Details for: SIGIRR

Gene ID: 59307

Symbol: SIGIRR

Ensembl ID: ENSG00000185187

Description: single Ig and TIR domain containing

Associated with

Other Information

Genular Protein ID: 4049569762

Symbol: SIGIR_HUMAN

Name: Single Ig IL-1-related receptor

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10346978

Title: Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily.

PubMed ID: 10346978

DOI: 10.1006/cyto.1998.0452

PubMed ID: 14715412

Title: Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR.

PubMed ID: 14715412

PubMed ID: 12925853

Title: SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.

PubMed ID: 12925853

DOI: 10.1038/ni968

PubMed ID: 15866876

Title: SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms.

PubMed ID: 15866876

DOI: 10.1074/jbc.m501363200

PubMed ID: 21077278

Title: Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation.

PubMed ID: 21077278

DOI: 10.1111/j.1365-2249.2010.04254.x

PubMed ID: 21187075

Title: A novel binding protein of single immunoglobulin IL-1 receptor-related molecule: Paralemmin-3.

PubMed ID: 21187075

DOI: 10.1016/j.bbrc.2010.12.104

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25963006

Title: SIGIRR genetic variants in premature infants with necrotizing enterocolitis.

PubMed ID: 25963006

DOI: 10.1542/peds.2014-3386

Sequence Information:

  • Length: 410
  • Mass: 45679
  • Checksum: BA4564C2ABAB5104
  • Sequence:
  • MPGVCDRAPD FLSPSEDQVL RPALGSSVAL NCTAWVVSGP HCSLPSVQWL KDGLPLGIGG 
    HYSLHEYSWV KANLSEVLVS SVLGVNVTST EVYGAFTCSI QNISFSSFTL QRAGPTSHVA 
    AVLASLLVLL ALLLAALLYV KCRLNVLLWY QDAYGEVEIN DGKLYDAYVS YSDCPEDRKF 
    VNFILKPQLE RRRGYKLFLD DRDLLPRAEP SADLLVNLSR CRRLIVVLSD AFLSRAWCSH 
    SFREGLCRLL ELTRRPIFIT FEGQRRDPAH PALRLLRQHR HLVTLLLWRP GSVTPSSDFW 
    KEVQLALPRK VQYRPVEGDP QTQLQDDKDP MLILRGRVPE GRALDSEVDP DPEGDLGVRG 
    PVFGEPSAPP HTSGVSLGES RSSEVDVSDL GSRNYSARTD FYCLVSKDDM

Genular Protein ID: 2692931204

Symbol: C9JFX4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 504
  • Mass: 55221
  • Checksum: C6A974A6C4ED30C8
  • Sequence:
  • MPGVCDRAPD FLSPSEDQVL RPALGSSVAL NCTAWVVSGP HCSLPSVQWL KDGLPLGIGG 
    HYSLHEYSWV KANLSEVLVS SVLGVNVTST EVYGAFTCSI QNISFSSFTL QRAGPTSHVA 
    AVLASLLVLL ALLLAALLYV KCRLNVLLWY QDAYGEVEIN DGKLYDAYVS YSDCPEDRKF 
    VNFILKPQLE RRRGYKLFLD DRDLLPRAEP SADLLVNLSR CRRLIVVLSD AFLSRAWCSH 
    SFREGLCRLL ELTRRPIFIT FEGQRRDPAH PALRLLRQHR HLVTLLLWRP GSVTPSSDFW 
    KEVQLALPRK VQYRPVEGDP QTQLQDDKDP MLILRGRVPE GRALDSEVDP DPEGDLGMPA 
    QPHSPTGEAQ HRAEWGQAQG TGPGGAPGVE DSSRHREPLH GLCPGGARPS VCLGTSWASQ 
    AITAGGEQGQ PLAVGLGQGC GWPPQASRSP HPRCPGACLW RAISSTAHQW GLAGREPEQR 
    SGRLGSRLAK LQCPHRLLLP GVQG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.