Ereg | ENSRNOG00000002771 | NCBI 59325

Details for: Ereg

Gene ID: 59325

Symbol: Ereg

Ensembl ID: ENSRNOG00000002771

Description: epiregulin

Associated with

Cargo recognition for clathrin-mediated endocytosis
(R-RNO-8856825)
Clathrin-mediated endocytosis
(R-RNO-8856828)
Downregulation of erbb2 signaling
(R-RNO-8863795)
Egfr downregulation
(R-RNO-182971)
Egfr interacts with phospholipase c-gamma
(R-RNO-212718)
Erbb2 activates ptk6 signaling
(R-RNO-8847993)
Erbb2 regulates cell motility
(R-RNO-6785631)
Esr-mediated signaling
(R-RNO-8939211)
Extra-nuclear estrogen signaling
(R-RNO-9009391)
Gab1 signalosome
(R-RNO-180292)
Grb2 events in egfr signaling
(R-RNO-179812)
Grb2 events in erbb2 signaling
(R-RNO-1963640)
Intracellular signaling by second messengers
(R-RNO-9006925)
Mapk1/mapk3 signaling
(R-RNO-5684996)
Mapk family signaling cascades
(R-RNO-5683057)
Membrane trafficking
(R-RNO-199991)
Negative regulation of the pi3k/akt network
(R-RNO-199418)
Pi3k events in erbb2 signaling
(R-RNO-1963642)
Pi3k events in erbb4 signaling
(R-RNO-1250342)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-RNO-6811558)
Pip3 activates akt signaling
(R-RNO-1257604)
Raf/map kinase cascade
(R-RNO-5673001)
Shc1 events in egfr signaling
(R-RNO-180336)
Shc1 events in erbb2 signaling
(R-RNO-1250196)
Shc1 events in erbb4 signaling
(R-RNO-1250347)
Signaling by egfr
(R-RNO-177929)
Signaling by erbb2
(R-RNO-1227986)
Signaling by erbb4
(R-RNO-1236394)
Signaling by non-receptor tyrosine kinases
(R-RNO-9006927)
Signaling by nuclear receptors
(R-RNO-9006931)
Signaling by ptk6
(R-RNO-8848021)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Vesicle-mediated transport
(R-RNO-5653656)
Angiogenesis
(GO:0001525)
Cell-cell signaling
(GO:0007267)
Cytokine-mediated signaling pathway
(GO:0019221)
Epidermal growth factor receptor binding
(GO:0005154)
Epidermal growth factor receptor signaling pathway
(GO:0007173)
Erbb2-egfr signaling pathway
(GO:0038134)
Erbb2-erbb4 signaling pathway
(GO:0038135)
Erbb4-erbb4 signaling pathway
(GO:0038138)
Extracellular space
(GO:0005615)
Female meiotic nuclear division
(GO:0007143)
Growth factor activity
(GO:0008083)
Keratinocyte proliferation
(GO:0043616)
Luteinizing hormone signaling pathway
(GO:0042700)
Membrane
(GO:0016020)
Mrna transcription
(GO:0009299)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of smooth muscle cell differentiation
(GO:0051151)
Oocyte maturation
(GO:0001556)
Ovarian cumulus expansion
(GO:0001550)
Ovulation
(GO:0030728)
Plasma membrane
(GO:0005886)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytokine production
(GO:0001819)
Positive regulation of dna replication
(GO:0045740)
Positive regulation of fibroblast proliferation
(GO:0048146)
Positive regulation of innate immune response
(GO:0045089)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of mitotic nuclear division
(GO:0045840)
Positive regulation of phosphorylation
(GO:0042327)
Positive regulation of smooth muscle cell proliferation
(GO:0048661)
Primary follicle stage
(GO:0048160)
Receptor ligand activity
(GO:0048018)
Response to peptide hormone
(GO:0043434)
Signal transduction
(GO:0007165)
Transmembrane receptor protein tyrosine kinase activator activity
(GO:0030297)

Other Information

Proteins

Proepiregulin

Genular Protein ID: 2598233502

Symbol: EREG_RAT

Name: Proepiregulin

UniProtKB Accession Codes:

Q9Z0L5

Database IDs:

Citations:

PubMed ID: 9990076

Title: Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombin.

PubMed ID: 9990076

DOI: 10.1073/pnas.96.4.1633

PubMed ID: 12446600

Title: Transcriptional regulation of the epiregulin gene in the rat ovary.

PubMed ID: 12446600

DOI: 10.1210/en.2002-220440

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 24631357

Title: Epiregulin: roles in normal physiology and cancer.

PubMed ID: 24631357

DOI: 10.1016/j.semcdb.2014.03.005

Sequence Information:

Length: 162
Mass: 18404
Checksum: EA660DE2B34990C4
Sequence:

METFPAAWVL ALLCLGSHLL QAVISTTVIP SCIPEESEDN CTALVQMEDD PRVAQVLITK 
CSSDMDGYCL HGHCIYLVDM SEKYCRCEVG YTGLRCEHFF LTVHQPLSRE YVALTVILVF 
LFLIVTAGSM YYFCRWYRNR KSKKSREEYE RVTSGGPGLP QV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ereg

Associated with

Other Information

Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombin. PubMed ID: 9990076

Transcriptional regulation of the epiregulin gene in the rat ovary. PubMed ID: 12446600

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. PubMed ID: 15057822

Epiregulin: roles in normal physiology and cancer. PubMed ID: 24631357

Database document:

PubMed ID: 9990076

PubMed ID: 12446600

PubMed ID: 15057822

PubMed ID: 24631357