Details for: BIK

Gene ID: 638

Symbol: BIK

Ensembl ID: ENSG00000100290

Description: BCL2 interacting killer

Associated with

Other Information

Genular Protein ID: 2636869855

Symbol: BIK_HUMAN

Name: Bcl-2-interacting killer

UniProtKB Accession Codes:

Q13323 Q16582 Q6FH93

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 15 Ensembl 1 ExpressionAtlas 1 GO 9 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SIGNOR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7478623

Title: Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins.

PubMed ID: 7478623

PubMed ID: 8816500

Title: Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K.

PubMed ID: 8816500

DOI: 10.1128/mcb.16.10.5857

PubMed ID: 10500065

Title: Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer.

PubMed ID: 10500065

DOI: 10.1016/s0016-5085(99)70341-0

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8521816

Title: A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions.

PubMed ID: 8521816

DOI: 10.1002/j.1460-2075.1995.tb00246.x

PubMed ID: 18953687

Title: A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis.

PubMed ID: 18953687

DOI: 10.1007/s00018-008-8452-0

PubMed ID: 23235460

Title: The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist.

PubMed ID: 23235460

DOI: 10.1038/cddis.2012.178

PubMed ID: 23563182

Title: Polyubiquitination and proteasomal turnover controls the anti-apoptotic activity of Bcl-B.

PubMed ID: 23563182

DOI: 10.1038/onc.2013.99

Sequence Information:

  • Length: 160
  • Mass: 18016
  • Checksum: 89034F4443F5A136
  • Sequence:
    • MSEVRPLSRD ILMETLLYEQ LLEPPTMEVL GMTDSEEDLD PMEDFDSLEC MEGSDALALR 
LACIGDEMDV SLRAPRLAQL SEVAMHSLGL AFIYDQTEDI RDVLRSFMDG FTTLKENIMR 
FWRSPNPGSW VSCEQVLLAL LLLLALLLPL LSGGLHLLLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.