Details for: Mark2
Associated with
Other Information
Genular Protein ID: 2550943348
Symbol: MARK2_RAT
Name: Serine/threonine-protein kinase MARK2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9108484
Title: MARK - a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.
PubMed ID: 9108484
PubMed ID: 14517247
Title: MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1.
PubMed ID: 14517247
DOI: 10.1093/emboj/cdg447
PubMed ID: 15466480
Title: MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons.
PubMed ID: 15466480
PubMed ID: 14741102
Title: Doublecortin microtubule affinity is regulated by a balance of kinase and phosphatase activity at the leading edge of migrating neurons.
PubMed ID: 14741102
PubMed ID: 16257959
Title: GSK-3beta directly phosphorylates and activates MARK2/PAR-1.
PubMed ID: 16257959
PubMed ID: 16014608
Title: PAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin.
PubMed ID: 16014608
PubMed ID: 16717194
Title: Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity.
PubMed ID: 16717194
PubMed ID: 17442826
Title: A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth.
PubMed ID: 17442826
PubMed ID: 18424437
Title: Glycogen synthase kinase (GSK) 3beta directly phosphorylates Serine 212 in the regulatory loop and inhibits microtubule affinity-regulating kinase (MARK) 2.
PubMed ID: 18424437
PubMed ID: 18509032
Title: Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration.
PubMed ID: 18509032
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
DOI: 10.1038/ncomms1871
PubMed ID: 16472737
Title: Structure of the catalytic and ubiquitin-associated domains of the protein kinase MARK/Par-1.
PubMed ID: 16472737
PubMed ID: 20071654
Title: Structure and function of polarity-inducing kinase family MARK/Par-1 within the branch of AMPK/Snf1-related kinases.
PubMed ID: 20071654
DOI: 10.1096/fj.09-148064
Sequence Information:
- Length: 722
- Mass: 80872
- Checksum: 2CBAFD1C38007ECC
- Sequence:
MSSARTPLPT LNERDTEQPT LGHLDSKPSS KSNMLRGRNS ATSADEQPHI GNYRLLKTIG KGNFAKVKLA RHILTGKEVA VKIIDKTQLN SSSLQKLFRE VRIMKVLNHP NIVKLFEVIE TEKTLYLVME YASGGEVFDY LVAHGRMKEK EARAKFRQIV SAVQYCHQKF IVHRDLKAEN LLLDADMNIK IADFGFSNEF TFGNKLDTFC GSPPYAAPEL FQGKKYDGPE VDVWSLGVIL YTLVSGSLPF DGQNLKELRE RVLRGKYRIP FYMSTDCENL LKKFLILNPS KRGTLEQIMK DRWMNVGHED DELKPYVEPL PDYKDPRRTE LMVSMGYTRE EIQDSLVGQR YNEVMATYLL LGYKSSELEG DTITLKPRPS ADLTNSSAPS PSHKVQRSVS ANPKQRRSSD QAVPAIPTSN SYSKKTQSNN AENKRPEEET GRKASSTAKV PASPLPGLDR KKTTPTPSTN SVLSTSTNRS RNSPLLDRAS LGQASIQNGK DSTAPQRVPV ASPSAHNISS SSGAPDRTNF PRGVSSRSTF HAGQLRQVRD QQNLPFGVTP ASPSGHSQGR RGASGSIFSK FTSKFVRRNL NEPESKDRVE TLRPHVVGGG GTDKEKEEFR EAKPRSLRFT WSMKTTSSME PNEMMREIRK VLDANSCQSE LHERYMLLCV HGTPGHENFV QWEMEVCKLP RLSLNGVRFK RISGTSMAFK NIASKIANEL KL
Genular Protein ID: 742438276
Symbol: A0A0G2K6X6_RAT
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15057822
Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
PubMed ID: 15057822
DOI: 10.1038/nature02426
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
Sequence Information:
- Length: 785
- Mass: 87502
- Checksum: 236E1626A96FEDAD
- Sequence:
MSSARTPLPT LNERDTEQPT LGHLDSKPSS KSNMLRGRNS ATSADEQPHI GNYRLLKTIG KGNFAKVKLA RHILTGKEVA VKIIDKTQLN SSSLQKLFRE VRIMKVLNHP NIVKLFEVIE TEKTLYLVME YASGGEVFDY LVAHGRMKEK EARAKFRQIV SAVQYCHQKF IVHRDLKAEN LLLDADMNIK IADFGFSNEF TFGNKLDTFC GSPPYAAPEL FQGKKYDGPE VDVWSLGVIL YTLVSGSLPF DGQNLKELRE RVLRGKYRIP FYMSTDCENL LKKFLILNPS KRGTLEQIMK DRWMNVGHED DELKPYVEPL PDYKDPRRTE LMVSMGYTRE EIQDSLVGQR YNEVMATYLL LGYKSSELEG DTITLKPRPS ADLTNSSAPS PSHKVQRSVS ANPKQRRSSD QAVPAIPTSN SYSKKTQSNN AENKRPEEET GRKASSTAKV PASPLPGLDR KKTTPTPSTN SVLSTSTNRS RNSPLLDRAS LGQASIQNGK DSLTMPGSRA STASASAAVS AARPRQHQKS MSASVHPNKA SGLPPTESNC EVPRPSTAPQ RVPVASPSAH NISSSSGAPD RTNFPRGVSS RSTFHAGQLR QVRDQQNLPF GVTPASPSGH SQGRRGASGS IFSKFTSKFV RRNLSFRFAR RNLNEPESKD RVETLRPHVV GGGGTDKEKE EFREAKPRSL RFTWSMKTTS SMEPNEMMRE IRKVLDANSC QSELHERYML LCVHGTPGHE NFVQWEMEVC KLPRLSLNGV RFKRISGTSM AFKNIASKIA NELKL
Genular Protein ID: 3468674912
Symbol: A0A8I5Y7M0_RAT
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15057822
Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
PubMed ID: 15057822
DOI: 10.1038/nature02426
Sequence Information:
- Length: 841
- Mass: 94015
- Checksum: D1D844D802743709
- Sequence:
MSSARTPLPT LNERDTEQPT LGHLDSKPSS KSNMLRGRNS ATSADEQPHI GNYRLLKTIG KGNFAKVKLA RHILTGKEVA VKIIDKTQLN SSSLQKLFRE VRIMKVLNHP NIVKLFEVIE TEKTLYLVME YASGGEVFDY LVAHGRMKEK EARAKFRQIV SAVQYCHQKF IVHRDLKAEN LLLDADMNIK IADFGFSNEF TFGNKLDTFC GSPPYAAPEL FQGKKYDGPE VDVWSLGVIL YTLVSGSLPF DGQNLKELRE RVLRGKYRIP FYMSTDCENL LKKFLILNPS KRGTLEQIMK DRWMNVGHED DELKPYVEPL PDYKDPRRTE LMVSMGYTRE EIQDSLVGQR YNEVMATYLL LGYKSSELEG DTITLKPRPS ADLTNSSAPS PSHKVQRSVS ANPKQRRSSD QAVPAIPTSN SYSKKTQSNN AENKRPEEET GRKASSTAKV PASPLPGLDR KKTTPTPSTN SVLSTSTNRS RNSPLLDRAS LGQASIQNGK DSLTMPGSRA STASASAAVS AARPRQHQKS MSASVHPNKA SGLPPTESNC EVPRPSTAPQ RVPVASPSAH NISSSSGAPD RTNFPRGVSS RSTFHAGQLR QVRDQQNLPF GVTPASPSGH SQGRRGASGS IFSKFTSKFV RRNLSFRFAR RCRLSLPKSQ ELDILRQGSF CRQALVEQQE AHTLLLHLPS WDRAWLVQPG HVLCRPRNLN EPESKDRVET LRPHVVGGGG TDKEKEEFRE AKPRSLRFTW SMKTTSSMEP NEMMREIRKV LDANSCQSEL HERYMLLCVH GTPGHENFVQ WEMEVCKLPR LSLNGVRFKR ISGTSMAFKN IASKIANELK L
Genular Protein ID: 3469034370
Symbol: A0A8I6GJH6_RAT
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15057822
Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
PubMed ID: 15057822
DOI: 10.1038/nature02426
Sequence Information:
- Length: 707
- Mass: 79090
- Checksum: A037DA2DA7751213
- Sequence:
MSSARTPLPT LNERDTEQPT LGHLDSKPSS KSNMLRGRNS ATSADEQPHI GNYRLLKTIG KGNFAKVKLA RHILTGKEVA VKIIDKTQLN SSSLQKLFRE VRIMKVLNHP NIVKLFEVIE TEKTLYLVME YASGGEVFDY LVAHGRMKEK EARAKFRQIV SAVQYCHQKF IVHRDLKAEN LLLDADMNIK IADFGFSNEF TFGNKLDTFC GSPPYAAPEL FQGKKYDGPE VDVWSLGVIL YTLVSGSLPF DGQNLKELRE RVLRGKYRIP FYMSTDCENL LKKFLILNPS KRGTLEQIMK DRWMNVGHED DELKPYVEPL PDYKDPRRTE LMVSMGYTRE EIQDSLVGQR YNEVMATYLL LGYKSSELEG DTITLKPRPS ADLTNSSAPS PSHKVQRSVS ANPKQRRSSD QAVPAIPTSN SYSKKTQSNN AENKRPEEET GRKASSTAKV PASPLPGLDR KKTTPTPSTN SVLSTSTNRS RNSPLLDRAS LGQASIQNGK DSTAPQRVPV ASPSAHNISS SSGAPDRTNF PRGVSSRSTF HAGQLRQVRD QQNLPFGVTP ASPSGHSQGR RGASGSIFSK FTSKFVRRPH VVGGGGTDKE KEEFREAKPR SLRFTWSMKT TSSMEPNEMM REIRKVLDAN SCQSELHERY MLLCVHGTPG HENFVQWEME VCKLPRLSLN GVRFKRISGT SMAFKNIASK IANELKL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.