Details for: PCIF1

Gene ID: 63935

Symbol: PCIF1

Ensembl ID: ENSG00000100982

Description: phosphorylated CTD interacting factor 1

Associated with

Other Information

Genular Protein ID: 3457624435

Symbol: CAPAM_HUMAN

Name: mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12565871

Title: PCIF1, a novel human WW domain-containing protein, interacts with the phosphorylated RNA polymerase II.

PubMed ID: 12565871

DOI: 10.1016/s0006-291x(02)03015-2

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 18294453

Title: Human phosphorylated CTD-interacting protein, PCIF1, negatively modulates gene expression by RNA polymerase II.

PubMed ID: 18294453

DOI: 10.1016/j.bbrc.2008.02.042

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 30487554

Title: Cap-specific, terminal N6-methylation by a mammalian m6Am methyltransferase.

PubMed ID: 30487554

DOI: 10.1038/s41422-018-0117-4

PubMed ID: 31279658

Title: Identification of the m6Am methyltransferase PCIF1 reveals the location and functions of m6Am in the transcriptome.

PubMed ID: 31279658

DOI: 10.1016/j.molcel.2019.06.006

PubMed ID: 31279659

Title: PCIF1 catalyzes m6Am mRNA methylation to regulate gene expression.

PubMed ID: 31279659

DOI: 10.1016/j.molcel.2019.05.030

PubMed ID: 33428944

Title: Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima.

PubMed ID: 33428944

DOI: 10.1016/j.jbc.2021.100270

PubMed ID: 30467178

Title: Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase.

PubMed ID: 30467178

DOI: 10.1126/science.aav0080

Sequence Information:

  • Length: 704
  • Mass: 80670
  • Checksum: 83647BC8408BA9E9
  • Sequence:
  • MANENHGSPR EEASLLSHSP GTSNQSQPCS PKPIRLVQDL PEELVHAGWE KCWSRRENRP 
    YYFNRFTNQS LWEMPVLGQH DVISDPLGLN ATPLPQDSSL VETPPAENKP RKRQLSEEQP 
    SGNGVKKPKI EIPVTPTGQS VPSSPSIPGT PTLKMWGTSP EDKQQAALLR PTEVYWDLDI 
    QTNAVIKHRG PSEVLPPHPE VELLRSQLIL KLRQHYRELC QQREGIEPPR ESFNRWMLER 
    KVVDKGSDPL LPSNCEPVVS PSMFREIMND IPIRLSRIKF REEAKRLLFK YAEAARRLIE 
    SRSASPDSRK VVKWNVEDTF SWLRKDHSAS KEDYMDRLEH LRRQCGPHVS AAAKDSVEGI 
    CSKIYHISLE YVKRIREKHL AILKENNISE EVEAPEVEPR LVYCYPVRLA VSAPPMPSVE 
    MHMENNVVCI RYKGEMVKVS RNYFSKLWLL YRYSCIDDSA FERFLPRVWC LLRRYQMMFG 
    VGLYEGTGLQ GSLPVHVFEA LHRLFGVSFE CFASPLNCYF RQYCSAFPDT DGYFGSRGPC 
    LDFAPLSGSF EANPPFCEEL MDAMVSHFER LLESSPEPLS FIVFIPEWRE PPTPALTRME 
    QSRFKRHQLI LPAFEHEYRS GSQHICKKEE MHYKAVHNTA VLFLQNDPGF AKWAPTPERL 
    QELSAAYRQS GRSHSSGSSS SSSSEAKDRD SGREQGPSRE PHPT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.