Actn4 | ENSMUSG00000054808 | NCBI 60595

Details for: Actn4

Gene ID: 60595

Symbol: Actn4

Ensembl ID: ENSMUSG00000054808

Description: actinin alpha 4

Associated with

Hemostasis
(R-MMU-109582)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Actin binding
(GO:0003779)
Actin cytoskeleton
(GO:0015629)
Actin cytoskeleton organization
(GO:0030036)
Actin filament binding
(GO:0051015)
Actin filament bundle assembly
(GO:0051017)
Anchoring junction
(GO:0070161)
Bicellular tight junction assembly
(GO:0070830)
Calcium ion binding
(GO:0005509)
Cell-cell junction
(GO:0005911)
Cell junction
(GO:0030054)
Cell projection
(GO:0042995)
Chromatin dna binding
(GO:0031490)
Cortical actin cytoskeleton
(GO:0030864)
Cortical cytoskeleton
(GO:0030863)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Focal adhesion
(GO:0005925)
Gene expression
(GO:0010467)
Glomerulus development
(GO:0032835)
Metal ion binding
(GO:0046872)
Muscle cell development
(GO:0055001)
Negative regulation of substrate adhesion-dependent cell spreading
(GO:1900025)
Neuron projection
(GO:0043005)
Nuclear receptor binding
(GO:0016922)
Nuclear receptor coactivator activity
(GO:0030374)
Nuclear retinoic acid receptor binding
(GO:0042974)
Nucleoside binding
(GO:0001882)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Peroxisome proliferator activated receptor signaling pathway
(GO:0035357)
Plasma membrane
(GO:0005886)
Podocyte cell migration
(GO:0090521)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of non-canonical nf-kappab signal transduction
(GO:1901224)
Positive regulation of pinocytosis
(GO:0048549)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein localization to bicellular tight junction
(GO:1902396)
Protein transport
(GO:0015031)
Pseudopodium
(GO:0031143)
Regulation of apoptotic process
(GO:0042981)
Retinoic acid receptor signaling pathway
(GO:0048384)
Ribonucleoprotein complex
(GO:1990904)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Stress fiber
(GO:0001725)
Structural constituent of cytoskeleton
(GO:0005200)
Transcription coactivator activity
(GO:0003713)
Transmembrane transporter binding
(GO:0044325)
Tumor necrosis factor-mediated signaling pathway
(GO:0033209)
Ubiquitin protein ligase binding
(GO:0031625)
Vesicle transport along actin filament
(GO:0030050)
Z disc
(GO:0030018)

Other Information

Proteins

ACTN4_MOUSE

Genular Protein ID: 1842136240

Symbol: ACTN4_MOUSE

Name: N/A

UniProtKB Accession Codes:

P57780

Database IDs:

Citations:

PubMed ID: 10964513

Title: Gene structure, chromosomal localization and expression pattern of Capn12, a new member of the calpain large subunit gene family.

PubMed ID: 10964513

DOI: 10.1006/geno.2000.6289

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18332111

Title: Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions.

PubMed ID: 18332111

DOI: 10.1128/mcb.00144-08

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 33228246

Title: ACTN4 Mediates SEPT14 Mutation-Induced Sperm Head Defects.

PubMed ID: 33228246

DOI: 10.3390/biomedicines8110518

Sequence Information:

Length: 912
Mass: 104977
Checksum: 07AA9C92AC228B5A
Sequence:

MVDYHAANQA YQYGPNSGGG NGAGGGGSMG DYMAQEDDWD RDLLLDPAWE KQQRKTFTAW 
CNSHLRKAGT QIENIDEDFR DGLKLMLLLE VISGERLPKP ERGKMRVHKI NNVNKALDFI 
ASKGVKLVSI GAEEIVDGNA KMTLGMIWTI ILRFAIQDIS VEETSAKEGL LLWCQRKTAP 
YKNVNVQNFH ISWKDGLAFN ALIHRHRPEL IEYDKLRKDD PVTNLNNAFE VAEKYLDIPK 
MLDAEDIVNT ARPDEKAIMT YVSSFYHAFS GAQKAETAAN RICKVLAVNQ ENEHLMEDYE 
RLASDLLEWI RRTIPWLEDR VPQKTIQEMQ QKLEDFRDYR RVHKPPKVQE KCQLEINFNT 
LQTKLRLSNR PAFMPSEGRM VSDINNGWQH LEQAEKGYEE WLLNEIRRLE RLDHLAEKFR 
QKASIHEAWT DGKEAMLKQR DYETATLSDI KALIRKHEAF ESDLAAHQDR VEQIAAIAQE 
LNELDYYDSH NVNTRCQKIC DQWDNLGSLT HSRREALEKT EKQLETIDQL HLEYAKRAAP 
FNNWMESAME DLQDMFIVHT IEEIEGLISA HDQFKSTLPD ADREREAILA IHKEAQRIAE 
SNHIKLSGSN PYTTVTPQII NSKWEKVQQL VPKRDHALLE EQSKQQSNEH LRRQFASQAN 
MVGPWIQTKM EEIGRISIEM NGTLEDQLSH LKQYERSIVD YKPSLDLLEQ QHQLIQEALI 
FDNKHTNYTM EHIRVGWEQL LTTIARTINE VENQILTRDA KGISQEQMQE FRASFNHFDK 
DHGGALGPEE FKACLISLGY DVENDRQGDA EFNRIMSVVD PNHSGLVTFQ AFIDFMSRET 
TDTDTADQVI ASFKVLAGDK NFITAEELRR ELPPDQAEYC IARMAPYQGP DAAPGALDYK 
SFSTALYGES DL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Actn4

Associated with

Other Information

Gene structure, chromosomal localization and expression pattern of Capn12, a new member of the calpain large subunit gene family. PubMed ID: 10964513

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions. PubMed ID: 18332111

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337