Details for: BCL9
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 143.1738
Cell Significance Index: -22.2700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 87.0514
Cell Significance Index: -22.0800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 51.2790
Cell Significance Index: -24.2100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 18.1393
Cell Significance Index: -22.3700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.1046
Cell Significance Index: -24.3900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.6816
Cell Significance Index: -22.4200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.3186
Cell Significance Index: 81.0500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 1.1702
Cell Significance Index: 28.0700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.1140
Cell Significance Index: 62.5100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.0509
Cell Significance Index: 23.0100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9995
Cell Significance Index: 902.4600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.8905
Cell Significance Index: 12.1500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6863
Cell Significance Index: 474.6600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6624
Cell Significance Index: 72.0500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6601
Cell Significance Index: 107.3700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.6483
Cell Significance Index: 130.0500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.5989
Cell Significance Index: 45.9600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5410
Cell Significance Index: 32.4800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4602
Cell Significance Index: 91.3200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4293
Cell Significance Index: 154.0000 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.3885
Cell Significance Index: 5.5300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3348
Cell Significance Index: 15.1800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3198
Cell Significance Index: 22.1200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.2739
Cell Significance Index: 18.4200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2558
Cell Significance Index: 7.3700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.2171
Cell Significance Index: 118.5600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2090
Cell Significance Index: 39.7800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2068
Cell Significance Index: 5.1700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1786
Cell Significance Index: 3.8700 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.1713
Cell Significance Index: 2.1300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1536
Cell Significance Index: 27.6900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1450
Cell Significance Index: 14.3400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.1284
Cell Significance Index: 3.3000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1148
Cell Significance Index: 15.7600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0816
Cell Significance Index: 10.4600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0791
Cell Significance Index: 34.9500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0700
Cell Significance Index: 4.4200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0542
Cell Significance Index: 1.9100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0414
Cell Significance Index: 0.7100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0407
Cell Significance Index: 76.6700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0352
Cell Significance Index: 1.6400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0282
Cell Significance Index: 51.9800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0188
Cell Significance Index: 28.8900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0173
Cell Significance Index: 11.0200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0121
Cell Significance Index: 5.5100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0029
Cell Significance Index: -2.1800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0068
Cell Significance Index: -4.2200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0068
Cell Significance Index: -0.1900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0086
Cell Significance Index: -1.2500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0091
Cell Significance Index: -12.3300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0165
Cell Significance Index: -2.8200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0190
Cell Significance Index: -13.9500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0207
Cell Significance Index: -2.5500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0216
Cell Significance Index: -12.1900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0274
Cell Significance Index: -20.7100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0517
Cell Significance Index: -5.9200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0534
Cell Significance Index: -11.2500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.0587
Cell Significance Index: -1.2600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0601
Cell Significance Index: -1.0100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0767
Cell Significance Index: -8.9400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0802
Cell Significance Index: -23.0800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0850
Cell Significance Index: -1.8100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0875
Cell Significance Index: -6.1900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1331
Cell Significance Index: -15.2000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1361
Cell Significance Index: -2.0100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1471
Cell Significance Index: -5.1100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1485
Cell Significance Index: -3.0800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1515
Cell Significance Index: -15.4800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1582
Cell Significance Index: -8.2200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1657
Cell Significance Index: -21.4100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1697
Cell Significance Index: -17.6700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1704
Cell Significance Index: -20.0900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1788
Cell Significance Index: -2.5600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1936
Cell Significance Index: -6.2000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2151
Cell Significance Index: -16.0300 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.2193
Cell Significance Index: -4.5900 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2393
Cell Significance Index: -4.6700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2503
Cell Significance Index: -19.8200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2646
Cell Significance Index: -7.5500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2695
Cell Significance Index: -14.1500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2802
Cell Significance Index: -5.5400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.2803
Cell Significance Index: -7.6300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2884
Cell Significance Index: -10.9200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2936
Cell Significance Index: -18.0000 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3080
Cell Significance Index: -8.1000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3120
Cell Significance Index: -8.3300 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.3128
Cell Significance Index: -6.2800 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.3192
Cell Significance Index: -4.8100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3230
Cell Significance Index: -16.8300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3256
Cell Significance Index: -21.0100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3500
Cell Significance Index: -15.4800 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.3559
Cell Significance Index: -3.0300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3581
Cell Significance Index: -16.8300 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.3667
Cell Significance Index: -6.3400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3752
Cell Significance Index: -11.9500 - Cell Name: peg cell (CL4033014)
Fold Change: -0.3909
Cell Significance Index: -9.0300 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.4081
Cell Significance Index: -4.2300 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: -0.4301
Cell Significance Index: -4.5700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.4322
Cell Significance Index: -14.1500 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.4991
Cell Significance Index: -6.4000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3916718572
Symbol: BCL9_HUMAN
Name: B-cell CLL/lymphoma 9 protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9490669
Title: Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21.
PubMed ID: 9490669
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 11955446
Title: Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.
PubMed ID: 11955446
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 17052462
Title: Crystal structure of a beta-catenin/BCL9/Tcf4 complex.
PubMed ID: 17052462
PubMed ID: 18498752
Title: Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.
PubMed ID: 18498752
Sequence Information:
- Length: 1426
- Mass: 149290
- Checksum: 51EF3D0DCA2103CB
- Sequence:
MHSSNPKVRS SPSGNTQSSP KSKQEVMVRP PTVMSPSGNP QLDSKFSNQG KQGGSASQSQ PSPCDSKSGG HTPKALPGPG GSMGLKNGAG NGAKGKGKRE RSISADSFDQ RDPGTPNDDS DIKECNSADH IKSQDSQHTP HSMTPSNATA PRSSTPSHGQ TTATEPTPAQ KTPAKVVYVF STEMANKAAE AVLKGQVETI VSFHIQNISN NKTERSTAPL NTQISALRND PKPLPQQPPA PANQDQNSSQ NTRLQPTPPI PAPAPKPAAP PRPLDRESPG VENKLIPSVG SPASSTPLPP DGTGPNSTPN NRAVTPVSQG SNSSSADPKA PPPPPVSSGE PPTLGENPDG LSQEQLEHRE RSLQTLRDIQ RMLFPDEKEF TGAQSGGPQQ NPGVLDGPQK KPEGPIQAMM AQSQSLGKGP GPRTDVGAPF GPQGHRDVPF SPDEMVPPSM NSQSGTIGPD HLDHMTPEQI AWLKLQQEFY EEKRRKQEQV VVQQCSLQDM MVHQHGPRGV VRGPPPPYQM TPSEGWAPGG TEPFSDGINM PHSLPPRGMA PHPNMPGSQM RLPGFAGMIN SEMEGPNVPN PASRPGLSGV SWPDDVPKIP DGRNFPPGQG IFSGPGRGER FPNPQGLSEE MFQQQLAEKQ LGLPPGMAME GIRPSMEMNR MIPGSQRHME PGNNPIFPRI PVEGPLSPSR GDFPKGIPPQ MGPGRELEFG MVPSGMKGDV NLNVNMGSNS QMIPQKMREA GAGPEEMLKL RPGGSDMLPA QQKMVPLPFG EHPQQEYGMG PRPFLPMSQG PGSNSGLRNL REPIGPDQRT NSRLSHMPPL PLNPSSNPTS LNTAPPVQRG LGRKPLDISV AGSQVHSPGI NPLKSPTMHQ VQSPMLGSPS GNLKSPQTPS QLAGMLAGPA AAASIKSPPV LGSAAASPVH LKSPSLPAPS PGWTSSPKPP LQSPGIPPNH KAPLTMASPA MLGNVESGGP PPPTASQPAS VNIPGSLPSS TPYTMPPEPT LSQNPLSIMM SRMSKFAMPS STPLYHDAIK TVASSDDDSP PARSPNLPSM NNMPGMGINT QNPRISGPNP VVPMPTLSPM GMTQPLSHSN QMPSPNAVGP NIPPHGVPMG PGLMSHNPIM GHGSQEPPMV PQGRMGFPQG FPPVQSPPQQ VPFPHNGPSG GQGSFPGGMG FPGEGPLGRP SNLPQSSADA ALCKPGGPGG PDSFTVLGNS MPSVFTDPDL QEVIRPGATG IPEFDLSRII PSEKPSQTLQ YFPRGEVPGR KQPQGPGPGF SHMQGMMGEQ APRMGLALPG MGGPGPVGTP DIPLGTAPSM PGHNPMRPPA FLQQGMMGPH HRMMSPAQST MPGQPTLMSN PAAAVGMIPG KDRGPAGLYT HPGPVGSPGM MMSMQGMMGP QQNIMIPPQM RPRGMAADVG MGGFSQGPGN PGNMMF
Genular Protein ID: 3692688952
Symbol: Q1JQ81_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 1426
- Mass: 149302
- Checksum: E8F7AC81730A02C2
- Sequence:
MHSSNPKVRS SPSGNTQSSP KSKQEVMVRP PTVMSPSGNP QLDSKFSNQG KQGGSASQSQ PSPCDSKSGG HTPKALPGPG GSMGLKNGAG NGAKGKGKRE RSISADSFDQ RDPGTPNDDS DIKECNSADH IKSQDSQHTP HSMTPSNATA PRSSTPSHGQ TTATEPTPAQ KTPAKVVYVF STEMANKAAE AVLKGQVETI VSFHIQNISN NKTERSTAPL NTQISALRND PKPLPQQPPA PANQDQNSSQ NTRLQPTPPI PAPAPKPAAP PRPLDRESPG VENKLIPSVG SPASSTPLPP DGTGPNSTPN NRAVTPVSQG SNSSSADPKA PPPPPVSSGE PPTLGENPDG LSQEQLEHRE RSLQTLRDIQ RMLFPDEKEF TGAQSGGPQQ NPGVLDGPQK KPEGPIQAMM AQSQSLGKGP GPRTDVGAPF GPQGHRDVPF SPDEMVPPSM NSQSGTIGPD HLDHMTPEQI AWLKLQQEFY EEKRRKQEQV VVQQCSLQDM MVHQHGPRGV VRGPPPPYQM TPSEGWAPGG TEPFSDGINM PHSLPPRGMA PHPNMPGSQM RLPGFAGMIN SEMEGPNVPN PASRPGLSGV SWPDDVPKIP DGRNFPPGQG IFSGPGRGER FPNPQGLSEE MFQQQLAEKQ LGLPPGMAME GIRPSMEMNR MIPGSQRHME PGNNPIFPRI PVEGPLSPSR GDFPKGIPPQ MGPGRELEFG MVPSGMKGDV NLNVNMGSNS QMIPQKMREA GAGPEEMLKL RPGGSDMLPA QQKMVPLPFG EHPQQEYGMG PRPFLPMSQG PGSNSGLRNL REPIGPDQRT NSRLSHMPPL PLNPSSNPIS LNTAPPVQRG LGRKPLDISV AGSQVHSPGI NPLKSPTMHQ VQSPMLGSPS GNLKSPQTPS QLAGMLAGPA AAASIKSPPV LGSAAASPVH LKSPSLPAPS PGWTSSPKPP LQSPGIPPNH KAPLTMASPA MLGNVESGGP PPPTASQPAS VNIPGSLPSS TPYTMPPEPT LSQNPLSIMM SRMSKFAMPS STPLYHDAIK TVASSDDDSP PARSPNLPSM NNMPGMGINT QNPRISGPNP VVPMPTLSPM GMTQPLSHSN QMPSPNAVGP NIPPHGVPMG PGLMSHNPIM GHGSQEPPMV PQGRMGFPQG FPPVQSPPQQ VPFPHNGPSG GQGSFPGGMG FPGEGPLGRP SNLPQSSADA ALCKPGGPGG PDSFTVLGNS MPSVFTDPDL QEVIRPGATG IPEFDLSRII PSEKPSQTLQ YFPRGEVPGR KQPQGPGPGF SHMQGMMGEQ APRMGLALPG MGGPGPVGTP DIPLGTAPSM PGHNPMRPPA FLQQGMMGPH HRMMSPAQST MPGQPTLMSN PAAAVGMIPG KDRGPAGLYT HPGPVGSPGM MMSMQGMMGP QQNIMIPPQM RPRGMAADVG MGGFSQGPGN PGNMMF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.