BGLAP | ENSG00000242252 | NCBI 632

Details for: BGLAP

Gene ID: 632

Symbol: BGLAP

Ensembl ID: ENSG00000242252

Description: bone gamma-carboxyglutamate protein

Associated with

Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
(R-HSA-159854)
Gamma-carboxylation of protein precursors
(R-HSA-159740)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(R-HSA-163841)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Removal of aminoterminal propeptides from gamma-carboxylated proteins
(R-HSA-159782)
Rna polymerase ii transcription
(R-HSA-73857)
Runx2 regulates bone development
(R-HSA-8941326)
Runx2 regulates osteoblast differentiation
(R-HSA-8940973)
Transcriptional regulation by runx2
(R-HSA-8878166)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the golgi apparatus
(R-HSA-159763)
Bone development
(GO:0060348)
Bone mineralization
(GO:0030282)
Brain development
(GO:0007420)
Calcium ion binding
(GO:0005509)
Cell adhesion
(GO:0007155)
Cellular response to growth factor stimulus
(GO:0071363)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to vitamin d
(GO:0071305)
Cellular response to zinc ion starvation
(GO:0034224)
Cognition
(GO:0050890)
Cytoplasm
(GO:0005737)
Dendrite
(GO:0030425)
Dephosphorylation
(GO:0016311)
Endoplasmic reticulum lumen
(GO:0005788)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Glucose homeostasis
(GO:0042593)
Golgi lumen
(GO:0005796)
Hormone activity
(GO:0005179)
Hydroxyapatite binding
(GO:0046848)
Learning or memory
(GO:0007611)
Negative regulation of bone development
(GO:1903011)
Osteoblast development
(GO:0002076)
Osteoblast differentiation
(GO:0001649)
Perikaryon
(GO:0043204)
Positive regulation of neurotransmitter secretion
(GO:0001956)
Protein binding
(GO:0005515)
Regulation of bone mineralization
(GO:0030500)
Regulation of bone resorption
(GO:0045124)
Regulation of cellular response to insulin stimulus
(GO:1900076)
Regulation of osteoclast differentiation
(GO:0045670)
Regulation of testosterone biosynthetic process
(GO:2000224)
Response to activity
(GO:0014823)
Response to estrogen
(GO:0043627)
Response to ethanol
(GO:0045471)
Response to glucocorticoid
(GO:0051384)
Response to gravity
(GO:0009629)
Response to hydroxyisoflavone
(GO:0033594)
Response to macrophage colony-stimulating factor
(GO:0036005)
Response to mechanical stimulus
(GO:0009612)
Response to testosterone
(GO:0033574)
Response to vitamin d
(GO:0033280)
Response to vitamin k
(GO:0032571)
Response to xenobiotic stimulus
(GO:0009410)
Response to zinc ion
(GO:0010043)
Signal transduction
(GO:0007165)
Skeletal system development
(GO:0001501)
Stem cell differentiation
(GO:0048863)
Structural constituent of bone
(GO:0008147)
Structural molecule activity
(GO:0005198)
Type b pancreatic cell proliferation
(GO:0044342)
Vesicle
(GO:0031982)

Other Information

Proteins

Osteocalcin

Genular Protein ID: 2974643023

Symbol: OSTCN_HUMAN

Name: Osteocalcin

UniProtKB Accession Codes:

P02818 Q5TCK6

Database IDs:

Citations:

PubMed ID: 3019668

Title: Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.

PubMed ID: 3019668

DOI: 10.1002/j.1460-2075.1986.tb04440.x

PubMed ID: 2336375

Title: The cDNA and derived amino acid sequences of human and bovine bone Gla protein.

PubMed ID: 2336375

DOI: 10.1093/nar/18.7.1909

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6967872

Title: Isolation and sequence of the vitamin K-dependent protein from human bone. Undercarboxylation of the first glutamic acid residue.

PubMed ID: 6967872

DOI: 10.1016/s0021-9258(18)43554-5

Sequence Information:

Length: 100
Mass: 10963
Checksum: 4DF2A0A80849CB71
Sequence:

MRALTLLALL ALAALCIAGQ AGAKPSGAES SKGAAFVSKQ EGSEVVKRPR RYLYQWLGAP 
VPYPDPLEPR REVCELNPDC DELADHIGFQ EAYRRFYGPV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: BGLAP

Associated with

Other Information

Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones. PubMed ID: 3019668

The cDNA and derived amino acid sequences of human and bovine bone Gla protein. PubMed ID: 2336375

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414