Slc30a1 | ENSRNOG00000004749 | NCBI 58976

Details for: Slc30a1

Gene ID: 58976

Symbol: Slc30a1

Ensembl ID: ENSRNOG00000004749

Description: solute carrier family 30 member 1

Associated with

Metal ion slc transporters
(R-RNO-425410)
Slc-mediated transmembrane transport
(R-RNO-425407)
Transport of bile salts and organic acids, metal ions and amine compounds
(R-RNO-425366)
Transport of small molecules
(R-RNO-382551)
Zinc efflux and compartmentalization by the slc30 family
(R-RNO-435368)
Zinc transporters
(R-RNO-435354)
Basolateral plasma membrane
(GO:0016323)
Cadmium ion transmembrane transport
(GO:0070574)
Calcium channel inhibitor activity
(GO:0019855)
Calcium ion import
(GO:0070509)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle membrane
(GO:0030659)
Defense response to bacterium
(GO:0042742)
Dendrite
(GO:0030425)
Detoxification of cadmium ion
(GO:0071585)
Detoxification of zinc ion
(GO:0010312)
Endoplasmic reticulum
(GO:0005783)
Glutamatergic postsynaptic density
(GO:0099573)
Golgi apparatus
(GO:0005794)
Intracellular calcium ion homeostasis
(GO:0006874)
Intracellular zinc ion homeostasis
(GO:0006882)
In utero embryonic development
(GO:0001701)
Metal ion binding
(GO:0046872)
Negative regulation of calcium ion import
(GO:0090281)
Negative regulation of neurotransmitter secretion
(GO:0046929)
Negative regulation of zinc ion transmembrane import
(GO:0071584)
Nuclear membrane
(GO:0031965)
Plasma membrane
(GO:0005886)
Positive regulation of dendritic spine morphogenesis
(GO:0061003)
Postsynaptic density, intracellular component
(GO:0099092)
Postsynaptic density membrane
(GO:0098839)
Regulation of postsynaptic density protein 95 clustering
(GO:1902897)
Schaffer collateral - ca1 synapse
(GO:0098685)
T-tubule
(GO:0030315)
Zinc:proton antiporter activity
(GO:0140826)
Zinc export across plasma membrane
(GO:0140882)
Zinc ion import into organelle
(GO:0062111)
Zinc ion transmembrane transport
(GO:0071577)
Zinc ion transmembrane transporter activity
(GO:0005385)
Zinc ion transport
(GO:0006829)

Other Information

Proteins

ZNT1_RAT

Genular Protein ID: 872454899

Symbol: ZNT1_RAT

Name: N/A

UniProtKB Accession Codes:

Q62720

Database IDs:

Citations:

PubMed ID: 7882967

Title: Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc.

PubMed ID: 7882967

DOI: 10.1002/j.1460-2075.1995.tb07042.x

PubMed ID: 9560190

Title: Regulation of the zinc transporter ZnT-1 by dietary zinc.

PubMed ID: 9560190

DOI: 10.1073/pnas.95.9.4841

PubMed ID: 15378655

Title: ZnT-1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc.

PubMed ID: 15378655

DOI: 10.1002/glia.20065

PubMed ID: 16741752

Title: Silencing of ZnT-1 expression enhances heavy metal influx and toxicity.

PubMed ID: 16741752

DOI: 10.1007/s00109-006-0062-4

PubMed ID: 19767393

Title: Molecular basis for zinc transporter 1 action as an endogenous inhibitor of L-type calcium channels.

PubMed ID: 19767393

DOI: 10.1074/jbc.m109.058842

PubMed ID: 19095042

Title: Silencing of ZnT1 reduces Zn2+ efflux in cultured cortical neurons.

PubMed ID: 19095042

DOI: 10.1016/j.neulet.2008.11.069

PubMed ID: 24951051

Title: ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger.

PubMed ID: 24951051

DOI: 10.1039/c4mt00108g

Sequence Information:

Length: 507
Mass: 55143
Checksum: 9F9770017C2455FC
Sequence:

MGCWGRNRGR LLCMLLLTFM FMVLEVVVSR VTASLAMLSD SFHMLSDVLA LVVALVAERF 
ARRTHATQKN TFGWIRAEVM GALVNAIFLT GLCFAILLEA VERFIEPHEM QQPLVVLSVG 
VAGLLVNVLG LCLFHHHSGE GQGAGHGHSH GHGHGHLAKG ARKAGRAGGE AGAPPGRAPD 
QEPDQEETNT LVANTSNSNG LKADQAEPEK LRSDDPVDVQ VNGNLIQESD SLESEDNRAG 
QLNMRGVFLH VLGDALGSVI VVVNALVFYF SWKGCTEDDF CVNPCFPDPC KSSVELMNST 
QAPMHEAGPC WVLYLDPTLC IIMVCILLYT TYPLLKESAL ILLQTVPKQI DIKHLVKELR 
DVEGVEEVHE LHVWQLAGSR IIATAHIKCE DPASYMQVAK TIKDVFHNHG IHATTIQPEF 
ASVGSKSSVV PCELACRTQC ALKQCCGTRP QVHSGKEAEK APTVSISCLE LSENLEKKPR 
RTKAEGSVPA VVIEIKNVPN KQPESSL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc30a1

Associated with

Other Information

Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. PubMed ID: 7882967

Regulation of the zinc transporter ZnT-1 by dietary zinc. PubMed ID: 9560190

ZnT-1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc. PubMed ID: 15378655

Silencing of ZnT-1 expression enhances heavy metal influx and toxicity. PubMed ID: 16741752

Molecular basis for zinc transporter 1 action as an endogenous inhibitor of L-type calcium channels. PubMed ID: 19767393

Silencing of ZnT1 reduces Zn2+ efflux in cultured cortical neurons. PubMed ID: 19095042

ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger. PubMed ID: 24951051