GFRA4 | ENSG00000125861 | NCBI 64096

Details for: GFRA4

Gene ID: 64096

Symbol: GFRA4

Ensembl ID: ENSG00000125861

Description: GDNF family receptor alpha 4

Associated with

Axon guidance
(R-HSA-422475)
Developmental biology
(R-HSA-1266738)
Mapk1/mapk3 signaling
(R-HSA-5684996)
Mapk family signaling cascades
(R-HSA-5683057)
Ncam1 interactions
(R-HSA-419037)
Ncam signaling for neurite out-growth
(R-HSA-375165)
Raf/map kinase cascade
(R-HSA-5673001)
Ret signaling
(R-HSA-8853659)
Signal transduction
(R-HSA-162582)
External side of plasma membrane
(GO:0009897)
Extracellular region
(GO:0005576)
Glial cell-derived neurotrophic factor receptor activity
(GO:0016167)
Glial cell-derived neurotrophic factor receptor signaling pathway
(GO:0035860)
Negative regulation of ossification
(GO:0030279)
Nervous system development
(GO:0007399)
Ossification
(GO:0001503)
Plasma membrane
(GO:0005886)
Receptor complex
(GO:0043235)

Other Information

Proteins

GDNF family receptor alpha-4

Genular Protein ID: 3291417180

Symbol: GFRA4_HUMAN

Name: GDNF family receptor alpha-4

UniProtKB Accession Codes:

Q9GZZ7 Q5JT74 Q9H191 Q9H192

Database IDs:

Citations:

PubMed ID: 11116144

Title: Human glial cell line-derived neurotrophic factor receptor alpha4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cells.

PubMed ID: 11116144

DOI: 10.1074/jbc.m008279200

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 23333276

Title: SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRalpha1 and RET.

PubMed ID: 23333276

DOI: 10.1016/j.celrep.2012.12.011

Sequence Information:

Length: 299
Mass: 31670
Checksum: 8443B8342FF10801
Sequence:

MVRCLGPALL LLLLLGSASS VGGNRCVDAA EACTADARCQ RLRSEYVAQC LGRAAQGGCP 
RARCRRALRR FFARGPPALT HALLFCPCAG PACAERRRQT FVPSCAFSGP GPAPPSCLEP 
LNFCERSRVC RCARAAAGPW RGWGRGLSPA HRPPAAQASP PGLSGLVHPS AQRPRRLPAG 
PGRPLPARLR GPRGVPAGTA VTPNYVDNVS ARVAPWCDCG ASGNRREDCE AFRGLFTRNR 
CLDGAIQAFA SGWPPVLLDQ LNPQGDPEHS LLQVSSTGRA LERRSLLSIL PVLALPALL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.