BDKRB2 | ENSG00000168398 | NCBI 624

Details for: BDKRB2

Gene ID: 624

Symbol: BDKRB2

Ensembl ID: ENSG00000168398

Description: bradykinin receptor B2

Associated with

Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
G alpha (i) signalling events
(R-HSA-418594)
G alpha (q) signalling events
(R-HSA-416476)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Peptide ligand-binding receptors
(R-HSA-375276)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
Arachidonic acid secretion
(GO:0050482)
Blood circulation
(GO:0008015)
Bradykinin receptor activity
(GO:0004947)
Cell surface receptor signaling pathway
(GO:0007166)
Endosome
(GO:0005768)
Golgi apparatus
(GO:0005794)
G protein-coupled receptor signaling pathway
(GO:0007186)
Inflammatory response
(GO:0006954)
Intracellular membrane-bounded organelle
(GO:0043231)
Intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
(GO:1990127)
Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
(GO:1902239)
Negative regulation of peptidyl-serine phosphorylation
(GO:0033137)
Phosphatidylinositol phospholipase c activity
(GO:0004435)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Protease binding
(GO:0002020)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Regulation of vascular permeability
(GO:0043114)
Regulation of vasoconstriction
(GO:0019229)
Response to salt stress
(GO:0009651)
Smooth muscle contraction
(GO:0006939)
Transmembrane receptor protein tyrosine kinase signaling pathway
(GO:0007169)
Type 1 angiotensin receptor binding
(GO:0031702)
Vasoconstriction
(GO:0042310)
Vasodilation
(GO:0042311)

Other Information

Proteins

B2 bradykinin receptor

Genular Protein ID: 1199126099

Symbol: BKRB2_HUMAN

Name: B2 bradykinin receptor

UniProtKB Accession Codes:

P30411

Database IDs:

Citations:

PubMed ID: 1314587

Title: Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor.

PubMed ID: 1314587

DOI: 10.1016/0006-291x(92)91187-u

PubMed ID: 7916737

Title: Human bradykinin B2 receptor: nucleotide sequence analysis and assignment to chromosome 14.

PubMed ID: 7916737

DOI: 10.1006/geno.1993.1084

PubMed ID: 8394991

Title: Cloned murine bradykinin receptor exhibits a mixed B1 and B2 pharmacological selectivity.

PubMed ID: 8394991

PubMed ID: 1329734

Title: Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene.

PubMed ID: 1329734

DOI: 10.1016/0006-291x(92)90445-q

PubMed ID: 7835885

Title: Structure and chromosomal localization of the gene (BDKRB2) encoding human bradykinin B2 receptor.

PubMed ID: 7835885

DOI: 10.1006/geno.1994.1512

PubMed ID: 7779090

Title: Identification of polymorphic sites of the human bradykinin B2 receptor gene.

PubMed ID: 7779090

DOI: 10.1006/bbrc.1995.1801

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8652530

Title: Structure of the bradykinin B2 receptors' amino terminus.

PubMed ID: 8652530

DOI: 10.1021/bi9601060

PubMed ID: 18672896

Title: Regulation of G protein-coupled receptor activities by the platelet-endothelial cell adhesion molecule, PECAM-1.

PubMed ID: 18672896

DOI: 10.1021/bi8003846

PubMed ID: 11517230

Title: Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.

PubMed ID: 11517230

DOI: 10.1074/jbc.m107024200

Sequence Information:

Length: 391
Mass: 44461
Checksum: 066940ED3D18BB66
Sequence:

MFSPWKISMF LSVREDSVPT TASFSADMLN VTLQGPTLNG TFAQSKCPQV EWLGWLNTIQ 
PPFLWVLFVL ATLENIFVLS VFCLHKSSCT VAEIYLGNLA AADLILACGL PFWAITISNN 
FDWLFGETLC RVVNAIISMN LYSSICFLML VSIDRYLALV KTMSMGRMRG VRWAKLYSLV 
IWGCTLLLSS PMLVFRTMKE YSDEGHNVTA CVISYPSLIW EVFTNMLLNV VGFLLPLSVI 
TFCTMQIMQV LRNNEMQKFK EIQTERRATV LVLVVLLLFI ICWLPFQIST FLDTLHRLGI 
LSSCQDERII DVITQIASFM AYSNSCLNPL VYVIVGKRFR KKSWEVYQGV CQKGGCRSEP 
IQMENSMGTL RTSISVERQI HKLQDWAGSR Q

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: BDKRB2

Associated with

Other Information

Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor. PubMed ID: 1314587

Human bradykinin B2 receptor: nucleotide sequence analysis and assignment to chromosome 14. PubMed ID: 7916737

Cloned murine bradykinin receptor exhibits a mixed B1 and B2 pharmacological selectivity. PubMed ID: 8394991

Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene. PubMed ID: 1329734

Structure and chromosomal localization of the gene (BDKRB2) encoding human bradykinin B2 receptor. PubMed ID: 7835885

Identification of polymorphic sites of the human bradykinin B2 receptor gene. PubMed ID: 7779090

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Structure of the bradykinin B2 receptors' amino terminus. PubMed ID: 8652530

Regulation of G protein-coupled receptor activities by the platelet-endothelial cell adhesion molecule, PECAM-1. PubMed ID: 18672896

Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function. PubMed ID: 11517230