Details for: Ngly1
Associated with
Other Information
Genular Protein ID: 1418059280
Symbol: NGLY1_MOUSE
Name: Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10831608
Title: PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase.
PubMed ID: 10831608
PubMed ID: 12711318
Title: Ngly1, a mouse gene encoding a deglycosylating enzyme implicated in proteasomal degradation: expression, genomic organization, and chromosomal mapping.
PubMed ID: 12711318
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8021270
Title: Purification and enzymatic properties of peptide:N-glycanase from C3H mouse-derived L-929 fibroblast cells. Possible widespread occurrence of post-translational remodification of proteins by N-deglycosylation.
PubMed ID: 8021270
PubMed ID: 11562482
Title: Identification of proteins that interact with mammalian peptide:N-glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation.
PubMed ID: 11562482
PubMed ID: 12606569
Title: A role for N-glycanase in the cytosolic turnover of glycoproteins.
PubMed ID: 12606569
DOI: 10.1093/emboj/cdg107
PubMed ID: 15610852
Title: Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.
PubMed ID: 15610852
PubMed ID: 15358861
Title: A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins.
PubMed ID: 15358861
PubMed ID: 16055502
Title: The retrotranslocation protein derlin-1 binds peptide:N-glycanase to the endoplasmic reticulum.
PubMed ID: 16055502
PubMed ID: 16249333
Title: Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome.
PubMed ID: 16249333
PubMed ID: 16709668
Title: The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor.
PubMed ID: 16709668
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 16500903
Title: Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
PubMed ID: 16500903
Sequence Information:
- Length: 651
- Mass: 74275
- Checksum: F9D7A35726482F81
- Sequence:
MASATLGSSS SSASPAVAEL CQNTPETFLE ASKLLLTYAD NILRNPSDEK YRSIRIGNTA FSTRLLPVRG AVECLFEMGF EEGETHLIFP KKASVEQLQK IRDLIAIERS SRLDGSSKKV QFSQHPAAAK LPLEQSEDPA GLIRHSGNQT GQLPSLPSAP MVVGDSTILK VLQSNIQHVQ LYENPVLQEK ALTCIPVSEL KRKAQEKLFR ARKLDKGTNV SDEDFLLLEL LHWFKEEFFR WVNNIVCSKC GGETRSRDEA LLPNDDELKW GAKNVENHYC DACQLSNRFP RYNNPEKLLE TRCGRCGEWA NCFTLCCRAL GFEARYVWDY TDHVWTEVYS PSQQRWLHCD ACEDVCDKPL LYEIGWGKKL SYIIAFSKDE VVDVTWRYSC KHDEVMSRRT KVKEELLRET INGLNKQRQL SLSESRRKEL LQRIIVELVE FISPKTPRPG ELGGRVSGSL AWRVARGETG LERKEILFIP SENEKISKQF HLRYDIVRDR YIRVSDNNIN ISGWENGVWK MESIFRKVEK DWNMVYLARK EGSSFAYISW KFECGSAGLK VDTVSIRTSS QSFESGSVRW KLRSETAQVN LLGDKNLRSY NDFSGATEVT LEAELSRGDG DVAWQHTQLF RQSLNDSGEN GLEIIITFND L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.