Slc4a8 | ENSMUSG00000023032 | NCBI 59033

Details for: Slc4a8

Gene ID: 59033

Symbol: Slc4a8

Ensembl ID: ENSMUSG00000023032

Description: solute carrier family 4 (anion exchanger), member 8

Associated with

Bicarbonate transporters
(R-MMU-425381)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of inorganic cations/anions and amino acids/oligopeptides
(R-MMU-425393)
Transport of small molecules
(R-MMU-382551)
Antiporter activity
(GO:0015297)
Asymmetric synapse
(GO:0032279)
Axon terminus
(GO:0043679)
Basolateral plasma membrane
(GO:0016323)
Basolateral protein secretion
(GO:0110010)
Bicarbonate transmembrane transporter activity
(GO:0015106)
Bicarbonate transport
(GO:0015701)
Chloride transmembrane transport
(GO:1902476)
Chloride transmembrane transporter activity
(GO:0015108)
Cytoplasmic vesicle
(GO:0031410)
Dendrite
(GO:0030425)
Embryo development
(GO:0009790)
Glial cell projection
(GO:0097386)
Glutamatergic synapse
(GO:0098978)
Hippocampal mossy fiber
(GO:0097457)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Modulation of chemical synaptic transmission
(GO:0050804)
Monoatomic anion transmembrane transporter activity
(GO:0008509)
Monoatomic anion transport
(GO:0006820)
Monoatomic ion transport
(GO:0006811)
Neuronal cell body membrane
(GO:0032809)
Neuron projection
(GO:0043005)
Plasma membrane
(GO:0005886)
Positive regulation of synaptic vesicle exocytosis
(GO:2000302)
Presynapse
(GO:0098793)
Presynaptic membrane
(GO:0042734)
Regulation of intracellular ph
(GO:0051453)
Regulation of membrane potential
(GO:0042391)
Sodium,bicarbonate:chloride antiporter activity
(GO:0140892)
Sodium:bicarbonate symporter activity
(GO:0008510)
Sodium ion transmembrane transport
(GO:0035725)
Sodium ion transmembrane transporter activity
(GO:0015081)
Sodium ion transport
(GO:0006814)
Solute:inorganic anion antiporter activity
(GO:0005452)
Symmetric synapse
(GO:0032280)
Synapse
(GO:0045202)
Synaptic vesicle
(GO:0008021)
Synaptic vesicle membrane
(GO:0030672)
Terminal bouton
(GO:0043195)
Transmembrane transport
(GO:0055085)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Electroneutral sodium bicarbonate exchanger 1
Q3UR07_MOUSE

Genular Protein ID: 137480857

Symbol: S4A8_MOUSE

Name: Electroneutral sodium bicarbonate exchanger 1

UniProtKB Accession Codes:

Q8JZR6 Q3TAV7 Q6A004 Q8BYI7 Q9JKV6

Database IDs:

Citations:

PubMed ID: 11260402

Title: Mouse Na+: HCO3- cotransporter isoform NBC-3 (kNBC-3): cloning, expression, and renal distribution.

PubMed ID: 11260402

DOI: 10.1046/j.1523-1755.2001.0590041405.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15368895

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 15368895

DOI: 10.1093/dnares/11.3.205

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18359573

Title: Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNS.

PubMed ID: 18359573

DOI: 10.1016/j.neuroscience.2008.02.018

PubMed ID: 20389022

Title: The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice.

PubMed ID: 20389022

DOI: 10.1172/jci40145

PubMed ID: 21593314

Title: Synaptic glutamate release is modulated by the Na+ -driven Cl-/HCO(3)- exchanger Slc4a8.

PubMed ID: 21593314

DOI: 10.1523/jneurosci.0269-11.2011

PubMed ID: 30355950

Title: Slc4a8 in the Kidney: Expression, Subcellular Localization and Role in Salt Reabsorption.

PubMed ID: 30355950

DOI: 10.1159/000494596

Sequence Information:

Length: 1089
Mass: 122421
Checksum: CFAE127D3853DDD8
Sequence:

MPAGSNEPDG VLSYQRPDEE AVVDQGGTST ILNIHYEKEE LEGHRTLYVG VRMPLGRQSH 
RHHRTHGQKH RRRGGRGKGA SQGEEGLEAL AHDTPSQRVQ FILGTEEDEE HVPHELFTEL 
DEICMKEGED AEWKETARWL KFEEDVEDGG ERWSKPYVAT LSLHSLFELR SCLINGSVLL 
DMRASSIEEI SDLILDQQEL LRDLSDSVRV KVREALLKKH HHQNERRRNN LIPIVRSFAE 
VGKKQSDPHS MDRDGQTVSP QSATNLEVKN GVNCEHSPVD LSKVDLHFMK KIPTGAEASN 
VLVGEVDTLD RPIVAFVRLS PAVLLSGLTE VPIPTRFLFI LLGPVGKGQQ YHEIGRSMAT 
IMTDEIFHDV AYKAKERDDL LAGIDEFLDQ VTVLPPGEWD PSIRIEPPKN VPSQEKRKMP 
GVPNGNVCHI EPEPHGGHSG PELERTGRLF GGLVLDVKRK APWYWSDYRD ALSLQCLASF 
LFLYCACMSP VITFGGLLGE ATEGRISAIE SLFGASMTGI AYSLFAGQPL TILGSTGPVL 
VFEKILFKFC KDYALSYLSL RALIGLWTAF LCIVLVATDA SSLVCYITRF TEEAFASLIC 
IIFIYEAIEK LIHLAETYPI HMHSQLDHLS LYYCRCVLPE NPNNHTLQYW KDHNILAAEV 
NWANLTVSEC QEMHGEFMGS ACGHHGPYTP DVLFWSCILF FATFIVSSTL KTFKTSRYFP 
TRVRSMVSDF AVFLTIFTMV VLDFLIGVPS PKLQVPNVFK PTRDDRGWFI NPIGPNPWWT 
VIAAIIPALL CTILIFMDQQ ITAVIINRKE HKLKKGCGYH LDLLMVAVML GVCSIMGLPW 
FVAATVLSIT HVNSLKLESE CSAPGEQPKF LGIREQRVTG LMIFVLMGCS VFMTAVLKFI 
PMPVLYGVFL YMGVSSLQGI QFFDRLKLFG MPAKHQPDFI YLRHVPLRKV HLFTLVQLTC 
LVLLWVIKAS PAAIVFPMMV LALVFVRKVM DLCFSKRELS WLDDLMPESK KKKLDDAKKK 
EEEEAEKMLD IGGDKFPLES RKLLSSPGKS SSFRCDPSEI NISDEMPKTT VWKALSINSG 
NTKEKSPFN

Genular Protein ID: 2180278387

Symbol: Q3UR07_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UR07

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 134
Mass: 14407
Checksum: 9CA2C76686020B09
Sequence:

MRDIAVTNMR RHSSSKKHPW DEAPRAGHLQ GTPTHHSQAE LQAPGHTHPS QPSRAAGSRA 
HPPITAKQSC RLQGTPTHHC QAELQAPGHT HPSQPSRAAG WLQEAHLPTA APPAWRSPSL 
GGKNPTRSSS LCHS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc4a8

Associated with

Other Information

Mouse Na+: HCO3- cotransporter isoform NBC-3 (kNBC-3): cloning, expression, and renal distribution. PubMed ID: 11260402

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. PubMed ID: 15368895

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNS. PubMed ID: 18359573

The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice. PubMed ID: 20389022

Synaptic glutamate release is modulated by the Na+ -driven Cl-/HCO(3)- exchanger Slc4a8. PubMed ID: 21593314

Slc4a8 in the Kidney: Expression, Subcellular Localization and Role in Salt Reabsorption. PubMed ID: 30355950

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073