

PubMed ID: 9299562

Title: Distribution of protein inhibitor of neuronal nitric oxide synthase in rat brain.

PubMed ID: 9299562

DOI: 10.1006/bbrc.1997.7361

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8702622

Title: Brain cytoplasmic and flagellar outer arm dyneins share a highly conserved Mr 8,000 light chain.

PubMed ID: 8702622

DOI: 10.1074/jbc.271.32.19358

PubMed ID: 11746667

Title: Light chains of mammalian cytoplasmic dynein: identification and characterization of a family of LC8 light chains.

PubMed ID: 11746667

DOI: 10.1002/cm.1036

PubMed ID: 11602781

Title: Molecular basis for the interaction between rabies virus phosphoprotein P and the dynein light chain LC8: dissociation of dynein-binding properties and transcriptional functionality of P.

PubMed ID: 11602781

DOI: 10.1099/0022-1317-82-11-2691

PubMed ID: 16133941

Title: Subcellular localization of PMES-2 proteins regulated by their two cytoskeleton-associated domains.

PubMed ID: 16133941

DOI: 10.1007/s10571-005-4955-5

PubMed ID: 21478148

Title: Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection.

PubMed ID: 21478148

DOI: 10.1074/jbc.m110.197707

PubMed ID: 11178896

Title: Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain.

PubMed ID: 11178896

DOI: 10.1006/jmbi.2000.4374

Sequence Information:

Length: 89
Mass: 10366
Checksum: F5E7647D092BEB3A
Sequence:

MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY NPTWHCIVGR 
NFGSYVTHET KHFIYFYLGQ VAILLFKSG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Dynll1

Associated with

Other Information

PIN: an associated protein inhibitor of neuronal nitric oxide synthase. PubMed ID: 8864115

Distribution of protein inhibitor of neuronal nitric oxide synthase in rat brain. PubMed ID: 9299562

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Brain cytoplasmic and flagellar outer arm dyneins share a highly conserved Mr 8,000 light chain. PubMed ID: 8702622

Light chains of mammalian cytoplasmic dynein: identification and characterization of a family of LC8 light chains. PubMed ID: 11746667

Molecular basis for the interaction between rabies virus phosphoprotein P and the dynein light chain LC8: dissociation of dynein-binding properties and transcriptional functionality of P. PubMed ID: 11602781

Subcellular localization of PMES-2 proteins regulated by their two cytoskeleton-associated domains. PubMed ID: 16133941

Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. PubMed ID: 21478148

Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain. PubMed ID: 11178896