Cd14 | ENSRNOG00000017819 | NCBI 60350

Details for: Cd14

Gene ID: 60350

Symbol: Cd14

Ensembl ID: ENSRNOG00000017819

Description: CD14 molecule

Associated with

Activation of irf3, irf7 mediated by tbk1, ikbke
(R-RNO-936964)
Apoptosis
(R-RNO-109581)
Caspase activation via death receptors in the presence of ligand
(R-RNO-140534)
Caspase activation via extrinsic apoptotic signalling pathway
(R-RNO-5357769)
Ikk complex recruitment mediated by rip1
(R-RNO-937041)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Irak2 mediated activation of tak1 complex upon tlr7/8 or 9 stimulation
(R-RNO-975163)
Myd88 dependent cascade initiated on endosome
(R-RNO-975155)
Myd88-independent tlr4 cascade
(R-RNO-166166)
Neutrophil degranulation
(R-RNO-6798695)
Programmed cell death
(R-RNO-5357801)
Regulation of tlr by endogenous ligand
(R-RNO-5686938)
Toll-like receptor cascades
(R-RNO-168898)
Toll like receptor 4 (tlr4) cascade
(R-RNO-166016)
Toll like receptor 7/8 (tlr7/8) cascade
(R-RNO-168181)
Toll like receptor 9 (tlr9) cascade
(R-RNO-168138)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-RNO-975138)
Traf6-mediated induction of tak1 complex within tlr4 complex
(R-RNO-937072)
Transfer of lps from lbp carrier to cd14
(R-RNO-166020)
Trif(ticam1)-mediated tlr4 signaling
(R-RNO-937061)
Trif-mediated programmed cell death
(R-RNO-2562578)
Cell surface
(GO:0009986)
Cell surface pattern recognition receptor signaling pathway
(GO:0002752)
Cellular response to diacyl bacterial lipopeptide
(GO:0071726)
Cellular response to lipopolysaccharide
(GO:0071222)
Cellular response to lipoteichoic acid
(GO:0071223)
Cellular response to triacyl bacterial lipopeptide
(GO:0071727)
External side of plasma membrane
(GO:0009897)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Inflammatory response
(GO:0006954)
Innate immune response
(GO:0045087)
Lipopolysaccharide-mediated signaling pathway
(GO:0031663)
Lipopolysaccharide binding
(GO:0001530)
Lipopolysaccharide immune receptor activity
(GO:0001875)
Lipopolysaccharide receptor complex
(GO:0046696)
Lipoteichoic acid binding
(GO:0070891)
Membrane raft
(GO:0045121)
Positive regulation of cytokine production
(GO:0001819)
Positive regulation of endocytosis
(GO:0045807)
Positive regulation of interleukin-8 production
(GO:0032757)
Positive regulation of lipopolysaccharide-mediated signaling pathway
(GO:0031666)
Positive regulation of toll-like receptor 4 signaling pathway
(GO:0034145)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Positive regulation of type ii interferon production
(GO:0032729)
Positive regulation of type i interferon production
(GO:0032481)
Protein binding
(GO:0005515)
Receptor-mediated endocytosis
(GO:0006898)
Response to bacterium
(GO:0009617)
Response to electrical stimulus
(GO:0051602)
Response to ethanol
(GO:0045471)
Response to lipopolysaccharide
(GO:0032496)
Response to magnesium ion
(GO:0032026)
Response to molecule of bacterial origin
(GO:0002237)
Response to tumor necrosis factor
(GO:0034612)
Toll-like receptor 4 signaling pathway
(GO:0034142)

Other Information

Proteins

Monocyte differentiation antigen CD14

Genular Protein ID: 2071673807

Symbol: CD14_RAT

Name: Monocyte differentiation antigen CD14

UniProtKB Accession Codes:

Q63691 Q6GT04

Database IDs:

Citations:

PubMed ID: 8598386

Title: CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells.

PubMed ID: 8598386

DOI: 10.1016/0165-5728(95)00143-3

PubMed ID: 9201265

Title: Primary structure of rat CD14 and characteristics of rat CD14, cytokine, and NO synthase mRNA expression in mononuclear phagocyte system cells in response to LPS.

PubMed ID: 9201265

DOI: 10.1002/jlb.61.6.736

PubMed ID: 9784508

Title: Expression of CD14 by hepatocytes: upregulation by cytokines during endotoxemia.

PubMed ID: 9784508

DOI: 10.1128/iai.66.11.5089-5098.1998

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 372
Mass: 40054
Checksum: E99DD2C551DBBE69
Sequence:

MKLMLGLLLL PLTLVHASPA TPEPCELDQD EESVRCYCNF SDPQPNWSSA FLCAGAEDVE 
FYGGGRSLEY LLKRVDTEAN LGQYTDIIRS LPLKRLTVRS ARVPTQILFG TLRVLGYSGL 
RELTLENLEV TGTALSPLLD ATGPDLNTLS LRNVSWATTD TWLAELQQWL KPGLKVLSIA 
QAHSLNFSCK QVGVFPALAT LDLSDNPELG EKGLISALCP HKFPTLQVLA LRNAGMETTS 
GVCSALAAAR VPLQALDLSH NSLRDTAGTP SCDWPSQLNS LNLSFTGLEH VPKGLPAKLS 
VLDLSYNRLD RKPRPEELPE VGSLSLTGNP FLHSESQSEA YNSGVVIATA LSPGSAGLSG 
TLALLLGHRL FV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cd14

Associated with

Other Information

CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells. PubMed ID: 8598386

Primary structure of rat CD14 and characteristics of rat CD14, cytokine, and NO synthase mRNA expression in mononuclear phagocyte system cells in response to LPS. PubMed ID: 9201265

Expression of CD14 by hepatocytes: upregulation by cytokines during endotoxemia. PubMed ID: 9784508

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 8598386

PubMed ID: 9201265

PubMed ID: 9784508

PubMed ID: 15489334