Details for: MCUR1

Gene ID: 63933

Symbol: MCUR1

Ensembl ID: ENSG00000050393

Description: mitochondrial calcium uniporter regulator 1

Associated with

Other Information

Genular Protein ID: 3500958740

Symbol: MCUR1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96AQ8 Q96JS7 Q9H7F8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 1 SMR 1 STRING 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 23178883

Title: MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism.

PubMed ID: 23178883

DOI: 10.1038/ncb2622

PubMed ID: 26341627

Title: Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.

PubMed ID: 26341627

DOI: 10.15252/embr.201540436

PubMed ID: 25565209

Title: CCDC90A (MCUR1) is a cytochrome c oxidase assembly factor and not a regulator of the mitochondrial calcium uniporter.

PubMed ID: 25565209

DOI: 10.1016/j.cmet.2014.12.004

PubMed ID: 26445506

Title: MCUR1, CCDC90A, is a regulator of the mitochondrial calcium uniporter.

PubMed ID: 26445506

DOI: 10.1016/j.cmet.2015.09.015

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27184846

Title: MCUR1 is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics.

PubMed ID: 27184846

DOI: 10.1016/j.celrep.2016.04.050

PubMed ID: 26976564

Title: Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition.

PubMed ID: 26976564

DOI: 10.1073/pnas.1602264113

Sequence Information:

  • Length: 359
  • Mass: 39694
  • Checksum: 488A2ABECFA2780B
  • Sequence:
    • MDCGSVGGQR TQRLPGRQRL LFLPVGLSGR PGGSETSARR CLSALSDGLG ALRPRAPAAR 
GGVSRASPLL LLLLVPSPRL AAAAPRRQLG DWERSRLGYA APPAGRSSAW RCSPGVAAAA 
GALPQYHGPA PALVSCRREL SLSAGSLQLE RKRRDFTSSG SRKLYFDTHA LVCLLEDNGF 
ATQQAEIIVS ALVKILEANM DIVYKDMVTK MQQEITFQQV MSQIANVKKD MIILEKSEFS 
ALRAENEKIK LELHQLKQQV MDEVIKVRTD TKLDFNLEKS RVKELYSLNE KKLLELRTEI 
VALHAQQDRA LTQTDRKIET EVAGLKTMLE SHKLDNIKYL AGSIFTCLTV ALGFYRLWI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.