Details for: Kcnt1

Gene ID: 60444

Symbol: Kcnt1

Ensembl ID: ENSRNOG00000017283

Description: potassium sodium-activated channel subfamily T member 1

Associated with

Other Information

Genular Protein ID: 2656305235

Symbol: KCNT1_RAT

Name: Potassium channel subfamily T member 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10196543

Title: Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits.

PubMed ID: 10196543

DOI: 10.1038/2176

PubMed ID: 12442315

Title: Localization of the Slack potassium channel in the rat central nervous system.

PubMed ID: 12442315

DOI: 10.1002/cne.10439

PubMed ID: 12628167

Title: The sodium-activated potassium channel is encoded by a member of the Slo gene family.

PubMed ID: 12628167

DOI: 10.1016/s0896-6273(03)00096-5

PubMed ID: 16045448

Title: Identification and functional characterization of cereblon as a binding protein for large-conductance calcium-activated potassium channel in rat brain.

PubMed ID: 16045448

DOI: 10.1111/j.1471-4159.2005.03344.x

PubMed ID: 16687497

Title: Opposite regulation of Slick and Slack K+ channels by neuromodulators.

PubMed ID: 16687497

DOI: 10.1523/jneurosci.3372-05.2006

PubMed ID: 20512134

Title: Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.

PubMed ID: 20512134

DOI: 10.1038/nn.2563

PubMed ID: 23086397

Title: De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy.

PubMed ID: 23086397

DOI: 10.1038/ng.2441

PubMed ID: 24463883

Title: Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis.

PubMed ID: 24463883

DOI: 10.1093/hmg/ddu030

Sequence Information:

  • Length: 1237
  • Mass: 139615
  • Checksum: E11B4A7A77EB612B
  • Sequence:
  • MARAKLPRSP SEGKAGPGDT PAGSAAPEEP HGLSPLLPTR GGGSVGSDVG QRLHVEDFSL 
    DSSLSQVQVE FYVNENTFKE RLKLFFIKNQ RSSLRIRLFN FSLKLLTCLL YIVRVLLDNP 
    DQGIGCWGCT KYNYTFNGSS SEFHWAPILW VERKMALWVI QVIVATISFL ETMLLIYLSY 
    KGNIWEQIFH VSFVLEMINT LPFIITVFWP PLRNLFIPVF LNCWLAKHAL ENMINDFHRA 
    ILRTQSAMFN QVLILFCTLL CLVFTGTCGI QHLERAGGNL NLLTSFYFCI VTFSTVGFGD 
    VTPKIWPSQL LVVILICVTL VVLPLQFEEL VYLWMERQKS GGNYSRHRAR TEKHVVLCVS 
    SLKIDLLMDF LNEFYAHPRL QDYYVVILCP SEMDVQVRRV LQIPLWSQRV IYLQGSALKD 
    QDLMRAKMDN GEACFILSSR NEVDRTAADH QTILRAWAVK DFAPNCPLYV QILKPENKFH 
    VKFADHVVCE EECKYAMLAL NCICPATSTL ITLLVHTSRG QEGQESPEQW QRMYGRCSGN 
    EVYHIRMGDS KFFREYEGKS FTYAAFHAHK KYGVCLIGLK REENKSILLN PGPRHILAAS 
    DTCFYINITK EENSAFIFKQ EEKQNRRGLA GQALYEGPSR LPVHSIIASM VAMDLQNTDC 
    RPSQGGSGGG GGKLTLPTEN GSGSRRPSIA PVLELADSSA LLPCDLLSDQ SEDEVTPSDD 
    EGLSVVEYVK GYPPNSPYIG SSPTLCHLLP VKAPFCCLRL DKGCKHNSYE DAKAYGFKNK 
    LIIVSAETAG NGLYNFIVPL RAYYRSRREL NPIVLLLDNK PDHHFLEAIC CFPMVYYMEG 
    SVDNLDSLLQ CGIIYADNLV VVDKESTMSA EEDYMADAKT IVNVQTMFRL FPSLSITTEL 
    THPSNMRFMQ FRAKDSYSLA LSKLEKQERE NGSNLAFMFR LPFAAGRVFS ISMLDTLLYQ 
    SFVKDYMITI TRLLLGLDTT PGSGYLCAMK VTEDDLWIRT YGRLFQKLCS SSAEIPIGIY 
    RTECHVFSSE PHDLRAQSQI SVNMEDCEDT REAKGPWGTR AASGGGSTHG RHGGSADPVE 
    HPLLRRKSLQ WARKLSRKSS KQAGKAPMTT DWITQQRLSL YRRSERQELS ELVKNRMKHL 
    GLPTTGYEDV ANLTASDVMN RVNLGYLQDE MNDHHQNTLS YVLINPPPDT RLEPNDIVYL 
    IRSDPLAHVT SSSQSRKSSC SNKLSSCNPE TRDETQL

Genular Protein ID: 2633603095

Symbol: A0A8I6ALJ8_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 1219
  • Mass: 138558
  • Checksum: C25E4AD69A165A4E
  • Sequence:
  • MNDLDTEVLP LPPRYRFRDL LLGDQTFPND DRLHVEDFSL DSSLSQVQVE FYVNENTFKE 
    RLKLFFIKNQ RSSLRIRLFN FSLKLLTCLL YIVRVLLDNP DQGIGCWGCT KYNYTFNGSS 
    SEFHWAPILW VERKMALWVI QVIVATISFL ETMLLIYLSY KGNIWEQIFH VSFVLEMINT 
    LPFIITVFWP PLRNLFIPVF LNCWLAKHAL ENMINDFHRA ILRTQSAMFN QVLILFCTLL 
    CLVFTGTCGI QHLERAGGNL NLLTSFYFCI VTFSTVGFGD VTPKIWPSQL LVVILICVTL 
    VVLPLQFEEL VYLWMERQKS GGNYSRHRAR TEKHVVLCVS SLKIDLLMDF LNEFYAHPRL 
    QDYYVVILCP SEMDVQVRRV LQIPLWSQRV IYLQGSALKD QDLMRAKMDN GEACFILSSR 
    NEVDRTAADH QTILRAWAVK DFAPNCPLYV QILKPENKFH VKFADHVVCE EECKYAMLAL 
    NCICPATSTL ITLLVHTSRG QEGQESPEQW QRMYGRCSGN EVYHIRMGDS KFFREYEGKS 
    FTYAAFHAHK KYGVCLIGLK REENKSILLN PGPRHILAAS DTCFYINITK EENSAFIFKQ 
    EEKQKRRGLA GQALYEGPSR LPVHSIIASM GTVAMDLQNT DCRPSQGGSG GGGGKLTLPT 
    ENGSGSRRPS IAPVLELADS SALLPCDLLS DQSEDEVTPS DDEGLSVVEY VKGYPPNSPY 
    IGSSPTLCHL LPVKAPFCCL RLDKGCKHNS YEDAKAYGFK NKLIIVSAET AGNGLYNFIV 
    PLRAYYRSRR ELNPIVLLLD NKPDHHFLEA ICCFPMVYYM EGSVDNLDSL LQCGIIYADN 
    LVVVDKESTM SAEEDYMADA KTIVNVQTMF RLFPSLSITT ELTHPSNMRF MQFRAKDSYS 
    LALSKLEKQE RENGSNLAFM FRLPFAAGRV FSISMLDTLL YQSFVKDYMI TITRLLLGLD 
    TTPGSGYLCA MKVTEDDLWI RTYGRLFQKL CSSSAEIPIG IYRTECHVFS SEPHDLRAQS 
    QISVNMEDCE DTREAKGPWG TRAASGGGST HGRHGGSADP VEHPLLRRKS LQWARKLSRK 
    SSKQAGKAPM TTDWITQQRL SLYRRSERQE LSELVKNRMK HLGLPTTGYE DVANLTASDV 
    MNRVNLGYLQ DEMNDHHQNT LSYVLINPPP DTRLEPNDIV YLIRSDPLAH VTSSSQSRKS 
    SCSNKLSSCN PETRDETQL

Genular Protein ID: 3876400571

Symbol: D3ZNI9_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 1184
  • Mass: 134695
  • Checksum: 9A8088F4F3470B1E
  • Sequence:
  • MNDLDTEVLP LPPRYRFRDL LLGDQTFPND DRVQVEFYVN ENTFKERLKL FFIKNQRSSL 
    RIRLFNFSLK LLTCLLYIVR VLLDNPDQGI GCWGCTKYNY TFNGSSSEFH WAPILWVERK 
    MALWVIQVIV ATISFLETML LIYLSYKGNI WEQIFHVSFV LEMINTLPFI ITVFWPPLRN 
    LFIPVFLNCW LAKHALENMI NDFHRAILRT QSAMFNQVLI LFCTLLCLVF TGTCGIQHLE 
    RAGGNLNLLT SFYFCIVTFS TVGFGDVTPK IWPSQLLVVI LICVTLVVLP LQFEELVYLW 
    MERQKSGGNY SRHRARTEKH VVLCVSSLKI DLLMDFLNEF YAHPRLQDYY VVILCPSEMD 
    VQVRRVLQIP LWSQRVIYLQ GSALKDQDLM RAKMDNGEAC FILSSRNEVD RTAADHQTIL 
    RAWAVKDFAP NCPLYVQILK PENKFHVKFA DHVVCEEECK YAMLALNCIC PATSTLITLL 
    VHTSRGQEGQ ESPEQWQRMY GRCSGNEVYH IRMGDSKFFR EYEGKSFTYA AFHAHKKYGV 
    CLIGLKREEN KSILLNPGPR HILAASDTCF YINITKEENS AFIFKQEEKQ KRRGLAGQAL 
    YEGPSRLPVH SIIASMGTVA MDLQNTDCRP SQGGSGGGGG KLTLPTENGS GSRRPSIAPV 
    LELADSSALL PCDLLSDQSE DEVTPSDDEG LSVVEYVKGY PPNSPYIGSS PTLCHLLPVK 
    APFCCLRLDK GCKHNSYEDA KAYGFKNKLI IVSAETAGNG LYNFIVPLRA YYRSRRELNP 
    IVLLLDNKPD HHFLEAICCF PMVYYMEGSV DNLDSLLQCG IIYADNLVVV DKESTMSAEE 
    DYMADAKTIV NVQTMFRLFP SLSITTELTH PSNMRFMQFR AKDSYSLALS KLEKQERENG 
    SNLAFMFRLP FAAGRVFSIS MLDTLLYQSF VKDYMITITR LLLGLDTTPG SGYLCAMKVT 
    EDDLWIRTYG RLFQKLCSSS AEIPIGIYRT ECHVFSSEPH DLRAQSQISV NMEDCEDTRE 
    AKGPWGTRAA SGGGSTHGRH GGSADPVEHP LLRRKSLQWA RKLSRKSSKQ AGKAPMTTDW 
    ITQQRLSLYR RSERQELSEL VKNRMKHLGL PTTGYDEMND HHQNTLSYVL INPPPDTRLE 
    PNDIVYLIRS DPLAHVTSSS QSRKSSCSNK LSSCNPETRD ETQL

Genular Protein ID: 3456843568

Symbol: F1LSG1_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 1239
  • Mass: 139788
  • Checksum: 6050F7C860580089
  • Sequence:
  • MARAKLPRSP SEGKAGPGDT PAGSAAPEEP HGLSPLLPTR GGGSVGSDVG QRLHVEDFSL 
    DSSLSQVQVE FYVNENTFKE RLKLFFIKNQ RSSLRIRLFN FSLKLLTCLL YIVRVLLDNP 
    DQGIGCWGCT KYNYTFNGSS SEFHWAPILW VERKMALWVI QVIVATISFL ETMLLIYLSY 
    KGNIWEQIFH VSFVLEMINT LPFIITVFWP PLRNLFIPVF LNCWLAKHAL ENMINDFHRA 
    ILRTQSAMFN QVLILFCTLL CLVFTGTCGI QHLERAGGNL NLLTSFYFCI VTFSTVGFGD 
    VTPKIWPSQL LVVILICVTL VVLPLQFEEL VYLWMERQKS GGNYSRHRAR TEKHVVLCVS 
    SLKIDLLMDF LNEFYAHPRL QDYYVVILCP SEMDVQVRRV LQIPLWSQRV IYLQGSALKD 
    QDLMRAKMDN GEACFILSSR NEVDRTAADH QTILRAWAVK DFAPNCPLYV QILKPENKFH 
    VKFADHVVCE EECKYAMLAL NCICPATSTL ITLLVHTSRG QEGQESPEQW QRMYGRCSGN 
    EVYHIRMGDS KFFREYEGKS FTYAAFHAHK KYGVCLIGLK REENKSILLN PGPRHILAAS 
    DTCFYINITK EENSAFIFKQ EEKQKRRGLA GQALYEGPSR LPVHSIIASM GTVAMDLQNT 
    DCRPSQGGSG GGGGKLTLPT ENGSGSRRPS IAPVLELADS SALLPCDLLS DQSEDEVTPS 
    DDEGLSVVEY VKGYPPNSPY IGSSPTLCHL LPVKAPFCCL RLDKGCKHNS YEDAKAYGFK 
    NKLIIVSAET AGNGLYNFIV PLRAYYRSRR ELNPIVLLLD NKPDHHFLEA ICCFPMVYYM 
    EGSVDNLDSL LQCGIIYADN LVVVDKESTM SAEEDYMADA KTIVNVQTMF RLFPSLSITT 
    ELTHPSNMRF MQFRAKDSYS LALSKLEKQE RENGSNLAFM FRLPFAAGRV FSISMLDTLL 
    YQSFVKDYMI TITRLLLGLD TTPGSGYLCA MKVTEDDLWI RTYGRLFQKL CSSSAEIPIG 
    IYRTECHVFS SEPHDLRAQS QISVNMEDCE DTREAKGPWG TRAASGGGST HGRHGGSADP 
    VEHPLLRRKS LQWARKLSRK SSKQAGKAPM TTDWITQQRL SLYRRSERQE LSELVKNRMK 
    HLGLPTTGYE DVANLTASDV MNRVNLGYLQ DEMNDHHQNT LSYVLINPPP DTRLEPNDIV 
    YLIRSDPLAH VTSSSQSRKS SCSNKLSSCN PETRDETQL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.