Nherf1 | ENSRNOG00000003232 | NCBI 59114

Details for: Nherf1

Gene ID: 59114

Symbol: Nherf1

Ensembl ID: ENSRNOG00000003232

Description: NHERF family PDZ scaffold protein 1

Associated with

Actin cytoskeleton organization
(GO:0030036)
Adenylate cyclase-activating dopamine receptor signaling pathway
(GO:0007191)
Apical part of cell
(GO:0045177)
Apical plasma membrane
(GO:0016324)
Auditory receptor cell stereocilium organization
(GO:0060088)
Beta-2 adrenergic receptor binding
(GO:0031698)
Beta-catenin binding
(GO:0008013)
Bile acid secretion
(GO:0032782)
Brush border membrane
(GO:0031526)
Cell periphery
(GO:0071944)
Cerebrospinal fluid circulation
(GO:0090660)
Channel activator activity
(GO:0099103)
Chloride channel regulator activity
(GO:0017081)
Cilium organization
(GO:0044782)
Cytoplasm
(GO:0005737)
Dopamine receptor binding
(GO:0050780)
Endomembrane system
(GO:0012505)
Establishment of epithelial cell apical/basal polarity
(GO:0045198)
Establishment of golgi localization
(GO:0051683)
Establishment of localization in cell
(GO:0051649)
Extracellular region
(GO:0005576)
Fibroblast migration
(GO:0010761)
Filopodium
(GO:0030175)
Gamma-aminobutyric acid import
(GO:0051939)
Gamma-aminobutyric acid transmembrane transporter activity
(GO:0015185)
Gland morphogenesis
(GO:0022612)
Glutathione transport
(GO:0034635)
Growth factor receptor binding
(GO:0070851)
Identical protein binding
(GO:0042802)
Import across plasma membrane
(GO:0098739)
Intracellular phosphate ion homeostasis
(GO:0030643)
Maintenance of epithelial cell apical/basal polarity
(GO:0045199)
Membrane
(GO:0016020)
Microvillus
(GO:0005902)
Microvillus assembly
(GO:0030033)
Microvillus membrane
(GO:0031528)
Molecular adaptor activity
(GO:0060090)
Myosin ii binding
(GO:0045159)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of cell motility
(GO:2000146)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of erk1 and erk2 cascade
(GO:0070373)
Negative regulation of fibroblast migration
(GO:0010764)
Negative regulation of mitotic cell cycle
(GO:0045930)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Negative regulation of platelet-derived growth factor receptor signaling pathway
(GO:0010642)
Negative regulation of sodium ion transport
(GO:0010766)
Nuclear migration
(GO:0007097)
Nucleus
(GO:0005634)
Pdz domain binding
(GO:0030165)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphatase binding
(GO:0019902)
Phospholipase c-activating dopamine receptor signaling pathway
(GO:0060158)
Plasma membrane organization
(GO:0007009)
Plasma membrane protein complex
(GO:0098797)
Positive regulation of intrinsic apoptotic signaling pathway
(GO:2001244)
Positive regulation of monoatomic ion transmembrane transport
(GO:0034767)
Protein-containing complex binding
(GO:0044877)
Protein-membrane adaptor activity
(GO:0043495)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein localization
(GO:0008104)
Protein localization to plasma membrane
(GO:0072659)
Protein self-association
(GO:0043621)
Regulation of cell shape
(GO:0008360)
Regulation of cell size
(GO:0008361)
Regulation of renal phosphate excretion
(GO:1903402)
Renal absorption
(GO:0070293)
Renal phosphate ion absorption
(GO:0097291)
Renal sodium ion transport
(GO:0003096)
Ruffle
(GO:0001726)
Sensory perception of sound
(GO:0007605)
Signaling receptor binding
(GO:0005102)
Sodium ion transport
(GO:0006814)
Sperm midpiece
(GO:0097225)
Stereocilium
(GO:0032420)
Stereocilium tip
(GO:0032426)
Transmembrane transporter binding
(GO:0044325)
Type 2 metabotropic glutamate receptor binding
(GO:0031799)
Type 3 metabotropic glutamate receptor binding
(GO:0031800)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Na(+)/H(+) exchange regulatory cofactor NHE-RF1

Genular Protein ID: 1802078251

Symbol: NHRF1_RAT

Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF1

UniProtKB Accession Codes:

Q9JJ19

Database IDs:

Citations:

PubMed ID: 10859298

Title: Evidence for ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) self-association through PDZ-PDZ interactions.

PubMed ID: 10859298

DOI: 10.1074/jbc.c000092200

PubMed ID: 11457882

Title: Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton.

PubMed ID: 11457882

DOI: 10.1172/jci12539

PubMed ID: 12444018

Title: The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.

PubMed ID: 12444018

DOI: 10.1152/ajpcell.00225.2002

PubMed ID: 16396499

Title: Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS.

PubMed ID: 16396499

DOI: 10.1021/pr0503073

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 356
Mass: 38830
Checksum: C562AEF5870B8E08
Sequence:

MSADAAAGEP LPRLCCLEKG PNGYGFHLHG EKGKVGQFIR LVEPGSPAEK SGLLAGDRLV 
EVNGENVEKE THQQVVSRIR AALNAVRLLV VDPETDEQLK KLGVPIREEL LRAQEKSEHT 
EPPAAADTKK AGDQNEAEKS HLERCELRPR LCTMKKGPNG YGFNLHSDKS KPGQFIRAVD 
PDSPAEASGL RAQDRIVEVN GVCMEGKQHG DVVSAIKAGG DEAKLLVVDK ETDEFFKKCR 
VTPSQEHLDG PLPEPFSNGE IQKENSREAL VEPASESPRP ALARSASSDT SEELNAQDSP 
KRHDSTEPSS TSSSSDPILD FNISLAVAKE RAHQKRSSKR APQMDWSKKN ELFSNL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nherf1

Associated with

Other Information

Evidence for ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) self-association through PDZ-PDZ interactions. PubMed ID: 10859298

Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton. PubMed ID: 11457882

The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction. PubMed ID: 12444018