Details for: PRDM1

Gene ID: 639

Symbol: PRDM1

Ensembl ID: ENSG00000057657

Description: PR/SET domain 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 141.3094
    Cell Significance Index: -21.9800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 87.7216
    Cell Significance Index: -22.2500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 59.4943
    Cell Significance Index: -24.1700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 52.2851
    Cell Significance Index: -24.6900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.8433
    Cell Significance Index: -22.0000
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 17.0334
    Cell Significance Index: 239.2400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.6795
    Cell Significance Index: -25.9300
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 7.0682
    Cell Significance Index: 18.9400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.3781
    Cell Significance Index: -19.5900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 6.1468
    Cell Significance Index: 95.1000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.6417
    Cell Significance Index: -22.2600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.2798
    Cell Significance Index: 243.5600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.2529
    Cell Significance Index: 146.0100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6840
    Cell Significance Index: 67.6700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6441
    Cell Significance Index: 581.5300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6227
    Cell Significance Index: 101.2800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4996
    Cell Significance Index: 14.3200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4516
    Cell Significance Index: 23.4600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.4357
    Cell Significance Index: 6.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3229
    Cell Significance Index: 18.1200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3142
    Cell Significance Index: 34.1800
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.2903
    Cell Significance Index: 3.0100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2309
    Cell Significance Index: 6.7800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2287
    Cell Significance Index: 101.1300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1637
    Cell Significance Index: 9.8300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1351
    Cell Significance Index: 9.3500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1306
    Cell Significance Index: 16.7400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1022
    Cell Significance Index: 2.2200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0902
    Cell Significance Index: 2.6000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0711
    Cell Significance Index: 3.3400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0600
    Cell Significance Index: 2.7200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0579
    Cell Significance Index: 7.1200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0481
    Cell Significance Index: 1.6900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0171
    Cell Significance Index: 11.8500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0149
    Cell Significance Index: 8.1500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0063
    Cell Significance Index: 0.8600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0008
    Cell Significance Index: -0.0400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0059
    Cell Significance Index: -11.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0105
    Cell Significance Index: -19.2900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0111
    Cell Significance Index: -2.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0111
    Cell Significance Index: -15.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0124
    Cell Significance Index: -9.1900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0127
    Cell Significance Index: -19.5100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0146
    Cell Significance Index: -9.0900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0160
    Cell Significance Index: -0.4000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0188
    Cell Significance Index: -1.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0214
    Cell Significance Index: -4.2900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0224
    Cell Significance Index: -12.6100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0238
    Cell Significance Index: -8.5400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0276
    Cell Significance Index: -20.9200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0347
    Cell Significance Index: -25.4200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0369
    Cell Significance Index: -23.4600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0429
    Cell Significance Index: -9.0400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0463
    Cell Significance Index: -0.2800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0511
    Cell Significance Index: -23.1800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0618
    Cell Significance Index: -0.6400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0625
    Cell Significance Index: -0.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0702
    Cell Significance Index: -20.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0729
    Cell Significance Index: -12.4500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0818
    Cell Significance Index: -16.2400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1070
    Cell Significance Index: -10.9400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1100
    Cell Significance Index: -12.9700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1468
    Cell Significance Index: -18.9700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1507
    Cell Significance Index: -21.9100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1508
    Cell Significance Index: -7.6200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1548
    Cell Significance Index: -17.7300
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.1587
    Cell Significance Index: -1.1400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1873
    Cell Significance Index: -21.3800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1913
    Cell Significance Index: -2.6100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2080
    Cell Significance Index: -21.6600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2127
    Cell Significance Index: -5.6900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2163
    Cell Significance Index: -4.5900
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.2254
    Cell Significance Index: -2.2600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2441
    Cell Significance Index: -17.2700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2541
    Cell Significance Index: -15.5800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2606
    Cell Significance Index: -17.5300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2645
    Cell Significance Index: -5.4900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2904
    Cell Significance Index: -22.2900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2957
    Cell Significance Index: -12.1200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3060
    Cell Significance Index: -6.0500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3077
    Cell Significance Index: -8.6000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3088
    Cell Significance Index: -9.8900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3122
    Cell Significance Index: -6.6500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3234
    Cell Significance Index: -25.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3280
    Cell Significance Index: -20.1600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3510
    Cell Significance Index: -26.1600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3599
    Cell Significance Index: -15.6500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3868
    Cell Significance Index: -24.3800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3989
    Cell Significance Index: -18.6000
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.4226
    Cell Significance Index: -4.4900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4246
    Cell Significance Index: -18.7800
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.4357
    Cell Significance Index: -3.1400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4756
    Cell Significance Index: -24.9700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4856
    Cell Significance Index: -12.7700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4983
    Cell Significance Index: -18.8700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5107
    Cell Significance Index: -17.8900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5304
    Cell Significance Index: -19.4700
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.5378
    Cell Significance Index: -9.2400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.5865
    Cell Significance Index: -15.6600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.6014
    Cell Significance Index: -15.0200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Histone Methyltransferase Activity:** PRDM1 possesses histone methyltransferase activity, which allows it to modify histone proteins and regulate gene expression. 2. **Transcriptional Regulator:** PRDM1 is a transcriptional regulator that binds to specific DNA sequences and modulates the expression of target genes involved in immune cell development and function. 3. **Immune Cell Specificity:** PRDM1 is significantly expressed in various immune cells, including T cells, B cells, and natural killer cells, and is involved in their development, function, and homeostasis. 4. **Signaling Pathways:** PRDM1 is involved in numerous signaling pathways that regulate immune cell development, function, and homeostasis, including the adaptive and innate immune responses. **Pathways and Functions:** 1. **Adaptive Immune Response:** PRDM1 regulates the development and function of T cells, including CD4+ and CD8+ T cells, and is involved in the adaptive immune response. 2. **Innate Immune Response:** PRDM1 is also involved in the innate immune response, regulating the development and function of natural killer cells and other innate immune cells. 3. **Cell Fate Commitment:** PRDM1 regulates the cell fate commitment of immune cells, including the specification of primordial germ cells and the development of trophoblast giant cells. 4. **Transcriptional Regulation:** PRDM1 regulates the expression of target genes involved in immune cell development and function, including the regulation of transcription by RNA polymerase II and the negative regulation of gene expression. **Clinical Significance:** 1. **Immunodeficiency Disorders:** PRDM1 mutations or dysregulation have been implicated in immunodeficiency disorders, including severe combined immunodeficiency (SCID) and other primary immunodeficiency diseases. 2. **Cancer:** PRDM1 has been implicated in cancer development and progression, particularly in T-cell lymphomas and other hematological malignancies. 3. **Autoimmune Diseases:** PRDM1 has been implicated in autoimmune diseases, including rheumatoid arthritis and multiple sclerosis, where it regulates the expression of genes involved in immune cell function and autoimmunity. 4. **Vaccine Development:** PRDM1 is a potential target for vaccine development, particularly for vaccines against infectious diseases and cancer. In conclusion, PRDM1 is a critical regulator of immune cell development and function, and its dysregulation has been implicated in various immunodeficiency disorders, cancers, and autoimmune diseases. Further research is needed to fully understand the functions of PRDM1 and its potential therapeutic applications.

Genular Protein ID: 4161602001

Symbol: PRDM1_HUMAN

Name: PR domain zinc finger protein 1

UniProtKB Accession Codes:

O75626 B2REA6 E1P5E0 Q86WM7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 11 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 40 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PIRSF 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 3 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1851123

Title: Identification and characterization of a novel repressor of beta-interferon gene expression.

PubMed ID: 1851123

DOI: 10.1101/gad.5.5.868

PubMed ID: 12626569

Title: Identification of a functionally impaired positive regulatory domain I binding factor 1 transcription repressor in myeloma cell lines.

PubMed ID: 12626569

DOI: 10.4049/jimmunol.170.6.3125

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21421998

Title: NANOS3 function in human germ cell development.

PubMed ID: 21421998

DOI: 10.1093/hmg/ddr114

PubMed ID: 22555612

Title: SUMOylation of Blimp-1 is critical for plasma cell differentiation.

PubMed ID: 22555612

DOI: 10.1038/embor.2012.60

PubMed ID: 24613396

Title: DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation.

PubMed ID: 24613396

DOI: 10.1016/j.devcel.2014.01.028

PubMed ID: 24968003

Title: BLMP-1/Blimp-1 regulates the spatiotemporal cell migration pattern in C. elegans.

PubMed ID: 24968003

DOI: 10.1371/journal.pgen.1004428

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 32417234

Title: LDB1 and the SWI/SNF complex participate in both transcriptional activation and repression by Caenorhabditis elegans BLIMP1/PRDM1.

PubMed ID: 32417234

DOI: 10.1016/j.bbagrm.2020.194577

PubMed ID: 28842558

Title: HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells.

PubMed ID: 28842558

DOI: 10.1038/s41467-017-00476-w

Sequence Information:

  • Length: 825
  • Mass: 91771
  • Checksum: 07B389BACCD6172F
  • Sequence:
    • MLDICLEKRV GTTLAAPKCN SSTVRFQGLA EGTKGTMKMD MEDADMTLWT EAEFEEKCTY 
IVNDHPWDSG ADGGTSVQAE ASLPRNLLFK YATNSEEVIG VMSKEYIPKG TRFGPLIGEI 
YTNDTVPKNA NRKYFWRIYS RGELHHFIDG FNEEKSNWMR YVNPAHSPRE QNLAACQNGM 
NIYFYTIKPI PANQELLVWY CRDFAERLHY PYPGELTMMN LTQTQSSLKQ PSTEKNELCP 
KNVPKREYSV KEILKLDSNP SKGKDLYRSN ISPLTSEKDL DDFRRRGSPE MPFYPRVVYP 
IRAPLPEDFL KASLAYGIER PTYITRSPIP SSTTPSPSAR SSPDQSLKSS SPHSSPGNTV 
SPVGPGSQEH RDSYAYLNAS YGTEGLGSYP GYAPLPHLPP AFIPSYNAHY PKFLLPPYGM 
NCNGLSAVSS MNGINNFGLF PRLCPVYSNL LGGGSLPHPM LNPTSLPSSL PSDGARRLLQ 
PEHPREVLVP APHSAFSFTG AAASMKDKAC SPTSGSPTAG TAATAEHVVQ PKATSAAMAA 
PSSDEAMNLI KNKRNMTGYK TLPYPLKKQN GKIKYECNVC AKTFGQLSNL KVHLRVHSGE 
RPFKCQTCNK GFTQLAHLQK HYLVHTGEKP HECQVCHKRF SSTSNLKTHL RLHSGEKPYQ 
CKVCPAKFTQ FVHLKLHKRL HTRERPHKCS QCHKNYIHLC SLKVHLKGNC AAAPAPGLPL 
EDLTRINEEI EKFDISDNAD RLEDVEDDIS VISVVEKEIL AVVRKEKEET GLKVSLQRNM 
GNGLLSSGCS LYESSDLPLM KLPPSNPLPL VPVKVKQETV EPMDP

Genular Protein ID: 3231884389

Symbol: Q5T4E8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5T4E8

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 9 Gene3D 2 HOGENOM 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PROSITE 5 PROSITE-ProRule 1 Pfam 2 RefSeq 2 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 789
  • Mass: 87991
  • Checksum: 6A1FEBEAD309BC7D
  • Sequence:
    • MKMDMEDADM TLWTEAEFEE KCTYIVNDHP WDSGADGGTS VQAEASLPRN LLFKYATNSE 
EVIGVMSKEY IPKGTRFGPL IGEIYTNDTV PKNANRKYFW RIYSRGELHH FIDGFNEEKS 
NWMRYVNPAH SPREQNLAAC QNGMNIYFYT IKPIPANQEL LVWYCRDFAE RLHYPYPGEL 
TMMNLTQTQS SLKQPSTEKN ELCPKNVPKR EYSVKEILKL DSNPSKGKDL YRSNISPLTS 
EKDLDDFRRR GSPEMPFYPR VVYPIRAPLP EDFLKASLAY GIERPTYITR SPIPSSTTPS 
PSARSSPDQS LKSSSPHSSP GNTVSPVGPG SQEHRDSYAY LNASYGTEGL GSYPGYAPLP 
HLPPAFIPSY NAHYPKFLLP PYGMNCNGLS AVSSMNGINN FGLFPRLCPV YSNLLGGGSL 
PHPMLNPTSL PSSLPSDGAR RLLQPEHPRE VLVPAPHSAF SFTGAAASMK DKACSPTSGS 
PTAGTAATAE HVVQPKATSA AMAAPSSDEA MNLIKNKRNM TGYKTLPYPL KKQNGKIKYE 
CNVCAKTFGQ LSNLKVHLRV HSGERPFKCQ TCNKGFTQLA HLQKHYLVHT GEKPHECQVC 
HKRFSSTSNL KTHLRLHSGE KPYQCKVCPA KFTQFVHLKL HKRLHTRERP HKCSQCHKNY 
IHLCSLKVHL KGNCAAAPAP GLPLEDLTRI NEEIEKFDIS DNADRLEDVE DDISVISVVE 
KEILAVVRKE KEETGLKVSL QRNMGNGLLS SGCSLYESSD LPLMKLPPSN PLPLVPVKVK 
QETVEPMDP

Genular Protein ID: 1467833650

Symbol: B4DW27_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DW27

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 629
  • Mass: 70046
  • Checksum: 17E63BE19CC57AE7
  • Sequence:
    • MEKIYSRGEL HHFIDGFNEE KSNWMRYVNP AHSPREQNLA ACQNGMNIYF YTIKPIPANQ 
ELLVWYCRDF AERLHYPYPG ELTMMNLTQT QSSLKQPSTE KNELCPKNVP KREYSVKEIL 
KLDSNPSKGK DLYRSNISPL TSEKDLDDFR RRGSPEMPFY PRVVYPIRAP LPEDFLKASL 
AYGIERPTYI TRSPIPSSTT PSPSARSSPD QSLKSSSPHS SPGNTVSPVG PGSQEHRDSY 
AYLNASYGTE GLGSYPGYAP LPHLPPAFIP SYNAHYPKFL LPPYGMNCNG LSAVSSMNGI 
NNFGLFPRLC PVYSNLLGGG SLPHPMLNPT SLPSSLPSDG ARRLLQPEHP REVLVPAPHS 
AFSFTGAAAS MKDKACSPTS GSPTAGTAAT AEHVVQPKAT SAAMAAPSSD EAMNLIKNKR 
NMTGYKTLPY PLKKQNGKIK YECNVCAKTF GQLSNLKVHL RVHSGERPFK CQTCNKGFTQ 
LAHLQKHYLV HTGEKPHECQ VCHKRFSSTS NLKTHLRLHS GEKPYQCKVC PAKFTQFVHL 
KLHKRLHTRE RPHKCSQCHK NYIHLCSLKV HLKGNCAAAP APGLPLEDLT RINEEIEKFD 
ISDNADRLED VEDDISVISV VEKEILAVV

Genular Protein ID: 3327863494

Symbol: A0A3B3IU23_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A3B3IU23

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 9 Gene3D 2 GeneTree 1 HGNC 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 839
  • Mass: 93296
  • Checksum: 8802B62F65B12C0A
  • Sequence:
    • MTPGILGHWT VCPEHFSAMR GKARDCSEAA PKCNSSTVRF QGLAEGTKGT MKMDMEDADM 
TLWTEAEFEE KCTYIVNDHP WDSGADGGTS VQAEASLPRN LLFKYATNSE EVIGVMSKEY 
IPKGTRFGPL IGEIYTNDTV PKNANRKYFW RIYSRGELHH FIDGFNEEKS NWMRYVNPAH 
SPREQNLAAC QNGMNIYFYT IKPIPANQEL LVWYCRDFAE RLHYPYPGEL TMMNLTQTQS 
SLKQPSTEKN ELCPKNVPKR EYSVKEILKL DSNPSKGKDL YRSNISPLTS EKDLDDFRRR 
GSPEMPFYPR VVYPIRAPLP EDFLKASLAY GIERPTYITR SPIPSSTTPS PSARSSPDQS 
LKSSSPHSSP GNTVSPVGPG SQEHRDSYAY LNASYGTEGL GSYPGYAPLP HLPPAFIPSY 
NAHYPKFLLP PYGMNCNGLS AVSSMNGINN FGLFPRLCPV YSNLLGGGSL PHPMLNPTSL 
PSSLPSDGAR RLLQPEHPRE VLVPAPHSAF SFTGAAASMK DKACSPTSGS PTAGTAATAE 
HVVQPKATSA AMAAPSSDEA MNLIKNKRNM TGYKTLPYPL KKQNGKIKYE CNVCAKTFGQ 
LSNLKVHLRV HSGERPFKCQ TCNKGFTQLA HLQKHYLVHT GEKPHECQVC HKRFSSTSNL 
KTHLRLHSGE KPYQCKVCPA KFTQFVHLKL HKRLHTRERP HKCSQCHKNY IHLCSLKVHL 
KGNCAAAPAP GLPLEDLTRI NEEIEKFDIS DNADRLEDVE DDISVISVVE KEILAVVRKE 
KEETGLKVSL QRNMGNGLLS SGCSLYESSD LPLMKLPPSN PLPLVPVKVK QETVEPMDP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.