Details for: BFSP1

Gene ID: 631

Symbol: BFSP1

Ensembl ID: ENSG00000125864

Description: beaded filament structural protein 1

Associated with

Other Information

Genular Protein ID: 2195563048

Symbol: BFSP1_HUMAN

Name: Filensin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9628810

Title: Primary sequence, secondary structure, gene structure, and assembly properties suggests that the lens-specific cytoskeletal protein filensin represents a novel class of intermediate filament protein.

PubMed ID: 9628810

DOI: 10.1006/exer.1998.0478

PubMed ID: 9787085

Title: Isolation of the human beaded-filament structural protein 1 gene (BFSP1) and assignment to chromosome 20p11.23-p12.1.

PubMed ID: 9787085

DOI: 10.1006/geno.1998.5478

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7720401

Title: Chromosomal locations of the genes for the beaded filament proteins CP 115 and CP 47.

PubMed ID: 7720401

DOI: 10.3109/02713689508999909

PubMed ID: 10909854

Title: An autosomal dominant posterior polar cataract locus maps to human chromosome 20p12-q12.

PubMed ID: 10909854

DOI: 10.1038/sj.ejhg.5200485

PubMed ID: 17225135

Title: Autosomal recessive juvenile onset cataract associated with mutation in BFSP1.

PubMed ID: 17225135

DOI: 10.1007/s00439-006-0319-6

PubMed ID: 28935373

Title: Human alpha A-crystallin missing N-terminal domain poorly complexes with filensin and phakinin.

PubMed ID: 28935373

DOI: 10.1016/j.bbrc.2017.09.088

PubMed ID: 28450710

Title: Targeted exome sequencing of congenital cataracts related genes: broadening the mutation spectrum and genotype-phenotype correlations in 27 Chinese Han families.

PubMed ID: 28450710

DOI: 10.1038/s41598-017-01182-9

PubMed ID: 30790544

Title: BFSP1 C-terminal domains released by post-translational processing events can alter significantly the calcium regulation of AQP0 water permeability.

PubMed ID: 30790544

DOI: 10.1016/j.exer.2019.02.001

PubMed ID: 24379646

Title: A novel beaded filament structural protein 1 (BFSP1) gene mutation associated with autosomal dominant congenital cataract in a Chinese family.

PubMed ID: 24379646

Sequence Information:

  • Length: 665
  • Mass: 74544
  • Checksum: A99FE174A8B63E9C
  • Sequence:
  • MYRRSYVFQT RKEQYEHADE ASRAAEPERP ADEGWAGATS LAALQGLGER VAAHVQRARA 
    LEQRHAGLRR QLDAFQRLGE LAGPEDALAR QVESNRQRVR DLEAERARLE RQGTEAQRAL 
    DEFRSKYENE CECQLLLKEM LERLNKEADE ALLHNLRLQL EAQFLQDDIS AAKDRHKKNL 
    LEVQTYISIL QQIIHTTPPA SIVTSGMREE KLLTEREVAA LRSQLEEGRE VLSHLQAQRV 
    ELQAQTTTLE QAIKSAHECY DDEIQLYNEQ IETLRKEIEE TERVLEKSSY DCRQLAVAQQ 
    TLKNELDRYH RIIEIEGNRL TSAFIETPIP LFTQSHGVSL STGSGGKDLT RALQDITAAK 
    PRQKALPKNV PRRKEIITKD KTNGALEDAP LKGLEDTKLV QVVLKEESES KFESESKEVS 
    PLTQEGAPED VPDGGQISKG FGKLYRKVKE KVRSPKEPET PTELYTKERH VLVTGDANYV 
    DPRFYVSSIT AKGGVAVSVA EDSVLYDGQV EPSPESPKPP LENGQVGLQE KEDGQPIDQQ 
    PIDKEIEPDG AELEGPEEKR EGEERDEESR RPCAMVTPGA EEPSIPEPPK PAADQDGAEV 
    LGTRSRSLPE KGPPKALAYK TVEVVESIEK ISTESIQTYE ETAVIVETMI GKTKSDKKKS 
    GEKSS

Genular Protein ID: 3361931094

Symbol: B7ZAD2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 526
  • Mass: 58570
  • Checksum: 59DCAA14840E2033
  • Sequence:
  • MLERLNKEAD EALLHNLRLQ LEAQFLQDDI SAAKDRHKKN LLEVQTYISI LQQIIHTTPP 
    ASIVTSGMRE EKLLTEREVA ALRSQLEEGR EVLSHLQAQR VELQAQTTTL EQAIKSAHEC 
    YDDEIQLYNE QIETLRKEIE ETERVLEKSS YDCRQLAVAQ QTLKNELDRY HRIIEIEGNR 
    LTSAFIETPI PLFTQSHGVS LSTGSGGKDL TRALQDITAA KPRQKALPKN VPRRKEIITK 
    DKTNGALEDA PLKGLEDTEL VQVVLKEESE SKFESESKEV SPLTQEGAPE DVPDGGQISK 
    GFGKLYRKVK EKVRSPKEPE TPTELYTKER HVLVTGDANY VDPRFYVSSI TAKGGVAVSV 
    AEDSVLYDGQ VEPSPESPKP PLENGQVGLQ EKEDGQPIDQ QPIDKEIEPD GAELEGPEEK 
    REGEERDEES RRPCAMVTPG AEEPSIPEPP KPAADQDGAE VLGTRSRSLP EKGPPKALAY 
    KTVEVVESIE KISTESIQTY EETAVIVETM IGKTKSDKKK SGEKSS

Genular Protein ID: 2794082462

Symbol: B7Z999_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 526
  • Mass: 58587
  • Checksum: 58857CD7D0233D99
  • Sequence:
  • MLERLNKEAD EALLHNLRLQ LEAQFLQDDI SAAKDRHKKN LLEVQTYISI LQQIIHTTPP 
    ASIVTSGMRE EKLLTEREVA ALRSQLEEGR EVLSHLQAQR VELQAQTTTL EQAIKSAHEC 
    YDDEIQLYNE QIETLRKEIE ETERVLEKSS YDCRQLAVAQ QTLKNELDRY HRIIEIEGNR 
    LTSAFIETPI PLFTQSHGVS LSTGSGGKDL TRALQDMTAA KPRQKALPKN VPRRKEIITK 
    DKTNGALEDA PLKGLEDTKL VQVVLKEESE SKFESESKEV SPLTQEGAPE DVPDGGQISK 
    GFGKLYRKVK EKVRSPKEPE TPTELYTKER HVLVTGDANY VDPRFYVSSI TAKGGVAVSV 
    AEDSVLYDGQ VEPSPESPKP PLENGQVGLQ EKEDGQPIDQ QPIDKEIEPD GAELEGPEEK 
    REGEERDEES RRPCAMVTPG AEEPSIPEPP KPAADQDGAE VLGTRSRSLP EKGPPKALAY 
    KTVEVVESIE KISTESIQTY EETAVIVETM IGKTKSDKKK SGEKSS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.