Details for: ABCG4

Gene ID: 64137

Symbol: ABCG4

Ensembl ID: ENSG00000172350

Description: ATP binding cassette subfamily G member 4

Associated with

Other Information

Genular Protein ID: 571918727

Symbol: ABCG4_HUMAN

Name: ATP-binding cassette sub-family G member 4

UniProtKB Accession Codes:

Q9H172 A8K1B5 Q8WWH0 Q8WWH1 Q8WWH2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 13 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 3 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 5 Rhea 4 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 11606068

Title: The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages.

PubMed ID: 11606068

DOI: 10.1006/bbrc.2001.5756

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11856881

Title: Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4.

PubMed ID: 11856881

DOI: 10.1159/000048816

PubMed ID: 12183068

Title: ABCG4: a novel human white family ABC-transporter expressed in the brain and eye.

PubMed ID: 12183068

DOI: 10.1016/s0167-4889(02)00269-0

PubMed ID: 15240127

Title: Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization.

PubMed ID: 15240127

DOI: 10.1016/j.bbrc.2004.06.037

PubMed ID: 27228027

Title: Functional Cooperativity between ABCG4 and ABCG1 Isoforms.

PubMed ID: 27228027

DOI: 10.1371/journal.pone.0156516

PubMed ID: 33141061

Title: Regulation of ABCG4 transporter expression by sterols and LXR ligands.

PubMed ID: 33141061

DOI: 10.1016/j.bbagen.2020.129769

Sequence Information:

  • Length: 646
  • Mass: 71896
  • Checksum: 9CCEC6E150772611
  • Sequence:
    • MAEKALEAVG CGLGPGAVAM AVTLEDGAEP PVLTTHLKKV ENHITEAQRF SHLPKRSAVD 
IEFVELSYSV REGPCWRKRG YKTLLKCLSG KFCRRELIGI MGPSGAGKST FMNILAGYRE 
SGMKGQILVN GRPRELRTFR KMSCYIMQDD MLLPHLTVLE AMMVSANLKL SEKQEVKKEL 
VTEILTALGL MSCSHTRTAL LSGGQRKRLA IALELVNNPP VMFFDEPTSG LDSASCFQVV 
SLMKSLAQGG RTIICTIHQP SAKLFEMFDK LYILSQGQCI FKGVVTNLIP YLKGLGLHCP 
TYHNPADFII EVASGEYGDL NPMLFRAVQN GLCAMAEKKS SPEKNEVPAP CPPCPPEVDP 
IESHTFATST LTQFCILFKR TFLSILRDTV LTHLRFMSHV VIGVLIGLLY LHIGDDASKV 
FNNTGCLFFS MLFLMFAALM PTVLTFPLEM AVFMREHLNY WYSLKAYYLA KTMADVPFQV 
VCPVVYCSIV YWMTGQPAET SRFLLFSALA TATALVAQSL GLLIGAASNS LQVATFVGPV 
TAIPVLLFSG FFVSFKTIPT YLQWSSYLSY VRYGFEGVIL TIYGMERGDL TCLEERCPFR 
EPQSILRALD VEDAKLYMDF LVLGIFFLAL RLLAYLVLRY RVKSER

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.