Details for: Cttn

Gene ID: 60465

Symbol: Cttn

Ensembl ID: ENSRNOG00000050994

Description: cortactin

Associated with

Other Information

Genular Protein ID: 2678669376

Symbol: SRC8_RAT

Name: Src substrate cortactin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12612086

Title: Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis.

PubMed ID: 12612086

DOI: 10.1128/mcb.23.6.2162-2170.2003

PubMed ID: 12151401

Title: Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin.

PubMed ID: 12151401

DOI: 10.1074/jbc.m205005200

PubMed ID: 17959782

Title: An essential role for cortactin in the modulation of the potassium channel Kv1.2.

PubMed ID: 17959782

DOI: 10.1073/pnas.0703865104

PubMed ID: 18768925

Title: Distinct phospho-forms of cortactin differentially regulate actin polymerization and focal adhesions.

PubMed ID: 18768925

DOI: 10.1152/ajpcell.00238.2008

PubMed ID: 19995918

Title: SRC-mediated phosphorylation of dynamin and cortactin regulates the 'constitutive' endocytosis of transferrin.

PubMed ID: 19995918

DOI: 10.1128/mcb.00330-09

PubMed ID: 21210813

Title: Growth cone morphology and spreading are regulated by a dynamin-cortactin complex at point contacts in hippocampal neurons.

PubMed ID: 21210813

DOI: 10.1111/j.1471-4159.2011.07169.x

PubMed ID: 23144454

Title: Cortactin controls surface expression of the voltage-gated potassium channel K(V)10.1.

PubMed ID: 23144454

DOI: 10.1074/jbc.m112.372540

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 22952866

Title: Cortactin as a target for FAK in the regulation of focal adhesion dynamics.

PubMed ID: 22952866

DOI: 10.1371/journal.pone.0044041

Sequence Information:

  • Length: 509
  • Mass: 56942
  • Checksum: 059CDB52681E2592
  • Sequence:
  • MWKASAGHAV SITQDDGGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE 
    NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 
    FGGKFGVQMD RVDQSAVGFE YQGKTEKHAS QKDYSSGFGG KYGVQADRVD KSAVGFDYQG 
    KTEKHESQKD YSKGFGGKYG IDKDKVDKSA VGFEYQGKTE KHESQKDYVK GFGGKFGVQT 
    DRQDKCALGW DHQEKLQLHE SQKDYAKGFG GKYGVQKDRM DKNASTFEEV VQVPSAYQKT 
    VPIEAVTSKT SNIRANFENL AKEREQEDRR KAEAERAQRM AQERQEQEEA RRKLEEQARA 
    KKQTPPASPS PQPAEDRPPS SPIYEDAAPL KAEPSYGSSE PEPEYSTEAA GLPEASNQQG 
    LAYTSEPVYE TTEVPGHYQA EDDTYDGYES DLGITAIALY DYQAAGDDEI SFDPDDVITN 
    IEMIDDGWWR GVCKGRYGLF PANYVELRQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.