Details for: BCL7A
Gene ID: 605
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: BCL7A
Ensembl ID: ENSG00000110987
Description: BAF chromatin remodeling complex subunit BCL7A
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 13.09rCSI 15.93%PRS 77.8
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CSI 9.66rCSI 7.18%PRS 83.1
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CSI 8.42rCSI 8.1%PRS 88.37
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CSI 7.94rCSI 22.68%PRS 79.57
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CSI 7.46rCSI 15.41%PRS 70.13
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CSI 5.87rCSI 7.37%PRS 80.63
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CSI 5.34rCSI 6.16%PRS 63.01
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CSI 4.66rCSI 9.91%PRS 66.9
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CSI 4.52rCSI 11.33%PRS 89.07
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CSI 4.22rCSI 13.6%PRS 68.4
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CSI 4.06rCSI 3.53%PRS 81.17
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CSI 3.92rCSI 14.91%PRS 61.14
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CSI 3.82rCSI 6.74%PRS 50.95
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CSI 3.49rCSI 2.93%PRS 74.08
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CSI 3.32rCSI 3.42%PRS 85.12
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CSI 3.23rCSI 4.32%PRS 78.68
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CSI 3.23rCSI 2.83%PRS 79.19
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CSI 3.22rCSI 3.33%PRS 76.17
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CSI 3.15rCSI 6.32%PRS 59.94
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CSI 3.09rCSI 2.65%PRS 78.02
-
CSI 2.91rCSI 8.69%PRS 84.14
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CSI 2.86rCSI 3.06%PRS 71.13
-
CSI 2.86rCSI 3.82%PRS 83.38
-
CSI 2.84rCSI 5.83%PRS 59.38
-
CSI 2.82rCSI 2.44%PRS 75.43
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CSI 2.78rCSI 2.3%PRS 73.12
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CSI 2.72rCSI 16.97%PRS 62.06
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CSI 2.71rCSI 4.16%PRS 63.14
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CSI 2.7rCSI 5.97%PRS 56.53
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CSI 2.69rCSI 6.45%PRS 78.1
-
CSI 2.68rCSI 2.67%PRS 64.14
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CSI 2.67rCSI 3.43%PRS 74.94
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CSI 2.66rCSI 4.32%PRS 66.29
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CSI 2.64rCSI 4.75%PRS 63.72
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CSI 2.64rCSI 3.93%PRS 71.21
-
CSI 2.62rCSI 1.95%PRS 85.42
-
CSI 2.6rCSI 2.56%PRS 73.25
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CSI 2.52rCSI 3.57%PRS 66.89
-
CSI 2.48rCSI 1.73%PRS 73.61
-
CSI 2.4rCSI 2.11%PRS 76.09
-
CSI 2.38rCSI 13.45%PRS 56.01
-
CSI 2.34rCSI 3.2%PRS 74.98
-
CSI 2.32rCSI 2.1%PRS 68.01
-
CSI 2.31rCSI 7.56%PRS 90.62
-
CSI 2.28rCSI 3.12%PRS 71.63
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CSI 2.27rCSI 3.11%PRS 76.19
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CSI 2.25rCSI 1.78%PRS 57.9
-
CSI 2.2rCSI 3.24%PRS 63.65
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CSI 2.18rCSI 1.81%PRS 70.71
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CSI 2.18rCSI 6.44%PRS 72.59
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CSI 2.11rCSI 3.21%PRS 66.97
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CSI 2.1rCSI 2.41%PRS 85.5
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CSI 2.09rCSI 2.02%PRS 62.4
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CSI 2.07rCSI 3.3%PRS 62.34
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CSI 2.06rCSI 2.46%PRS 51.72
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CSI 2rCSI 3.06%PRS 71.47
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CSI 1.99rCSI 4.92%PRS 69.48
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CSI 1.92rCSI 1.96%PRS 81.94
-
CSI 1.91rCSI 2.31%PRS 79.78
-
CSI 1.89rCSI 2.62%PRS 69.03
-
CSI 1.87rCSI 3.36%PRS 70.23
-
CSI 1.87rCSI 5.4%PRS 79.92
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CSI 1.85rCSI 2.31%PRS 49.96
-
CSI 1.85rCSI 1.23%PRS 73.5
-
CSI 1.85rCSI 7.55%PRS 63.55
-
CSI 1.85rCSI 4.7%PRS 60.29
-
CSI 1.8rCSI 2.31%PRS 67.12
-
CSI 1.78rCSI 7.82%PRS 59.78
-
CSI 1.77rCSI 2.05%PRS 61.67
-
CSI 1.76rCSI 1.43%PRS 72.59
-
CSI 1.75rCSI 1.54%PRS 58.7
-
CSI 1.71rCSI 5.74%PRS 55.12
-
CSI 1.71rCSI 1.39%PRS 70.82
-
CSI 1.71rCSI 3.95%PRS 58.79
-
CSI 1.57rCSI 2.14%PRS 61.97
-
CSI 1.55rCSI 3.48%PRS 52.47
-
CSI 1.53rCSI 2.19%PRS 72.44
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CSI 1.53rCSI 1.47%PRS 70.31
-
CSI 1.52rCSI 3.72%PRS 63.7
-
CSI 1.48rCSI 1.9%PRS 53.26
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CSI 1.47rCSI 3.23%PRS 81.43
-
CSI 1.45rCSI 4.21%PRS 59.82
-
CSI 1.44rCSI 3.71%PRS 65.61
-
CSI 1.38rCSI 4.47%PRS 69.89
-
CSI 1.35rCSI 3.22%PRS 71.15
-
CSI 1.35rCSI 1.95%PRS 85.46
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CSI 1.26rCSI 2.03%PRS 53.76
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CSI 1.25rCSI 4.71%PRS 54.51
-
CSI 1.25rCSI 1.79%PRS 60.15
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CSI 1.15rCSI 2.16%PRS 58.4
-
CSI 1.15rCSI 3.07%PRS 61.62
-
CSI 1.14rCSI 3.56%PRS 53.68
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CSI 1.13rCSI 1.9%PRS 51.85
-
CSI 1.1rCSI 2.64%PRS 86.29
-
CSI 1.04rCSI 1.39%PRS 88.24
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CSI 0.97rCSI 1.56%PRS 60.03
-
CSI 0.92rCSI 1.79%PRS 74.09
-
CSI 0.87rCSI 2.12%PRS 50.28
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CSI 0.87rCSI 2.79%PRS 74.09
-
CSI 0.67rCSI 2.6%PRS 88.64
-
CSI 0.2rCSI 4.9%PRS 83.9%
-
CSI 0.2rCSI 5.3%PRS 50.9%
-
CSI 0.2rCSI 5.3%PRS 51.5%
-
CSI 0.4rCSI 2.2%PRS 78.3%
-
CSI 0.4rCSI 6.1%PRS 81.2%
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CSI 0.4rCSI 2.5%PRS 53.0%
-
CSI 0.4rCSI 3.4%PRS 78.8%
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CSI 0.5rCSI 2.5%PRS 89.1%
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CSI 0.5rCSI 1.7%PRS 50.1%
-
CSI 0.5rCSI 1.3%PRS 79.7%
-
CSI 0.6rCSI 1.7%PRS 56.2%
-
CSI 0.6rCSI 2.2%PRS 52.4%
-
CSI 0.6rCSI 4.3%PRS 57.4%
-
CSI 0.7rCSI 2.6%PRS 88.6%
-
CSI 0.9rCSI 2.8%PRS 74.1%
-
CSI 0.9rCSI 2.1%PRS 50.3%
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CSI 0.9rCSI 1.8%PRS 74.1%
-
CSI 1.0rCSI 1.6%PRS 60.0%
-
CSI 1.0rCSI 1.4%PRS 88.2%
-
CSI 1.1rCSI 2.6%PRS 86.3%
-
CSI 1.1rCSI 1.9%PRS 51.9%
-
CSI 1.1rCSI 3.6%PRS 53.7%
-
CSI 1.2rCSI 3.1%PRS 61.6%
-
CSI 1.2rCSI 2.2%PRS 58.4%
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CSI 1.3rCSI 1.8%PRS 60.2%
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CSI 1.3rCSI 4.7%PRS 54.5%
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CSI 1.3rCSI 2.0%PRS 53.8%
-
CSI 1.4rCSI 2.0%PRS 85.5%
-
CSI 1.4rCSI 3.2%PRS 71.2%
-
CSI 1.4rCSI 4.5%PRS 69.9%
-
CSI 1.4rCSI 3.7%PRS 65.6%
-
CSI 1.5rCSI 4.2%PRS 59.8%
-
CSI 1.5rCSI 3.2%PRS 81.4%
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CSI 1.5rCSI 1.9%PRS 53.3%
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CSI 1.5rCSI 3.7%PRS 63.7%
-
CSI 1.5rCSI 1.5%PRS 70.3%
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CSI 1.5rCSI 2.2%PRS 72.4%
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CSI 1.6rCSI 3.5%PRS 52.5%
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CSI 1.6rCSI 2.1%PRS 62.0%
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CSI 1.7rCSI 4.0%PRS 58.8%
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CSI 1.7rCSI 1.4%PRS 70.8%
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CSI 1.7rCSI 5.7%PRS 55.1%
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CSI 1.8rCSI 1.5%PRS 58.7%
-
CSI 1.8rCSI 1.4%PRS 72.6%
-
CSI 1.8rCSI 2.1%PRS 61.7%
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CSI 1.8rCSI 7.8%PRS 59.8%
-
CSI 1.8rCSI 2.3%PRS 67.1%
-
CSI 1.9rCSI 4.7%PRS 60.3%
-
CSI 1.9rCSI 7.6%PRS 63.6%
-
CSI 1.9rCSI 1.2%PRS 73.5%
-
CSI 1.9rCSI 2.3%PRS 50.0%
-
CSI 1.9rCSI 5.4%PRS 79.9%
-
CSI 1.9rCSI 3.4%PRS 70.2%
-
CSI 1.9rCSI 2.6%PRS 69.0%
-
CSI 1.9rCSI 2.3%PRS 79.8%
-
CSI 1.9rCSI 2.0%PRS 81.9%
-
CSI 2.0rCSI 4.9%PRS 69.5%
-
CSI 2.0rCSI 3.1%PRS 71.5%
-
CSI 2.1rCSI 2.5%PRS 51.7%
-
CSI 2.1rCSI 3.3%PRS 62.3%
-
CSI 2.1rCSI 2.0%PRS 62.4%
-
CSI 2.1rCSI 2.4%PRS 85.5%
-
CSI 2.1rCSI 3.2%PRS 67.0%
-
CSI 2.2rCSI 6.4%PRS 72.6%
-
CSI 2.2rCSI 1.8%PRS 70.7%
-
CSI 2.2rCSI 3.2%PRS 63.7%
-
CSI 2.3rCSI 1.8%PRS 57.9%
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CSI 2.3rCSI 3.1%PRS 76.2%
-
CSI 2.3rCSI 3.1%PRS 71.6%
-
CSI 2.3rCSI 7.6%PRS 90.6%
-
CSI 2.3rCSI 2.1%PRS 68.0%
-
CSI 2.3rCSI 3.2%PRS 75.0%
-
CSI 2.4rCSI 13.5%PRS 56.0%
-
CSI 2.4rCSI 2.1%PRS 76.1%
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CSI 2.5rCSI 1.7%PRS 73.6%
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CSI 2.5rCSI 3.6%PRS 66.9%
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CSI 2.6rCSI 2.6%PRS 73.3%
-
CSI 2.6rCSI 2.0%PRS 85.4%
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CSI 2.6rCSI 3.9%PRS 71.2%
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CSI 2.6rCSI 4.8%PRS 63.7%
-
CSI 2.7rCSI 4.3%PRS 66.3%
-
CSI 2.7rCSI 3.4%PRS 74.9%
-
CSI 2.7rCSI 2.7%PRS 64.1%
-
CSI 2.7rCSI 6.5%PRS 78.1%
-
CSI 2.7rCSI 6.0%PRS 56.5%
-
CSI 2.7rCSI 4.2%PRS 63.1%
-
CSI 2.7rCSI 17.0%PRS 62.1%
-
CSI 2.8rCSI 2.3%PRS 73.1%
-
CSI 2.8rCSI 2.4%PRS 75.4%
-
CSI 2.8rCSI 5.8%PRS 59.4%
-
CSI 2.9rCSI 3.8%PRS 83.4%
-
CSI 2.9rCSI 3.1%PRS 71.1%
-
CSI 2.9rCSI 8.7%PRS 84.1%
-
CSI 3.1rCSI 2.7%PRS 78.0%
-
CSI 3.2rCSI 6.3%PRS 59.9%
-
CSI 3.2rCSI 3.3%PRS 76.2%
-
CSI 3.2rCSI 2.8%PRS 79.2%
-
CSI 3.2rCSI 4.3%PRS 78.7%
-
CSI 3.3rCSI 3.4%PRS 85.1%
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CSI 3.5rCSI 2.9%PRS 74.1%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1312696442
Symbol: BCL7A_HUMAN
Name: B-cell CLL/lymphoma 7 protein family member A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8605326
Title: Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon.
PubMed ID: 8605326
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
Sequence Information:
- Length: 210
- Mass: 22810
- Checksum: 4AB4AC3B309ADDB8
- Sequence:
MSGRSVRAET RSRAKDDIKR VMAAIEKVRK WEKKWVTVGD TSLRIYKWVP VTEPKVDDKN KNKKKGKDEK CGSEVTTPEN SSSPGMMDMH DDNSNQSSIA DASPIKQENS SNSSPAPEPN SAVPSDGTEA KVDEAQADGK EHPGAEDASD EQNSQSSMEH SMNSSEKVDR QPSGDSGLAA ETSAISQDLE GVPPSKKMKL EASQQNSEEM