ZNF350 | ENSG00000256683 | NCBI 59348

Details for: ZNF350

Gene ID: 59348

Symbol: ZNF350

Ensembl ID: ENSG00000256683

Description: zinc finger protein 350

Associated with

Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Rna polymerase ii transcription
(R-HSA-73857)
Sumo e3 ligases sumoylate target proteins
(R-HSA-3108232)
Sumoylation
(R-HSA-2990846)
Sumoylation of transcription cofactors
(R-HSA-3899300)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Metal ion binding
(GO:0046872)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear body
(GO:0016604)
Nuclear matrix
(GO:0016363)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii intronic transcription regulatory region sequence-specific dna binding
(GO:0001162)
Transcription repressor complex
(GO:0017053)

Other Information

Proteins

Zinc finger protein 350

Genular Protein ID: 3643388054

Symbol: ZN350_HUMAN

Name: Zinc finger protein 350

UniProtKB Accession Codes:

Q9GZX5 Q96G73 Q9HAQ4

Database IDs:

Citations:

PubMed ID: 11090615

Title: Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1.

PubMed ID: 11090615

DOI: 10.1016/s1097-2765(00)00075-7

PubMed ID: 11161714

Title: Characterization of a novel zinc finger gene with increased expression in nondividing normal human cells.

PubMed ID: 11161714

DOI: 10.1006/excr.2000.5068

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 23665872

Title: Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.

PubMed ID: 23665872

DOI: 10.1007/s00018-013-1359-4

PubMed ID: 12872252

Title: Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families and among early-onset breast cancer cases and reference individuals.

PubMed ID: 12872252

DOI: 10.1002/humu.10238

PubMed ID: 14755250

Title: An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.

PubMed ID: 14755250

DOI: 10.1038/sj.onc.1207319

Sequence Information:

Length: 532
Mass: 60011
Checksum: FEF12A92F95BAC8A
Sequence:

MIQAQESITL EDVAVDFTWE EWQLLGAAQK DLYRDVMLEN YSNLVAVGYQ ASKPDALFKL 
EQGEQLWTIE DGIHSGACSD IWKVDHVLER LQSESLVNRR KPCHEHDAFE NIVHCSKSQF 
LLGQNHDIFD LRGKSLKSNL TLVNQSKGYE IKNSVEFTGN GDSFLHANHE RLHTAIKFPA 
SQKLISTKSQ FISPKHQKTR KLEKHHVCSE CGKAFIKKSW LTDHQVMHTG EKPHRCSLCE 
KAFSRKFMLT EHQRTHTGEK PYECPECGKA FLKKSRLNIH QKTHTGEKPY ICSECGKGFI 
QKGNLIVHQR IHTGEKPYIC NECGKGFIQK TCLIAHQRFH TGKTPFVCSE CGKSCSQKSG 
LIKHQRIHTG EKPFECSECG KAFSTKQKLI VHQRTHTGER PYGCNECGKA FAYMSCLVKH 
KRIHTREKQE AAKVENPPAE RHSSLHTSDV MQEKNSANGA TTQVPSVAPQ TSLNISGLLA 
NRNVVLVGQP VVRCAASGDN RGFAQDRNLV NAVNVVVPSV INYVLFYVTE NP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ZNF350

Associated with

Other Information

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1. PubMed ID: 11090615

Characterization of a novel zinc finger gene with increased expression in nondividing normal human cells. PubMed ID: 11161714

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1. PubMed ID: 23665872

Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families and among early-onset breast cancer cases and reference individuals. PubMed ID: 12872252

An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein. PubMed ID: 14755250