Kit | ENSRNOG00000002227 | NCBI 64030

Details for: Kit

Gene ID: 64030

Symbol: Kit

Ensembl ID: ENSRNOG00000002227

Description: KIT proto-oncogene receptor tyrosine kinase

Associated with

Intracellular signaling by second messengers
(R-RNO-9006925)
Mapk1/mapk3 signaling
(R-RNO-5684996)
Mapk family signaling cascades
(R-RNO-5683057)
Negative regulation of the pi3k/akt network
(R-RNO-199418)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-RNO-6811558)
Pip3 activates akt signaling
(R-RNO-1257604)
Raf/map kinase cascade
(R-RNO-5673001)
Regulation of kit signaling
(R-RNO-1433559)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by scf-kit
(R-RNO-1433557)
Signal transduction
(R-RNO-162582)
Acrosomal vesicle
(GO:0001669)
Actin cytoskeleton organization
(GO:0030036)
Atp binding
(GO:0005524)
B cell differentiation
(GO:0030183)
Cell-cell junction
(GO:0005911)
Cell chemotaxis
(GO:0060326)
Cell population proliferation
(GO:0008283)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine binding
(GO:0019955)
Detection of mechanical stimulus involved in sensory perception of sound
(GO:0050910)
Developmental pigmentation
(GO:0048066)
Digestive tract development
(GO:0048565)
Ectopic germ cell programmed cell death
(GO:0035234)
Embryonic hemopoiesis
(GO:0035162)
Epithelial cell proliferation
(GO:0050673)
Erythrocyte differentiation
(GO:0030218)
Erythropoietin-mediated signaling pathway
(GO:0038162)
External side of plasma membrane
(GO:0009897)
Extracellular space
(GO:0005615)
Fc receptor signaling pathway
(GO:0038093)
Fibrillar center
(GO:0001650)
Germ cell migration
(GO:0008354)
Glycosphingolipid metabolic process
(GO:0006687)
Growth factor binding
(GO:0019838)
Hematopoietic progenitor cell differentiation
(GO:0002244)
Hematopoietic stem cell migration
(GO:0035701)
Hemopoiesis
(GO:0030097)
Immature b cell differentiation
(GO:0002327)
Inflammatory response
(GO:0006954)
Intracellular signal transduction
(GO:0035556)
Kit signaling pathway
(GO:0038109)
Lamellipodium assembly
(GO:0030032)
Lymphoid progenitor cell differentiation
(GO:0002320)
Male gonad development
(GO:0008584)
Mast cell chemotaxis
(GO:0002551)
Mast cell degranulation
(GO:0043303)
Mast cell differentiation
(GO:0060374)
Mast cell proliferation
(GO:0070662)
Megakaryocyte development
(GO:0035855)
Melanocyte adhesion
(GO:0097326)
Melanocyte differentiation
(GO:0030318)
Melanocyte migration
(GO:0097324)
Metal ion binding
(GO:0046872)
Multicellular organism development
(GO:0007275)
Myeloid progenitor cell differentiation
(GO:0002318)
Negative regulation of developmental process
(GO:0051093)
Negative regulation of programmed cell death
(GO:0043069)
Negative regulation of reproductive process
(GO:2000242)
Ovarian follicle development
(GO:0001541)
Phosphorylation
(GO:0016310)
Pigmentation
(GO:0043473)
Plasma membrane
(GO:0005886)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of colon smooth muscle contraction
(GO:1904343)
Positive regulation of dendritic cell cytokine production
(GO:0002732)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of long-term neuronal synaptic plasticity
(GO:0048170)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of map kinase activity
(GO:0043406)
Positive regulation of mast cell cytokine production
(GO:0032765)
Positive regulation of mast cell proliferation
(GO:0070668)
Positive regulation of notch signaling pathway
(GO:0045747)
Positive regulation of pseudopodium assembly
(GO:0031274)
Positive regulation of pyloric antrum smooth muscle contraction
(GO:0120072)
Positive regulation of receptor signaling pathway via jak-stat
(GO:0046427)
Positive regulation of small intestine smooth muscle contraction
(GO:1904349)
Positive regulation of tyrosine phosphorylation of stat protein
(GO:0042531)
Positive regulation of vascular associated smooth muscle cell differentiation
(GO:1905065)
Programmed cell death
(GO:0012501)
Protease binding
(GO:0002020)
Protein homodimerization activity
(GO:0042803)
Protein tyrosine kinase activity
(GO:0004713)
Regulation of bile acid metabolic process
(GO:1904251)
Regulation of cell shape
(GO:0008360)
Response to cadmium ion
(GO:0046686)
Response to radiation
(GO:0009314)
Sh2 domain binding
(GO:0042169)
Somatic stem cell population maintenance
(GO:0035019)
Spermatid development
(GO:0007286)
Spermatogenesis
(GO:0007283)
Stem cell differentiation
(GO:0048863)
Stem cell factor receptor activity
(GO:0005020)
T cell differentiation
(GO:0030217)
Tongue development
(GO:0043586)
Transmembrane receptor protein tyrosine kinase activity
(GO:0004714)
Visual learning
(GO:0008542)

Other Information

Proteins

Q63116_RAT

Genular Protein ID: 2031365059

Symbol: Q63116_RAT

Name: N/A

UniProtKB Accession Codes:

Q63116 A6JCZ9

Database IDs:

Citations:

PubMed ID: 1912577

Title: Characterization of Ws mutant allele of rats: a 12-base deletion in tyrosine kinase domain of c-kit gene.

PubMed ID: 1912577

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

Sequence Information:

Length: 978
Mass: 109342
Checksum: 0958C33F19889051
Sequence:

MRGARGAWDL LCVLLVLLRG QTGTSQPSAS PGEPSPPSIQ PAQSELIVEA GDTIRLTCTD 
PAFVKWTFEI LDVRIENKQS EWIREKAEAT HTGKYTCVSG SGLRSSIYVF VRDPAVLFLV 
GLPLFGKEDN DALVRCPLTD PQVSNYSLIE CDGKSLPTDL KFVPNPKAGI TIKNVKRAYH 
RLCIRCAAQR EGKWMRSDKF TLKVRAAIKA IPVVSVPETS HLLKEGDTFT VICTIKDVST 
SVDSMWIKLN PQPQSKAQVK RNSWHQGDFN YERQETLTIS SARVNDSGVF MCYANNTFGS 
ANVTTTLKVV EKGFINIFPV KNTTVFVTDG ENVDLVVEFE AYPKPEHQQW IYMNRTPTNR 
GEDYVKSDNQ SNIRYVNELR LTRLKGTEGG TYTFLVSNSD VSASVTFDVY VNTKPEILTY 
DRLMNGRLQC VAAGFPEPTI DWYFCTGAEQ RCTVPVPPVD VQIQNASVSP FGKLVVQSSI 
DSSVFRHNGT VECKASNAVG KSSAFFNFAF KGNSKEQIQP HTLFTPLLIG FVVTAGLMGI 
IVMVLAYKYL QKPMYEVQWK VVEEINGNNY VYIDPTQLPY DHKWEFPRNR LSFGKTLGAG 
AFGKVVEATA YGLIKSDAAM TVAVKMLKPS AHLTEREALM SELKVLSYLG NHMNIVNLLG 
ACTVGGPTLV ITEYCCYGDL LNFLRRKRDS FIFSKQEEQA DAALYKNLLH SKESSCDSSN 
EYMDMKPGVS YVVPTKTDKR RSARIDSYIE RDVTPAIMED DELALDLEDL LSFSYQVAKG 
MAFLASKNCI HRDLAARNIL LTHGRITKIC DFGLARDIRN DSNYVVKGNA RLPVKWMAPE 
SIFNCVYTFE SDVWSYGIFL WELFSLGSSP YPGMPVDSKF YKMIKEGFRM LSPEHAPAAM 
YEVMKTCWDA DPLKRPTFKQ VVQLIEKQIS DSSKHIYSNL ANCNPNPENP VVVDHSVRVN 
SVGSSTSSTQ PLLVHEDA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.