Details for: Sv2a

Gene ID: 64051

Symbol: Sv2a

Ensembl ID: ENSMUSG00000038486

Description: synaptic vesicle glycoprotein 2a

Associated with

Other Information

Genular Protein ID: 2050909370

Symbol: SV2A_MOUSE

Name: Synaptic vesicle glycoprotein 2A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10624962

Title: SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release.

PubMed ID: 10624962

DOI: 10.1016/s0896-6273(00)81046-6

PubMed ID: 12693553

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 12693553

DOI: 10.1093/dnares/10.1.35

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10611374

Title: Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A).

PubMed ID: 10611374

DOI: 10.1073/pnas.96.26.15268

PubMed ID: 11483953

Title: SV2 modulates the size of the readily releasable pool of secretory vesicles.

PubMed ID: 11483953

DOI: 10.1038/35087000

PubMed ID: 12209837

Title: Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.

PubMed ID: 12209837

DOI: 10.1002/cne.10281

PubMed ID: 12687700

Title: Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina.

PubMed ID: 12687700

DOI: 10.1002/cne.10636

PubMed ID: 16436618

Title: Synaptic vesicle protein 2 enhances release probability at quiescent synapses.

PubMed ID: 16436618

DOI: 10.1523/jneurosci.2699-05.2006

PubMed ID: 16543415

Title: SV2 is the protein receptor for botulinum neurotoxin A.

PubMed ID: 16543415

DOI: 10.1126/science.1123654

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 18815274

Title: Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.

PubMed ID: 18815274

DOI: 10.1091/mbc.e08-07-0765

PubMed ID: 21483489

Title: Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.

PubMed ID: 21483489

DOI: 10.1371/journal.ppat.1002008

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 742
  • Mass: 82647
  • Checksum: 1074857FD13ED894
  • Sequence:
  • MEEGFRDRAA FIRGAKDIAK EVKKHAAKKV VKGLDRVQDE YSRRSYSRFE EEDDDDDFPA 
    PADGYYRGEG AQDEEEGGAS SDATEGHDED DEIYEGEYQG IPRAESGGKG ERMADGAPLA 
    GVRGGLSDGE GPPGGRGEAQ RRKDREELAQ QYETILRECG HGRFQWTLYF VLGLALMADG 
    VEVFVVGFVL PSAEKDMCLS DSNKGMLGLI VYLGMMVGAF LWGGLADRLG RRQCLLISLS 
    VNSVFAFFSS FVQGYGTFLF CRLLSGVGIG GSIPIVFSYF SEFLAQEKRG EHLSWLCMFW 
    MIGGVYAAAM AWAIIPHYGW SFQMGSAYQF HSWRVFVLVC AFPSVFAIGA LTTQPESPRF 
    FLENGKHDEA WMVLKQVHDT NMRAKGHPER VFSVTHIKTI HQEDELIEIQ SDTGTWYQRW 
    GVRALSLGGQ VWGNFLSCFS PEYRRITLMM MGVWFTMSFS YYGLTVWFPD MIRHLQAVDY 
    AARTKVFPGE RVEHVTFNFT LENQIHRGGQ YFNDKFIGLR LKSVSFEDSL FEECYFEDVT 
    SSNTFFRNCT FINTVFYNTD LFEYKFVNSR LVNSTFLHNK EGCPLDVTGT GEGAYMVYFV 
    SFLGTLAVLP GNIVSALLMD KIGRLRMLAG SSVLSCVSCF FLSFGNSESA MIALLCLFGG 
    VSIASWNALD VLTVELYPSD KRTTAFGFLN ALCKLAAVLG ISIFTSFVGI TKAAPILFAS 
    AALALGSSLA LKLPETRGQV LQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.