Details for: BCYRN1

Gene ID: 618

Symbol: BCYRN1

Ensembl ID: ENSG00000236824

Description: brain cytoplasmic RNA 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.8626
    Cell Significance Index: -15.7100
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 5.3027
    Cell Significance Index: 45.0700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 5.1596
    Cell Significance Index: 163.1900
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 5.0431
    Cell Significance Index: 56.0400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 3.3704
    Cell Significance Index: 152.7700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4725
    Cell Significance Index: 495.9900
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 2.2751
    Cell Significance Index: 14.0600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.1812
    Cell Significance Index: 43.1300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.7205
    Cell Significance Index: 21.3400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.6283
    Cell Significance Index: 34.5600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 1.4475
    Cell Significance Index: 903.9100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.3751
    Cell Significance Index: 1869.7000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.8853
    Cell Significance Index: 55.8000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.4882
    Cell Significance Index: 7.3200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.4727
    Cell Significance Index: 9.4900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3590
    Cell Significance Index: 227.9900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3276
    Cell Significance Index: 62.3500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.2735
    Cell Significance Index: 8.7100
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.2261
    Cell Significance Index: 2.3400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.1620
    Cell Significance Index: 3.5000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1613
    Cell Significance Index: 7.5200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1490
    Cell Significance Index: 274.7100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1429
    Cell Significance Index: 7.4300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.1356
    Cell Significance Index: 4.4400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1346
    Cell Significance Index: 207.2600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.0948
    Cell Significance Index: 2.3700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0894
    Cell Significance Index: 10.2100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0851
    Cell Significance Index: 38.6100
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.0610
    Cell Significance Index: 0.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0587
    Cell Significance Index: 6.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0576
    Cell Significance Index: 16.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0569
    Cell Significance Index: 8.2700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0545
    Cell Significance Index: 102.5900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0046
    Cell Significance Index: 0.7900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.0006
    Cell Significance Index: 0.3400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0018
    Cell Significance Index: -0.9600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0031
    Cell Significance Index: -0.6500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0064
    Cell Significance Index: -4.7500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0218
    Cell Significance Index: -16.5200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0649
    Cell Significance Index: -6.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0717
    Cell Significance Index: -7.3200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0739
    Cell Significance Index: -2.1300
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: -0.0760
    Cell Significance Index: -0.8300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0948
    Cell Significance Index: -3.3200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1143
    Cell Significance Index: -3.1100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1330
    Cell Significance Index: -13.8500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1333
    Cell Significance Index: -18.3000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1578
    Cell Significance Index: -18.0800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2390
    Cell Significance Index: -12.5500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2953
    Cell Significance Index: -3.5200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3272
    Cell Significance Index: -25.1100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3402
    Cell Significance Index: -20.8600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.4363
    Cell Significance Index: -8.7000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4400
    Cell Significance Index: -15.2900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.4921
    Cell Significance Index: -10.2700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5167
    Cell Significance Index: -16.5500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.5257
    Cell Significance Index: -9.0900
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.5497
    Cell Significance Index: -10.8200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.5779
    Cell Significance Index: -15.4300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5836
    Cell Significance Index: -17.1900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5853
    Cell Significance Index: -12.8200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.6027
    Cell Significance Index: -17.7000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.6054
    Cell Significance Index: -15.1200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6122
    Cell Significance Index: -15.6400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6270
    Cell Significance Index: -10.5600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.6558
    Cell Significance Index: -10.9800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6636
    Cell Significance Index: -24.3600
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.6884
    Cell Significance Index: -17.5400
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.6990
    Cell Significance Index: -11.0900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.7249
    Cell Significance Index: -19.0600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.7320
    Cell Significance Index: -19.6200
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.7481
    Cell Significance Index: -10.6500
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.7582
    Cell Significance Index: -8.2600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.7662
    Cell Significance Index: -15.5900
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.7728
    Cell Significance Index: -9.7700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.7835
    Cell Significance Index: -10.6900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.8441
    Cell Significance Index: -21.0500
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.8489
    Cell Significance Index: -12.7000
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.8852
    Cell Significance Index: -12.2400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.9113
    Cell Significance Index: -13.4500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.9323
    Cell Significance Index: -32.7600
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.9363
    Cell Significance Index: -11.8200
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.9388
    Cell Significance Index: -18.3600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.9524
    Cell Significance Index: -15.2800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.9847
    Cell Significance Index: -16.8800
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -1.0306
    Cell Significance Index: -13.4500
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -1.0355
    Cell Significance Index: -17.7000
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -1.1194
    Cell Significance Index: -9.2400
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.1203
    Cell Significance Index: -13.0700
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: -1.1357
    Cell Significance Index: -12.2100
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -1.1388
    Cell Significance Index: -15.8000
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -1.1489
    Cell Significance Index: -16.6800
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -1.1723
    Cell Significance Index: -14.2600
  • Cell Name: pancreatic epsilon cell (CL0005019)
    Fold Change: -1.1840
    Cell Significance Index: -10.9700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -1.2147
    Cell Significance Index: -20.4300
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: -1.2202
    Cell Significance Index: -12.1100
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -1.2225
    Cell Significance Index: -17.1700
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -1.2393
    Cell Significance Index: -11.3000
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -1.2430
    Cell Significance Index: -14.2500
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -1.2651
    Cell Significance Index: -20.4900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Tissue-specific expression:** BCYRN1 is highly expressed in mature astrocytes, microglial cells, and cells of the nasal mucosa, respiratory tract, lens, and eye. This tissue-specific expression pattern highlights the potential importance of BCYRN1 in maintaining tissue homeostasis and function. 2. **Cellular differentiation:** BCYRN1 is expressed in cells undergoing differentiation, such as lens epithelial cells and anterior lens cells. This suggests that BCYRN1 may play a role in regulating cellular differentiation and development. 3. **Immune cell function:** BCYRN1 is expressed in microglial cells, which are a type of immune cell found in the brain. This expression pattern highlights the potential role of BCYRN1 in immune function and regulation. **Pathways and Functions:** 1. **RNA processing and regulation:** BCYRN1 may play a role in regulating RNA processing and stability, particularly in cells involved in differentiation and immune function. 2. **Cellular signaling:** BCYRN1 may be involved in cellular signaling pathways that regulate cell growth, differentiation, and survival. 3. **Immune regulation:** BCYRN1 may contribute to the regulation of immune responses, particularly in the context of neuroinflammation and immune cell function. **Clinical Significance:** 1. **Neurodegenerative diseases:** BCYRN1 may play a role in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, where immune dysfunction and cellular differentiation are key features. 2. **Cancer:** BCYRN1 may contribute to cancer development and progression, particularly in the context of immune evasion and cellular differentiation. 3. **Eye diseases:** BCYRN1 may play a role in the development and progression of eye diseases, such as cataracts and age-related macular degeneration, where cellular differentiation and immune function are key features. 4. **Respiratory diseases:** BCYRN1 may contribute to the development and progression of respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and asthma, where immune dysfunction and cellular differentiation are key features. In conclusion, BCYRN1 is a gene with diverse expression patterns and potential roles in maintaining tissue homeostasis, immune function, and cellular differentiation. Further research is needed to fully elucidate the functions and clinical significance of BCYRN1 in human disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.