Details for: Kcnk1

Gene ID: 59324

Symbol: Kcnk1

Ensembl ID: ENSRNOG00000019937

Description: potassium two pore domain channel subfamily K member 1

Associated with

Other Information

Genular Protein ID: 1098458085

Symbol: KCNK1_RAT

Name: Potassium channel subfamily K member 1

UniProtKB Accession Codes:

Q9Z2T2

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CTD 1 EMBL 4 EMDB 2 Ensembl 4 GO 22 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PIRSF 1 PRINTS 3 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 2 Reactome 2 RefSeq 1 SAM 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9843722

Title: Expression of TWIK-1, a novel weakly inward rectifying potassium channel in rat kidney.

PubMed ID: 9843722

DOI: 10.1152/ajpcell.1998.275.6.c1602

PubMed ID: 11567039

Title: Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.

PubMed ID: 11567039

DOI: 10.1523/jneurosci.21-19-07491.2001

PubMed ID: 12855359

Title: Cellular localization of TWIK-1, a two-pore-domain potassium channel in the rodent inner ear.

PubMed ID: 12855359

DOI: 10.1016/s0378-5955(03)00162-x

PubMed ID: 17452494

Title: Serotonin inhibits neuronal excitability by activating two-pore domain K+ channels in the entorhinal cortex.

PubMed ID: 17452494

DOI: 10.1124/mol.107.034389

PubMed ID: 18838117

Title: Distribution of two-pore-domain potassium channels in the adult rat vestibular periphery.

PubMed ID: 18838117

DOI: 10.1016/j.heares.2008.09.004

PubMed ID: 19571146

Title: TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices.

PubMed ID: 19571146

DOI: 10.1523/jneurosci.5784-08.2009

PubMed ID: 22948150

Title: Acid-sensitive TWIK and TASK two-pore domain potassium channels change ion selectivity and become permeable to sodium in extracellular acidification.

PubMed ID: 22948150

DOI: 10.1074/jbc.m112.398164

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 23169818

Title: SUMOylation silences heterodimeric TASK potassium channels containing K2P1 subunits in cerebellar granule neurons.

PubMed ID: 23169818

DOI: 10.1126/scisignal.2003431

PubMed ID: 25305496

Title: Differential expression of two-pore domain potassium channels in rat cerebellar granule neurons.

PubMed ID: 25305496

DOI: 10.1016/j.bbrc.2014.10.012

PubMed ID: 25530075

Title: The family of K2P channels: salient structural and functional properties.

PubMed ID: 25530075

DOI: 10.1113/jphysiol.2014.287268

PubMed ID: 25339226

Title: Silent but not dumb: how cellular trafficking and pore gating modulate expression of TWIK1 and THIK2.

PubMed ID: 25339226

DOI: 10.1007/s00424-014-1631-y

Sequence Information:

  • Length: 336
  • Mass: 38228
  • Checksum: 5E78031947D75DE6
  • Sequence:
    • MLQSLAGSSC VRLVERHRSA WCFGFLVLGY LLYLVFGAVV FSSVELPYED LLRQELRKLK 
RRFLEEHECL SEPQLEQFLG RVLEASNYGV SVLSNASGNW NWDFTSALFF ASTVLSTTGY 
GHTVPLSDGG KAFCIIYSVI GIPFTLLFLT AVVQRVTVHV TRRPVLYFHI RWGFSKQVVA 
IVHAVLLGFV TVSCFFFIPA AVFSVLEDDW NFLESFYFCF ISLSTIGLGD YVPGEGYNQK 
FRELYKIGIT CYLLLGLIAM LVVLETFCEL HELKKFRKMF YVKKDKDEDQ VHIMEHDQLS 
FSSITEQAAG LKEEQKQNEP FVASQSPPYE DGSANH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.