Iigp1 | ENSMUSG00000054072 | NCBI 60440

Details for: Iigp1

Gene ID: 60440

Symbol: Iigp1

Ensembl ID: ENSMUSG00000054072

Description: interferon inducible GTPase 1

Associated with

Cellular response to interferon-beta
(GO:0035458)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytoplasm
(GO:0005737)
Defense response
(GO:0006952)
Defense response to gram-negative bacterium
(GO:0050829)
Defense response to protozoan
(GO:0042832)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Gdp binding
(GO:0019003)
Golgi apparatus
(GO:0005794)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Membrane
(GO:0016020)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of autophagy
(GO:0010506)
Response to bacterium
(GO:0009617)
Symbiont-containing vacuole membrane
(GO:0020005)

Other Information

Proteins

Interferon-inducible GTPase 1

Genular Protein ID: 1658052632

Symbol: IIGP1_MOUSE

Name: Interferon-inducible GTPase 1

UniProtKB Accession Codes:

Q9QZ85 Q9Z1M3

Database IDs:

Citations:

PubMed ID: 9862701

Title: Two families of GTPases dominate the complex cellular response to IFN-gamma.

PubMed ID: 9862701

PubMed ID: 11907101

Title: The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis.

PubMed ID: 11907101

DOI: 10.4049/jimmunol.168.7.3428

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15075236

Title: IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3.

PubMed ID: 15075236

DOI: 10.1242/jcs.01039

PubMed ID: 15294976

Title: Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis.

PubMed ID: 15294976

DOI: 10.4049/jimmunol.173.4.2594

PubMed ID: 16304607

Title: Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

PubMed ID: 16304607

DOI: 10.1371/journal.ppat.0010024

PubMed ID: 18772884

Title: Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii.

PubMed ID: 18772884

DOI: 10.1038/emboj.2008.176

PubMed ID: 18784077

Title: Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo.

PubMed ID: 18784077

DOI: 10.1074/jbc.m804846200

PubMed ID: 19242543

Title: IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy.

PubMed ID: 19242543

DOI: 10.1371/journal.pone.0004588

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 12732635

Title: IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization.

PubMed ID: 12732635

DOI: 10.1074/jbc.m211973200

Sequence Information:

Length: 413
Mass: 47572
Checksum: 44B5A95FCA58A37A
Sequence:

MGQLFSSPKS DENNDLPSSF TGYFKKFNTG RKIISQEILN LIELRMRKGN IQLTNSAISD 
ALKEIDSSVL NVAVTGETGS GKSSFINTLR GIGNEEEGAA KTGVVEVTME RHPYKHPNIP 
NVVFWDLPGI GSTNFPPNTY LEKMKFYEYD FFIIISATRF KKNDIDIAKA ISMMKKEFYF 
VRTKVDSDIT NEADGKPQTF DKEKVLQDIR LNCVNTFREN GIAEPPIFLL SNKNVCHYDF 
PVLMDKLISD LPIYKRHNFM VSLPNITDSV IEKKRQFLKQ RIWLEGFAAD LVNIIPSLTF 
LLDSDLETLK KSMKFYRTVF GVDETSLQRL ARDWEIEVDQ VEAMIKSPAV FKPTDEETIQ 
ERLSRYIQEF CLANGYLLPK NSFLKEIFYL KYYFLDMVTE DAKTLLKEIC LRN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Iigp1

Associated with

Other Information

Two families of GTPases dominate the complex cellular response to IFN-gamma. PubMed ID: 9862701

The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis. PubMed ID: 11907101

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3. PubMed ID: 15075236

Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis. PubMed ID: 15294976

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases. PubMed ID: 16304607

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii. PubMed ID: 18772884

Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo. PubMed ID: 18784077

IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy. PubMed ID: 19242543

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization. PubMed ID: 12732635