LIN7B | ENSG00000104863 | NCBI 64130

Details for: LIN7B

Gene ID: 64130

Symbol: LIN7B

Ensembl ID: ENSG00000104863

Description: lin-7 homolog B, crumbs cell polarity complex component

Associated with

Activation of nmda receptors and postsynaptic events
(R-HSA-442755)
Assembly and cell surface presentation of nmda receptors
(R-HSA-9609736)
Dopamine neurotransmitter release cycle
(R-HSA-212676)
Neurexins and neuroligins
(R-HSA-6794361)
Neuronal system
(R-HSA-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-HSA-112314)
Neurotransmitter release cycle
(R-HSA-112310)
Protein-protein interactions at synapses
(R-HSA-6794362)
Rho gtpase effectors
(R-HSA-195258)
Rho gtpases activate rhotekin and rhophilins
(R-HSA-5666185)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Transmission across chemical synapses
(R-HSA-112315)
Basolateral plasma membrane
(GO:0016323)
Bicellular tight junction
(GO:0005923)
Cell-cell junction
(GO:0005911)
Exocytosis
(GO:0006887)
L27 domain binding
(GO:0097016)
Maintenance of epithelial cell apical/basal polarity
(GO:0045199)
Mpp7-dlg1-lin7 complex
(GO:0097025)
Neurotransmitter secretion
(GO:0007269)
Pdz domain binding
(GO:0030165)
Plasma membrane
(GO:0005886)
Postsynaptic density membrane
(GO:0098839)
Presynapse
(GO:0098793)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein kinase binding
(GO:0019901)
Protein localization to basolateral plasma membrane
(GO:1903361)
Protein transport
(GO:0015031)
Synapse
(GO:0045202)

Other Information

Proteins

Protein lin-7 homolog B

Genular Protein ID: 1960394755

Symbol: LIN7B_HUMAN

Name: Protein lin-7 homolog B

UniProtKB Accession Codes:

Q9HAP6

Database IDs:

Citations:

PubMed ID: 11742811

Title: Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex.

PubMed ID: 11742811

DOI: 10.1152/ajpcell.00249.2001

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12967566

Title: Polar expression of ErbB-2/HER2 in epithelia. Bimodal regulation by Lin-7.

PubMed ID: 12967566

DOI: 10.1016/j.devcel.2003.08.001

PubMed ID: 15317815

Title: PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current.

PubMed ID: 15317815

DOI: 10.1074/jbc.m405874200

PubMed ID: 16979770

Title: Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons.

PubMed ID: 16979770

DOI: 10.1016/j.neures.2006.08.003

PubMed ID: 17237226

Title: The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions.

PubMed ID: 17237226

DOI: 10.1074/jbc.m610002200

Sequence Information:

Length: 207
Mass: 22896
Checksum: 63189D82706B9B00
Sequence:

MAALVEPLGL ERDVSRAVEL LERLQRSGEL PPQKLQALQR VLQSRFCSAI REVYEQLYDT 
LDITGSAEIR AHATAKATVA AFTASEGHAH PRVVELPKTD EGLGFNIMGG KEQNSPIYIS 
RVIPGGVADR HGGLKRGDQL LSVNGVSVEG EQHEKAVELL KAAQGSVKLV VRYTPRVLEE 
MEARFEKMRS ARRRQQHQSY SSLESRG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: LIN7B

Associated with

Other Information

Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex. PubMed ID: 11742811

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Polar expression of ErbB-2/HER2 in epithelia. Bimodal regulation by Lin-7. PubMed ID: 12967566

PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current. PubMed ID: 15317815

Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons. PubMed ID: 16979770

The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions. PubMed ID: 17237226