Details for: CEACAM1

Gene ID: 634

Symbol: CEACAM1

Ensembl ID: ENSG00000079385

Description: CEA cell adhesion molecule 1

Associated with

Other Information

Genular Protein ID: 3782896633

Symbol: CEAM1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2537311

Title: Carcinoembryonic antigens: alternative splicing accounts for the multiple mRNAs that code for novel members of the carcinoembryonic antigen family.

PubMed ID: 2537311

DOI: 10.1083/jcb.108.2.267

PubMed ID: 2457922

Title: Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen.

PubMed ID: 2457922

DOI: 10.1073/pnas.85.18.6959

PubMed ID: 2025273

Title: Three novel molecular forms of biliary glycoprotein deduced from cDNA clones from a human leukocyte library.

PubMed ID: 2025273

DOI: 10.1016/s0006-291x(05)80223-2

PubMed ID: 8423792

Title: Human biliary glycoprotein gene: characterization of a family of novel alternatively spliced RNAs and their expressed proteins.

PubMed ID: 8423792

DOI: 10.1128/mcb.13.2.1273-1282.1993

PubMed ID: 8018919

Title: CD66 identifies the biliary glycoprotein (BGP) adhesion molecule: cloning, expression, and adhesion functions of the BGPc splice variant.

PubMed ID: 8018919

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8055923

Title: Transcriptional control of the human biliary glycoprotein gene, a CEA gene family member down-regulated in colorectal carcinomas.

PubMed ID: 8055923

DOI: 10.1111/j.1432-1033.1994.tb19022.x

PubMed ID: 7628460

Title: Characterization and transcriptional activity of the mouse biliary glycoprotein 1 gene, a carcinoembryonic antigen-related gene.

PubMed ID: 7628460

DOI: 10.1111/j.1432-1033.1995.tb20676.x

PubMed ID: 7478590

Title: Association of pp60c-src with biliary glycoprotein (CD66a), an adhesion molecule of the carcinoembryonic antigen family downregulated in colorectal carcinomas.

PubMed ID: 7478590

PubMed ID: 11501563

Title: Redefined nomenclature for members of the carcinoembryonic antigen family.

PubMed ID: 11501563

DOI: 10.1006/excr.1999.4610

PubMed ID: 10436421

Title: Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat.

PubMed ID: 10436421

DOI: 10.1159/000030075

PubMed ID: 11035932

Title: Cell adhesion molecule CEACAM1 associates with paxillin in granulocytes and epithelial and endothelial cells.

PubMed ID: 11035932

DOI: 10.1006/excr.2000.5026

PubMed ID: 11994468

Title: Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes.

PubMed ID: 11994468

DOI: 10.4049/jimmunol.168.10.5139

PubMed ID: 14522961

Title: CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis.

PubMed ID: 14522961

DOI: 10.1074/jbc.m309115200

PubMed ID: 15467833

Title: CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation.

PubMed ID: 15467833

DOI: 10.1172/jci21786

PubMed ID: 16246332

Title: Interactions of DC-SIGN with Mac-1 and CEACAM1 regulate contact between dendritic cells and neutrophils.

PubMed ID: 16246332

DOI: 10.1016/j.febslet.2005.09.089

PubMed ID: 16291724

Title: CEACAM1 functionally interacts with filamin A and exerts a dual role in the regulation of cell migration.

PubMed ID: 16291724

DOI: 10.1242/jcs.02660

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 18424730

Title: Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70.

PubMed ID: 18424730

DOI: 10.4049/jimmunol.180.9.6085

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23696226

Title: CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.

PubMed ID: 23696226

DOI: 10.1002/eji.201242676

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25363763

Title: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

PubMed ID: 25363763

DOI: 10.1038/nature13848

PubMed ID: 26483485

Title: Diverse oligomeric states of CEACAM IgV domains.

PubMed ID: 26483485

DOI: 10.1073/pnas.1509511112

PubMed ID: 16929097

Title: Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae.

PubMed ID: 16929097

DOI: 10.1107/s0907444906020737

Sequence Information:

  • Length: 526
  • Mass: 57560
  • Checksum: CAD1B2328D069AF8
  • Sequence:
  • MGHLSAPLHR VRVPWQGLLL TASLLTFWNP PTTAQLTTES MPFNVAEGKE VLLLVHNLPQ 
    QLFGYSWYKG ERVDGNRQIV GYAIGTQQAT PGPANSGRET IYPNASLLIQ NVTQNDTGFY 
    TLQVIKSDLV NEEATGQFHV YPELPKPSIS SNNSNPVEDK DAVAFTCEPE TQDTTYLWWI 
    NNQSLPVSPR LQLSNGNRTL TLLSVTRNDT GPYECEIQNP VSANRSDPVT LNVTYGPDTP 
    TISPSDTYYR PGANLSLSCY AASNPPAQYS WLINGTFQQS TQELFIPNIT VNNSGSYTCH 
    ANNSVTGCNR TTVKTIIVTE LSPVVAKPQI KASKTTVTGD KDSVNLTCST NDTGISIRWF 
    FKNQSLPSSE RMKLSQGNTT LSINPVKRED AGTYWCEVFN PISKNQSDPI MLNVNYNALP 
    QENGLSPGAI AGIVIGVVAL VALIAVALAC FLHFGKTGRA SDQRDLTEHK PSVSNHTQDH 
    SNDPPNKMNE VTYSTLNFEA QQPTQPTSAS PSLTATEIIY SEVKKQ

Genular Protein ID: 67132752

Symbol: Q3KRG8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 493
  • Mass: 53343
  • Checksum: F19711C3783EE455
  • Sequence:
  • GRGDRAAVLE AFLEPKLSST GEDRASRRHH GAPLSPTSQS ACTLAGLLLT ASLLTFWNPP 
    TTAQLTTESM PFNVAEGKEV LLLVHNLPQQ LFGYSWYKGE RVDGNRQIVG YAIGTQQATP 
    GPANSGRETI YPNASLLIQN VTQNDTGFYT LQVIKSDLVN EEATGQFHVY PELPKPSISS 
    NNSNPVEDKD AVAFTCEPET QDTTYLWWIN NQSLPVSPRL QLSNGNRTLT LLSVTRNDTG 
    PYECEIQNPV SANRSDPVTL NVTYGPDTPT ISPSDTYYRP GANLSLSCYA ASNPPAQYSW 
    LINGTFQQST QELFIPNITV NNSGSYTCHA NNSVTGCNRT TVKTIIVTEL SPVVAKPQIK 
    ASKTTVTGDK DSVDLTCSTN DTGISIRWFF KNQSLPSSER MKLSQGNTTL SINPVKREDA 
    GTYWCEVFNP ISKNQSDPIM LNVNYNALPQ ENGLSPGAIA GIVIGVVALV ALIAVALACF 
    LHFGKTGSSG PLQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.