Details for: Syt11

Gene ID: 60568

Symbol: Syt11

Ensembl ID: ENSRNOG00000020279

Description: synaptotagmin 11

Associated with

Other Information

Genular Protein ID: 2965411254

Symbol: SYT11_RAT

Name: Synaptotagmin XI

UniProtKB Accession Codes:

O08835 Q925B6

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 CDD 2 CTD 1 ChEBI 4 EMBL 2 GO 66 Gene3D 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 2 Reactome 2 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9162066

Title: The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding.

PubMed ID: 9162066

DOI: 10.1074/jbc.272.22.14314

PubMed ID: 24882364

Title: Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells.

PubMed ID: 24882364

DOI: 10.1016/j.febslet.2014.05.031

PubMed ID: 26589353

Title: Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis.

PubMed ID: 26589353

DOI: 10.15252/embr.201540689

PubMed ID: 29311685

Title: Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology.

PubMed ID: 29311685

DOI: 10.1038/s41467-017-02593-y

PubMed ID: 30021165

Title: Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-alpha/TANC2 Recruits DCVs to Postsynaptic Sites.

PubMed ID: 30021165

DOI: 10.1016/j.celrep.2018.06.071

Sequence Information:

  • Length: 430
  • Mass: 48268
  • Checksum: FEEB06702BAC2AFB
  • Sequence:
    • MAEITNIRPS FDVSPVAAGL IGASVLVVCV SVTVFVWTCC HQQAEKKHKT PPYKFIHMLK 
GISIYPETLS NKKKIIKVRR DKDGSHRESG RGNLLVNAES GLLSHDRDPR GPSPASCIDQ 
LPIKRDYGEE LRSPMTSLTP GESKPTSPSS PEEDVMLGSL TFSVDYNFPK KALVVTIQEA 
HGLPVMDGQT QGSDPYIKMT ILPDKRHRVK TRVLRKTLDP VFDETFTFYG IPYSQLQDLV 
LHFLVLSFDR FSRDDVIGEV MVPLAGVDPS TGKVQLTRDI IKRNIQKCIS RGELQVSLSY 
QPVAQRMTVV VLKARHLPKM DITGLSGNPY VKVNVYYGRK RIAKKKTHVK KCTLNPIFNE 
SFIYDIPTDL LPDISIEFLV IDFDRTTKNE VVGRLILGAH SVTTSGAEHW REVCESPRKP 
VAKWHSLSEY

Genular Protein ID: 1958835363

Symbol: Q505J5_RAT

Name: N/A

UniProtKB Accession Codes:

Q505J5

Database IDs:

ARBA 2 CDD 2 CTD 1 EMBL 2 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 HOGENOM 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 2 Pfam 1 Proteomes 2 RGD 2 RefSeq 1 SAM 2 SMART 1 SUPFAM 1 TreeFam 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 429
  • Mass: 48212
  • Checksum: 6FF1C83EA81AD0C6
  • Sequence:
    • MAEITNIRPS FDVSPVAAGL IGASVLVVCV SVTVFVWTCC HQQAEKKHKT PPYKFIHMLK 
GISIYPETLS NKKKIIKVRR DKDGSHRESG RGNLLVNAES GLLSHDRDPR GPSPASCIDQ 
LPIKRDYGEE LRSPMTSLTP GESKPTSPSS PEEDVMLGSL TFSVDYNFPK KALVVTIQEA 
HGLPVMDGQT QGSDPYIKMT ILPDKRHRVK TRVLRKTLDP VFDETFTFYG IPYSQLQDLV 
LHFLVLSFDR FSRDDVIGEV MVPLAGVDPS TGKVQLTRDI IKRNIQKCIS RGELQVSLSY 
QPVAQRMTVV VLKARHLPKM DITGLSDPYV KVNVYYGRKR IAKKKTHVKK CTLNPIFNES 
FIYDIPTDLL PDISIEFLVI DFDRTTKNEV VGRLILGAHS VTTSGAEHWR EVCESPRKPV 
AKWHSLSEY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.