Crhr1 | ENSRNOG00000004900 | NCBI 58959

Details for: Crhr1

Gene ID: 58959

Symbol: Crhr1

Ensembl ID: ENSRNOG00000004900

Description: corticotropin releasing hormone receptor 1

Associated with

Class b/2 (secretin family receptors)
(R-RNO-373080)
Gpcr ligand binding
(R-RNO-500792)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Adrenal gland development
(GO:0030325)
Apical part of cell
(GO:0045177)
Behavioral response to cocaine
(GO:0048148)
Behavioral response to ethanol
(GO:0048149)
Behavioral response to pain
(GO:0048266)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to corticotropin-releasing hormone stimulus
(GO:0071376)
Corticotrophin-releasing factor receptor activity
(GO:0015056)
Corticotropin-releasing hormone binding
(GO:0051424)
Corticotropin-releasing hormone receptor activity
(GO:0043404)
Corticotropin secretion
(GO:0051458)
Dendrite
(GO:0030425)
Dendritic spine
(GO:0043197)
Epithelial cell differentiation
(GO:0030855)
Exploration behavior
(GO:0035640)
Fear response
(GO:0042596)
Feeding behavior
(GO:0007631)
G-protein alpha-subunit binding
(GO:0001965)
General adaptation syndrome, behavioral process
(GO:0051867)
G protein-coupled peptide receptor activity
(GO:0008528)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hormone-mediated signaling pathway
(GO:0009755)
Hypothalamus development
(GO:0021854)
Locomotory exploration behavior
(GO:0035641)
Long-term synaptic potentiation
(GO:0060291)
Membrane
(GO:0016020)
Memory
(GO:0007613)
Multivesicular body
(GO:0005771)
Negative regulation of epinephrine secretion
(GO:0032811)
Negative regulation of feeding behavior
(GO:2000252)
Negative regulation of neuron apoptotic process
(GO:0043524)
Neuronal cell body
(GO:0043025)
Neuron projection
(GO:0043005)
Neuropeptide signaling pathway
(GO:0007218)
Peptide binding
(GO:0042277)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of camp-mediated signaling
(GO:0043950)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of mast cell degranulation
(GO:0043306)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Regulation of corticosterone secretion
(GO:2000852)
Regulation of synaptic plasticity
(GO:0048167)
Response to electrical stimulus
(GO:0051602)
Response to hypoxia
(GO:0001666)
Response to immobilization stress
(GO:0035902)
Trans-golgi network
(GO:0005802)
Vesicle
(GO:0031982)
Visual learning
(GO:0008542)

Other Information

Proteins

Corticotropin-releasing factor receptor 1
B3SXS3_RAT

Genular Protein ID: 2506314001

Symbol: CRFR1_RAT

Name: Corticotropin-releasing factor receptor 1

UniProtKB Accession Codes:

P35353

Database IDs:

Citations:

PubMed ID: 8243338

Title: Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor.

PubMed ID: 8243338

DOI: 10.1210/endo.133.6.8243338

PubMed ID: 8274282

Title: Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain.

PubMed ID: 8274282

DOI: 10.1016/0896-6273(93)90230-o

PubMed ID: 8662941

Title: The genomic structure of the rat corticotropin releasing factor receptor. A member of the class II G protein-coupled receptors.

PubMed ID: 8662941

DOI: 10.1074/jbc.271.24.14519

PubMed ID: 11567096

Title: Functional and protein chemical characterization of the N-terminal domain of the rat corticotropin-releasing factor receptor 1.

PubMed ID: 11567096

DOI: 10.1110/ps.12101

PubMed ID: 23300088

Title: Post-synaptic density-95 (PSD-95) binding capacity of G-protein-coupled receptor 30 (GPR30), an estrogen receptor that can be identified in hippocampal dendritic spines.

PubMed ID: 23300088

DOI: 10.1074/jbc.m112.412478

Sequence Information:

Length: 415
Mass: 47842
Checksum: 48D6704B31D4C013
Sequence:

MGRRPQLRLV KALLLLGLNP VSTSLQDQRC ENLSLTSNVS GLQCNASVDL IGTCWPRSPA 
GQLVVRPCPA FFYGVRYNTT NNGYRECLAN GSWAARVNYS ECQEILNEEK KSKVHYHVAV 
IINYLGHCIS LVALLVAFVL FLRLRSIRCL RNIIHWNLIS AFILRNATWF VVQLTVSPEV 
HQSNVAWCRL VTAAYNYFHV TNFFWMFGEG CYLHTAIVLT YSTDRLRKWM FVCIGWGVPF 
PIIVAWAIGK LHYDNEKCWF GKRPGVYTDY IYQGPMILVL LINFIFLFNI VRILMTKLRA 
STTSETIQYR KAVKATLVLL PLLGITYMLF FVNPGEDEVS RVVFIYFNSF LESFQGFFVS 
VFYCFLNSEV RSAIRKRWRR WQDKHSIRAR VARAMSIPTS PTRVSFHSIK QSTAV

Genular Protein ID: 163237603

Symbol: B3SXS3_RAT

Name: N/A

UniProtKB Accession Codes:

B3SXS3

Database IDs:

Sequence Information:

Length: 414
Mass: 47714
Checksum: F7268127E81C159B
Sequence:

MGRRPQLRLV KALLLLGLNP VSTSLQDQRC ENLSLTSNVS GLQCNASVDL IGTCWPRSPA 
GQLVVRPCPA FFYGVRYNTT NNGYRECLAN GSWAARVNYS ECQEILNEEK SKVHYHVAVI 
INYLGHCISL VALLVAFVLF LRLRSIRCLR NIIHWNLISA FILRNATWFV VQLTVSPEVH 
QSNVAWCRLV TAAYNYFHVT NFFWMFGEGC YLHTAIVLTY STDRLRKWMF VCIGWGVPFP 
IIVAWAIGKL HYDNEKCWFG KRPGVYTDYI YQGPMILVLL INFIFLFNIV RILMTKLRAS 
TTSETIQYRK AVKATLVLLP LLGITYMLFF VNPGEDEVSR VVFIYFNSFL ESFQGFFVSV 
FYCFLNSEVR SAIRKRWRRW QDKHSIRARV ARAMSIPTSP TRVSFHSIKQ STAV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Crhr1

Associated with

Other Information

Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor. PubMed ID: 8243338

Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain. PubMed ID: 8274282

The genomic structure of the rat corticotropin releasing factor receptor. A member of the class II G protein-coupled receptors. PubMed ID: 8662941