Details for: SMOC1

Gene ID: 64093

Symbol: SMOC1

Ensembl ID: ENSG00000198732

Description: SPARC related modular calcium binding 1

Associated with

Other Information

Genular Protein ID: 604585913

Symbol: SMOC1_HUMAN

Name: SPARC-related modular calcium-binding protein 1

UniProtKB Accession Codes:

Q9H4F8 A8K1S3 B2R7P5 Q96F78

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CTD 1 ChEBI 9 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 10 Gene3D 3 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 4 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SIGNOR 1 SMART 2 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12130637

Title: Characterization of SMOC-1, a novel modular calcium-binding protein in basement membranes.

PubMed ID: 12130637

DOI: 10.1074/jbc.m203830200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20359165

Title: Secretome analysis of human BMSCs and identification of SMOC1 as an important ECM protein in osteoblast differentiation.

PubMed ID: 20359165

DOI: 10.1021/pr901110q

PubMed ID: 21194678

Title: SMOC1 is essential for ocular and limb development in humans and mice.

PubMed ID: 21194678

DOI: 10.1016/j.ajhg.2010.11.012

PubMed ID: 21194680

Title: Mutations in the SPARC-related modular calcium-binding protein 1 gene, SMOC1, cause waardenburg anophthalmia syndrome.

PubMed ID: 21194680

DOI: 10.1016/j.ajhg.2010.12.002

PubMed ID: 21750680

Title: Loss of the BMP antagonist, SMOC-1, causes Ophthalmo-acromelic (Waardenburg Anophthalmia) syndrome in humans and mice.

PubMed ID: 21750680

DOI: 10.1371/journal.pgen.1002114

PubMed ID: 23646827

Title: Mutations in ALDH1A3 cause Microphthalmia.

PubMed ID: 23646827

DOI: 10.1111/cge.12184

Sequence Information:

  • Length: 434
  • Mass: 48163
  • Checksum: 2CB639212BA42478
  • Sequence:
    • MLPARCARLL TPHLLLVLVQ LSPARGHRTT GPRFLISDRD PQCNLHCSRT QPKPICASDG 
RSYESMCEYQ RAKCRDPTLG VVHRGRCKDA GQSKCRLERA QALEQAKKPQ EAVFVPECGE 
DGSFTQVQCH TYTGYCWCVT PDGKPISGSS VQNKTPVCSG SVTDKPLSQG NSGRKDDGSK 
PTPTMETQPV FDGDEITAPT LWIKHLVIKD SKLNNTNIRN SEKVYSCDQE RQSALEEAQQ 
NPREGIVIPE CAPGGLYKPV QCHQSTGYCW CVLVDTGRPL PGTSTRYVMP SCESDARAKT 
TEADDPFKDR ELPGCPEGKK MEFITSLLDA LTTDMVQAIN SAAPTGGGRF SEPDPSHTLE 
ERVVHWYFSQ LDSNSSNDIN KREMKPFKRY VKKKAKPKKC ARRFTDYCDL NKDKVISLPE 
LKGCLGVSKE GRLV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.