PRDM14 | ENSG00000147596 | NCBI 63978

Details for: PRDM14

Gene ID: 63978

Symbol: PRDM14

Ensembl ID: ENSG00000147596

Description: PR/SET domain 14

Associated with

Developmental biology
(R-HSA-1266738)
Transcriptional regulation of pluripotent stem cells
(R-HSA-452723)
Cell fate specification
(GO:0001708)
Cell morphogenesis
(GO:0000902)
Chromatin dna binding
(GO:0031490)
Embryo implantation
(GO:0007566)
Epigenetic regulation of gene expression
(GO:0040029)
Fertilization
(GO:0009566)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Germ-line stem cell population maintenance
(GO:0030718)
Germ cell development
(GO:0007281)
Homeostasis of number of cells within a tissue
(GO:0048873)
Inner cell mass cell fate commitment
(GO:0001827)
Intracellular membrane-bounded organelle
(GO:0043231)
Metal ion binding
(GO:0046872)
Methylation
(GO:0032259)
Methyltransferase activity
(GO:0008168)
Negative regulation of fibroblast growth factor receptor signaling pathway
(GO:0040037)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of flagellated sperm motility
(GO:1902093)
Positive regulation of stem cell population maintenance
(GO:1902459)
Protein binding
(GO:0005515)
Regulation of dna methylation
(GO:0044030)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna binding
(GO:0003723)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)

Other Information

Proteins

PR domain zinc finger protein 14

Genular Protein ID: 3594135488

Symbol: PRD14_HUMAN

Name: PR domain zinc finger protein 14

UniProtKB Accession Codes:

Q9GZV8 Q86UX9

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17942894

Title: Gene amplification and overexpression of PRDM14 in breast cancers.

PubMed ID: 17942894

DOI: 10.1158/0008-5472.can-06-4111

PubMed ID: 20953172

Title: A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.

PubMed ID: 20953172

DOI: 10.1038/nature09531

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 27281218

Title: Co-repressor CBFA2T2 regulates pluripotency and germline development.

PubMed ID: 27281218

DOI: 10.1038/nature18004

Sequence Information:

Length: 571
Mass: 64062
Checksum: 60D5ACC96DADE500
Sequence:

MALPRPSEAV PQDKVCYPPE SSPQNLAAYY TPFPSYGHYR NSLATVEEDF QPFRQLEAAA 
SAAPAMPPFP FRMAPPLLSP GLGLQREPLY DLPWYSKLPP WYPIPHVPRE VPPFLSSSHE 
YAGASSEDLG HQIIGGDNES GPCCGPDTLI PPPPADASLL PEGLRTSQLL PCSPSKQSED 
GPKPSNQEGK SPARFQFTEE DLHFVLYGVT PSLEHPASLH HAISGLLVPP DSSGSDSLPQ 
TLDKDSLQLP EGLCLMQTVF GEVPHFGVFC SSFIAKGVRF GPFQGKVVNA SEVKTYGDNS 
VMWEIFEDGH LSHFIDGKGG TGNWMSYVNC ARFPKEQNLV AVQCQGHIFY ESCKEIHQNQ 
ELLVWYGDCY EKFLDIPVSL QVTEPGKQPS GPSEESAEGY RCERCGKVFT YKYYRDKHLK 
YTPCVDKGDR KFPCSLCKRS FEKRDRLRIH ILHVHEKHRP HKCSTCGKCF SQSSSLNKHM 
RVHSGDRPYQ CVYCTKRFTA SSILRTHIRQ HSGEKPFKCK YCGKSFASHA AHDSHVRRSH 
KEDDGCSCSI CGKIFSDQET FYSHMKFHED Y

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: PRDM14

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Gene amplification and overexpression of PRDM14 in breast cancers. PubMed ID: 17942894

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. PubMed ID: 20953172

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692