Cxcr4 | ENSRNOG00000003866 | NCBI 60628

Details for: Cxcr4

Gene ID: 60628

Symbol: Cxcr4

Ensembl ID: ENSRNOG00000003866

Description: C-X-C motif chemokine receptor 4

Associated with

Chemokine receptors bind chemokines
(R-RNO-380108)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Actin binding
(GO:0003779)
Aorta development
(GO:0035904)
Blood vessel endothelial cell migration
(GO:0043534)
Brain development
(GO:0007420)
Branching involved in blood vessel morphogenesis
(GO:0001569)
C-c chemokine binding
(GO:0019957)
C-c chemokine receptor activity
(GO:0016493)
C-x-c chemokine receptor activity
(GO:0016494)
C-x-c motif chemokine 12 receptor activity
(GO:0038147)
Calcium-mediated signaling
(GO:0019722)
Cardiac muscle contraction
(GO:0060048)
Cell-cell junction
(GO:0005911)
Cell chemotaxis
(GO:0060326)
Cell leading edge
(GO:0031252)
Cell migration
(GO:0016477)
Cell surface
(GO:0009986)
Cellular response to cytokine stimulus
(GO:0071345)
Cellular response to organonitrogen compound
(GO:0071417)
Cellular response to xenobiotic stimulus
(GO:0071466)
Cxcl12-activated cxcr4 signaling pathway
(GO:0038160)
Cytoplasmic vesicle
(GO:0031410)
Detection of mechanical stimulus involved in sensory perception of pain
(GO:0050966)
Detection of temperature stimulus involved in sensory perception of pain
(GO:0050965)
Early endosome
(GO:0005769)
Endosome
(GO:0005768)
Endothelial cell differentiation
(GO:0045446)
Endothelial tube morphogenesis
(GO:0061154)
Epithelial cell development
(GO:0002064)
External side of plasma membrane
(GO:0009897)
Generation of neurons
(GO:0048699)
Germ cell development
(GO:0007281)
Germ cell migration
(GO:0008354)
G protein-coupled receptor signaling pathway
(GO:0007186)
Growth cone
(GO:0030426)
Hematopoietic stem cell migration
(GO:0035701)
Immune response
(GO:0006955)
Kidney development
(GO:0001822)
Late endosome
(GO:0005770)
Lysosome
(GO:0005764)
Motor neuron axon guidance
(GO:0008045)
Myelin maintenance
(GO:0043217)
Myosin light chain binding
(GO:0032027)
Neural precursor cell proliferation
(GO:0061351)
Neurogenesis
(GO:0022008)
Neuron migration
(GO:0001764)
Neuron recognition
(GO:0008038)
Osteoclast differentiation
(GO:0030316)
Plasma membrane
(GO:0005886)
Positive regulation of calcium ion import
(GO:0090280)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of chemotaxis
(GO:0050921)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of dendrite extension
(GO:1903861)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of macrophage migration inhibitory factor signaling pathway
(GO:2000448)
Positive regulation of mesenchymal stem cell migration
(GO:1905322)
Positive regulation of neurogenesis
(GO:0050769)
Positive regulation of oligodendrocyte differentiation
(GO:0048714)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of vascular wound healing
(GO:0035470)
Positive regulation of vasculature development
(GO:1904018)
Protein-containing complex
(GO:0032991)
Regulation of calcium ion transport
(GO:0051924)
Regulation of cell adhesion
(GO:0030155)
Regulation of cell migration
(GO:0030334)
Regulation of chemotaxis
(GO:0050920)
Regulation of neuron migration
(GO:2001222)
Regulation of programmed cell death
(GO:0043067)
Regulation of viral process
(GO:0050792)
Response to activity
(GO:0014823)
Response to hypoxia
(GO:0001666)
Response to organic cyclic compound
(GO:0014070)
Response to tacrolimus
(GO:1901327)
Response to ultrasound
(GO:1990478)
Small molecule binding
(GO:0036094)
T cell proliferation
(GO:0042098)
Telencephalon cell migration
(GO:0022029)
Ubiquitin binding
(GO:0043130)
Ubiquitin protein ligase binding
(GO:0031625)
Ventricular septum development
(GO:0003281)

Other Information

Proteins

C-X-C chemokine receptor type 4

Genular Protein ID: 31035206

Symbol: CXCR4_RAT

Name: C-X-C chemokine receptor type 4

UniProtKB Accession Codes:

O08565 F1LPN8 Q8VD47

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 349
Mass: 39429
Checksum: 09D19860D3D2CB8A
Sequence:

MEIYTSDNYS EEVGSGDYDS NKEPCFRDEN ENFNRIFLPT IYFIIFLTGI VGNGLVILVM 
GYQKKLRSMT DKYRLHLSVA DLLFVITLPF WAVDAMADWY FGKFLCKAVH IIYTVNLYSS 
VLILAFISLD RYLAIVHATN SQRPRKLLAE KAVYVGVWIP ALLLTIPDII FADVSQGDGR 
YICDRLYPDS LWMVVFQFQH IMVGLILPGI VILSCYCIII SKLSHSKGHQ KRKALKTTVI 
LILAFFACWL PYYVGISIDS FILLEVIKQG CEFESVVHKW ISITEALAFF HCCLNPILYA 
FLGAKFKSSA QHALNSMSRG SSLKILSKGK RGGHSSVSTE SESSSFHSS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.